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One or more keywords matched the following items that are connected to Orr, Miranda
Item TypeName
Concept Aging
Academic Article Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.
Academic Article Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.
Academic Article Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice.
Academic Article Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.
Academic Article Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.
Academic Article Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
Academic Article Tau protein aggregation is associated with cellular senescence in the brain.
Grant Alzheimer's Disease Associated Tau Toxicity Induces Cellular Senescence in Brain
Grant High Resolution Profiling of Senescent Neurons and Their Microenvironments in Postmortem Human Brain Tissue Spanning Eight Decades of Life
Academic Article Aging-related Alzheimer's disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus).
Grant Development of an Innovative Vervet (Chlorocebus aethiops sabaeus) Model of Early Alzheimer's-like Neuropathology and Symptomatology
Grant Investigating the Role of Tau Protein in Neuronal Senescence Induction and Maintenance
Grant Cell Senescence and Death in Neurodegenerative Diseases
Grant Alzheimer’s disease-associated tau toxicity induces cellular senescence in the brain.
Academic Article Biological aging processes underlying cognitive decline and neurodegenerative disease.
Academic Article Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.
Academic Article Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial.
Academic Article The landscape of human tissue and cell type specific expression and co-regulation of senescence genes.
Academic Article A geroscience motivated approach to treat Alzheimer's disease: Senolytics move to clinical trials.
Academic Article The Cellular Senescence Stress Response in Post-Mitotic Brain Cells: Cell Survival at the Expense of Tissue Degeneration.
Academic Article Evidence of the Cellular Senescence Stress Response in Mitotically Active Brain Cells-Implications for Cancer and Neurodegeneration.
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  • Aging