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Parks, John

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Item Type	Name
Academic Article	Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I.
Academic Article	HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney.
Academic Article	Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.
Academic Article	Reduction in ABCG1 in Type 2 diabetic mice increases macrophage foam cell formation.
Academic Article	Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels.
Academic Article	Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.
Academic Article	Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons.
Academic Article	Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.
Academic Article	Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism.
Academic Article	Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation.
Academic Article	Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.
Academic Article	Hepatic ABCA1 and VLDL triglyceride production.
Academic Article	ATP-binding cassette transporter AI and its role in HDL formation.
Academic Article	Hepatic ATP-binding cassette transporter A1 is a key molecule in high-density lipoprotein cholesteryl ester metabolism in mice.
Academic Article	Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Academic Article	Minimal lipidation of pre-beta HDL by ABCA1 results in reduced ability to interact with ABCA1.
Academic Article	Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages.
Academic Article	Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.
Academic Article	LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.
Academic Article	Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.
Academic Article	An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2.
Academic Article	Apolipoprotein M expression increases the size of nascent pre beta HDL formed by ATP binding cassette transporter A1.
Academic Article	ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.
Academic Article	ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions.
Academic Article	A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion.
Academic Article	An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.
Academic Article	Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol.
Academic Article	Hepatic ABC transporters and triglyceride metabolism.
Academic Article	Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers.
Academic Article	Myeloid cell-specific ABCA1 deletion protects mice from bacterial infection.
Academic Article	ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development.
Academic Article	Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration.
Concept	ATP-Binding Cassette Transporters
Concept	Adenosine Triphosphate
Academic Article	Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Academic Article	Liver ABCA1 deletion in LDLrKO mice does not impair macrophage reverse cholesterol transport or exacerbate atherogenesis.
Academic Article	Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models.
Academic Article	Lipid absorption defects in intestine-specific microsomal triglyceride transfer protein and ATP-binding cassette transporter A1-deficient mice.
Academic Article	Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice.
Academic Article	Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling.
Academic Article	LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling.
Academic Article	Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice.
Academic Article	MicroRNA-33 Regulates the Innate Immune Response via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains.
Grant	Hepatocyte Abca1, cholesterol trafficking, and lipid mobilization
Grant	Macrophage, ABCA1, Inflammation, and Atherosclerosis
Academic Article	Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis.
Academic Article	Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.
Academic Article	Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.
Academic Article	LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.
Academic Article	Targeted Deletion of Adipocyte Abca1 (ATP-Binding Cassette Transporter A1) Impairs Diet-Induced Obesity.
Academic Article	Targeted Deletion of Hepatocyte Abca1 Increases Plasma HDL (High-Density Lipoprotein) Reverse Cholesterol Transport via the LDL (Low-Density Lipoprotein) Receptor.

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