Novel angiotensin II AT(1) receptor antagonist irbesartan prevents thromboxane A(2)-induced vasoconstriction in canine coronary arteries and human platelet aggregation.
Li P, Fukuhara M, Diz DI, Ferrario CM, Brosnihan KB. Novel angiotensin II AT(1) receptor antagonist irbesartan prevents thromboxane A(2)-induced vasoconstriction in canine coronary arteries and human platelet aggregation. J Pharmacol Exp Ther. 2000 Jan; 292(1):238-46.
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15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
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Animals
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Autoradiography
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Biphenyl Compounds
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Coronary Vessels
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Dogs
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Dose-Response Relationship, Drug
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Drug Interactions
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Humans
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Isometric Contraction
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Male
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Muscle Contraction
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Muscle, Smooth, Vascular
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Platelet Aggregation
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Receptor, Angiotensin, Type 1
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Receptor, Angiotensin, Type 2
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Receptors, Prostaglandin
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Receptors, Thromboxane A2, Prostaglandin H2
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Tetrazoles
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Thromboxane A2
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Time Factors
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Vasoconstrictor Agents