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Severely impaired B lymphocyte proliferation, survival, and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background.
CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms.
The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease: systemic sclerosis as a model system.
Antigens, Differentiation, B-Lymphocyte
Antigens Differentiation B Lymphocyte