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Gmeiner, William
One or more keywords matched the following items that are connected to Gmeiner, William
Item TypeName
Academic Article Gemcitabine (2',2'-difluoro-2'-deoxycytidine), an antimetabolite that poisons topoisomerase I.
Academic Article NMR structure of a gemcitabine-substituted model Okazaki fragment.
Academic Article Antimetabolite incorporation into DNA: structural and thermodynamic basis for anticancer activity.
Academic Article Structural basis for topoisomerase I inhibition by nucleoside analogs.
Academic Article Replication-dependent irreversible topoisomerase 1 poisoning is responsible for FdUMP[10] anti-leukemic activity.
Academic Article Solution structures of 5-fluorouracil-substituted RNA duplexes containing G-U wobble base pairs.
Academic Article Cytarabine-induced destabilization of a model Okazaki fragment.
Academic Article Cytarabine-induced destabilization and bending of a model Okazaki fragment.
Academic Article Increased cytotoxicity and decreased in vivo toxicity of FdUMP[10] relative to 5-FU.
Academic Article Positive interaction between 5-FU and FdUMP[10] in the inhibition of human colorectal tumor cell proliferation.
Concept Antimetabolites, Antineoplastic
Academic Article TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.
Academic Article Selective anti-tumor activity of the novel fluoropyrimidine polymer F10 towards G48a orthotopic GBM tumors.
Academic Article Chemistry of Fluorinated Pyrimidines in the Era of Personalized Medicine.
Search Criteria
  • Antimetabolites Antineoplastic