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Search Results to Mei-Chuan Ko, Ph.D.

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One or more keywords matched the following items that are connected to Ko, Mei-Chuan

Item TypeName
Concept Animals
Concept Behavior, Animal
Concept Disease Models, Animal
Academic Article Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112.
Academic Article Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/µ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain.
Academic Article Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice.
Academic Article The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys.
Academic Article Cocaine esterase: interactions with cocaine and immune responses in mice.
Academic Article Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.
Academic Article The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats.
Academic Article The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination.
Academic Article Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys.
Academic Article Effects of atypical kappa-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates.
Academic Article Roles of µ-opioid receptors and nociceptin/orphanin FQ peptide receptors in buprenorphine-induced physiological responses in primates.
Academic Article Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.
Academic Article Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys.
Academic Article Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats.
Academic Article The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability.
Academic Article Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine.
Academic Article Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase.
Academic Article Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats.
Academic Article Central kappa-opioid receptor-mediated antidepressant-like effects of nor-Binaltorphimine: behavioral and BDNF mRNA expression studies.
Academic Article Effects of butorphanol on morphine-induced itch and analgesia in primates.
Academic Article Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
Academic Article Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats.
Academic Article Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys.
Academic Article The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies.
Academic Article Most efficient cocaine hydrolase designed by virtual screening of transition states.
Academic Article Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity.
Academic Article Effects of cocaine esterase following its repeated administration with cocaine in mice.
Academic Article PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity.
Academic Article Pharmacokinetic evidence for the long-lasting effect of nor-binaltorphimine, a potent kappa opioid receptor antagonist, in mice.
Academic Article Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain.
Academic Article [Dmt1]N/OFQ(1-13)-NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist.
Academic Article Seizure activity involved in the up-regulation of BDNF mRNA expression by activation of central mu opioid receptors.
Academic Article Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies.
Academic Article Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects.
Academic Article Differential in vivo potencies of naltrexone and 6beta-naltrexol in the monkey.
Academic Article Antinociceptive, hypothermic, hypotensive, and reinforcing effects of a novel neurotensin receptor agonist, NT69L, in rhesus monkeys.
Academic Article Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.
Academic Article The role of central mu opioid receptors in opioid-induced itch in primates.
Academic Article Characterization of scratching responses in rats following centrally administered morphine or bombesin.
Academic Article Ultra-long antagonism of kappa opioid agonist-induced diuresis by intracisternal nor-binaltorphimine in monkeys.
Academic Article Effect of opioid receptor antagonists on hypothalamic-pituitary-adrenal activity in rhesus monkeys.
Academic Article Studies of micro-, kappa-, and delta-opioid receptor density and G protein activation in the cortex and thalamus of monkeys.
Academic Article Activation of kappa-opioid receptors inhibits pruritus evoked by subcutaneous or intrathecal administration of morphine in monkeys.
Academic Article Relative reinforcing effects of three opioids with different durations of action.
Academic Article Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors.
Academic Article Gangrenous Clostridium perfringens infection and subsequent wound management in a rhesus macaque (Macaca mulatta).
Academic Article Comparison of the opioid receptor antagonist properties of naltrexone and 6 beta-naltrexol in morphine-naïve and morphine-dependent mice.
Academic Article Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists.
Academic Article Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats.
Academic Article Neuraxial opioid-induced itch and its pharmacological antagonism.
Academic Article Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates.
Academic Article TC-2559, an a4ß2 nicotinic acetylcholine receptor agonist, suppresses the expression of CCL3 and IL-1ß through STAT3 inhibition in cultured murine macrophages.
Academic Article Central N/OFQ-NOP Receptor System in Pain Modulation.
Academic Article Spinal Functions of B-Type Natriuretic Peptide, Gastrin-Releasing Peptide, and Their Cognate Receptors for Regulating Itch in Mice.
Academic Article Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys.
Academic Article Supraspinal actions of nociceptin/orphanin FQ, morphine and substance P in regulating pain and itch in non-human primates.
Academic Article GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys.
Academic Article Local inhibitory effects of dynorphin A-(1-17) on capsaicin-induced thermal allodynia in rhesus monkeys.
Academic Article Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine in rhesus monkeys.
Academic Article An experimental itch model in monkeys: characterization of intrathecal morphine-induced scratching and antinociception.
Academic Article Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats.
Academic Article Activation of peripheral kappa opioid receptors inhibits capsaicin-induced thermal nociception in rhesus monkeys.
Academic Article Local administration of delta9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: a peripheral cannabinoid action.
Academic Article Intracisternal nor-binaltorphimine distinguishes central and peripheral kappa-opioid antinociception in rhesus monkeys.
Academic Article The effects of the phyllolitorin analogue [desTrp(3), Leu(8)]phyllolitorin on scratching induced by bombesin and related peptides in rats.
Academic Article Differentiation of kappa opioid agonist-induced antinociception by naltrexone apparent pA2 analysis in rhesus monkeys.
Academic Article kappa-Opioid receptor binding populations in rhesus monkey brain: relationship to an assay of thermal antinociception.
Academic Article The role of peripheral mu opioid receptors in the modulation of capsaicin-induced thermal nociception in rhesus monkeys.
Academic Article Chronic effects of haloperidol and SCH23390 on operant and licking behaviors in the rat.
Academic Article A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates.
Academic Article Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys.
Academic Article Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13).
Academic Article Differential mRNA expression of neuroinflammatory modulators in the spinal cord and thalamus of type 2 diabetic monkeys.
Academic Article A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates.
Academic Article Effects of NOP-Related Ligands in Nonhuman Primates.
Academic Article Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons.
Academic Article BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates.
Academic Article Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys.
Academic Article Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch.
Academic Article GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn.
Academic Article Antinociceptive, reinforcing, and pruritic effects of the G-protein signalling-biased mu opioid receptor agonist PZM21 in non-human primates.
Academic Article STING controls nociception via type I interferon signalling in sensory neurons.

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