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One or more keywords matched the following properties of Lockhart, Samuel
keywords Aging
overview Samuel N. Lockhart, Ph.D., is a neuroscientist who has spent his research career disentangling normal brain aging from preclinical disease. He earned his Ph.D. in Neuroscience from UC Davis with Dr. Charles DeCarli, investigating the impacts of age and cerebrovascular disease on brain function and cognition, and completed a postdoctoral fellowship with Dr. William Jagust at UC Berkeley, examining how tau and amyloid accumulation affect brain structure and cognitive trajectories. He is an author of publications that have appeared in Neuron, NeuroImage, Neurology, Journal of Neuroscience, Brain, Stroke, Journal of Nuclear Medicine, and JAMA Neurology, among others. At Wake Forest, Dr. Lockhart is an Assistant Professor of Internal Medicine and Gerontology and Geriatric Medicine. He plans to build a research program in multimodal neuroimaging and cognitive analyses of aging and diseases of aging, with a focus on interactions between metabolic dysfunction and vascular and degenerative pathology.
One or more keywords matched the following items that are connected to Lockhart, Samuel
Item TypeName
Concept National Institute on Aging (U.S.)
Academic Article Tau and ß-Amyloid Are Associated with Medial Temporal Lobe Structure, Function, and Memory Encoding in Normal Aging.
Academic Article Amyloid and tau PET demonstrate region-specific associations in normal older people.
Academic Article Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging.
Academic Article White matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain.
Academic Article White matter hyperintensities are associated with visual search behavior independent of generalized slowing in aging.
Academic Article Neuroimaging of the aging brain: introduction to the special issue of neuropsychology review.
Academic Article Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease.
Academic Article Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease.
Academic Article The role of diffusion tensor imaging in the study of cognitive aging.
Academic Article PET Imaging of Tau Deposition in the Aging Human Brain.
Academic Article Structural imaging measures of brain aging.
Academic Article Entorhinal Tau Pathology, Episodic Memory Decline, and Neurodegeneration in Aging.
Academic Article Subthreshold Amyloid Predicts Tau Deposition in Aging.
Grant Biomarkers of preclinical Alzheimer disease and cognition
Academic Article The contributions of MRI-based measures of gray matter, white matter hyperintensity, and white matter integrity to late-life cognition.
Academic Article Vascular dysfunction-The disregarded partner of Alzheimer's disease.
Academic Article Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for Alzheimer's disease: a pilot study.
Academic Article Differences in neuroimaging features of early- versus late-onset nonfluent/agrammatic primary progressive aphasia.
Academic Article Early Alzheimer's disease-like reductions in gray matter and cognitive function with aging in nonhuman primates.
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