An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)

Descriptor ID	D004402
MeSH Number(s)	C10.114.750.137.250 C10.177.575.300 C10.314.750.600.250 C10.500.310.309 C10.574.500.496.250 C10.668.829.800.625.200 C10.668.829.800.750.450.250 C16.131.666.310.309 C16.320.400.415.309 C20.111.258.750.600.250
Concept/Terms	Dysautonomia, Familial Dysautonomia, Familial Familial Dysautonomia Hereditary Sensory Neuropathy Type 3 Hereditary Sensory Neuropathy, Dominant, Type 3 Hereditary Sensory Neuropathy, Dominant, Type III Hereditary Sensory Neuropathy, Type 3, Dominant Hereditary-Sensory and Autonomic Neuropathy Type III Hereditary Sensory and Autonomic Neuropathy Type III HSAN (Hereditary Sensory and Autonomic Neuropathy) Type III HSAN 3 HSAN III HSAN Type III Neuropathy, Hereditary and Autonomic, Type III Neuropathy, Hereditary Sensory And Autonomic, Type Iii Riley-Day Syndrome Riley Day Syndrome Type 3 Hereditary Sensory Neuropathy, Dominant Type III Hereditary Sensory Neuropathy, Dominant Dominant Hereditary Sensory Neuropathy, Type III Hereditary Sensory and Autonomic Neuropathy 3

Below are MeSH descriptors whose meaning is more general than "Dysautonomia, Familial".

Below are MeSH descriptors whose meaning is related to "Dysautonomia, Familial".

Below are MeSH descriptors whose meaning is more specific than "Dysautonomia, Familial".