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Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.
Autophagic/lysosomal dysfunction in Alzheimer's disease.
Mammalian Target of Rapamycin at the Crossroad Between Alzheimer's Disease and Diabetes.
Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
Tau protein aggregation is associated with cellular senescence in the brain.
Novel Stem Cell and Mouse Models to Study Frontotemporal Dementia
Alzheimer's Disease Associated Tau Toxicity Induces Cellular Senescence in Brain
Aging-related Alzheimer's disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus).
Phase II Clinical Trial to Evaluate the Safety and Feasibility of Senolytic Therapy in Alzheimer’s Disease
Evaluating microtubule binding as a potential imaging biomarker for Alzheimer's disease
Alzheimer’s disease-associated tau toxicity induces cellular senescence in the brain.
Biological aging processes underlying cognitive decline and neurodegenerative disease.
Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer's disease: review, recommendation, implementation and application.
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial.
A geroscience motivated approach to treat Alzheimer's disease: Senolytics move to clinical trials.
Can oral health and oral-derived biospecimens predict progression of dementia?