The implications of BRCA loss of heterozygosity (LOH) and deficient mismatch repair gene (dMMR) expression in the breast cancer of a patient with both inherited breast and ovarian cancer syndrome (BRCA2) and Lynch syndrome (MLH1).

Sorscher S, Ansley K, Delaney SD, Ramkissoon S. The implications of BRCA loss of heterozygosity (LOH) and deficient mismatch repair gene (dMMR) expression in the breast cancer of a patient with both inherited breast and ovarian cancer syndrome (BRCA2) and Lynch syndrome (MLH1). Breast Cancer Res Treat. 2020 Apr; 180(2):511-514.

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subject areas

BRCA2 Protein
Breast Neoplasms
Colorectal Neoplasms, Hereditary Nonpolyposis
Female
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Immunotherapy
Loss of Heterozygosity
Middle Aged
Ovarian Neoplasms
Prognosis

authors with profiles

Katherine C. Ansley MD