A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).

Descriptor ID	D016222
MeSH Number(s)	D12.644.276.624.120 D12.776.467.624.120 D23.529.624.120
Concept/Terms	Fibroblast Growth Factor 2 Fibroblast Growth Factor 2 Cartilage-Derived Growth Factor Cartilage Derived Growth Factor Class II Heparin-Binding Growth Factor FGF-2 FGF 2 Prostatropin Fibroblast Growth Factor, Basic Fibroblast Growth Factor-2 HBGF-2 Heparin-Binding Growth Factor Class II Prostate Epithelial Cell Growth Factor Basic Fibroblast Growth Factor FGF2

Below are MeSH descriptors whose meaning is more general than "Fibroblast Growth Factor 2".

Below are MeSH descriptors whose meaning is related to "Fibroblast Growth Factor 2".

Below are MeSH descriptors whose meaning is more specific than "Fibroblast Growth Factor 2".