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Hollis, Thomas

One or more keywords matched the following items that are connected to Hollis, Thomas

Item Type	Name
Academic Article	The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
Academic Article	The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering.
Concept	Structure-Activity Relationship
Academic Article	The TREX1 C-terminal region controls cellular localization through ubiquitination.

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