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Orr, Miranda

One or more keywords matched the following items that are connected to Orr, Miranda

Item Type	Name
Concept	Aging
Academic Article	Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.
Academic Article	Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.
Academic Article	Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice.
Academic Article	Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.
Academic Article	Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.
Academic Article	Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
Academic Article	Tau protein aggregation is associated with cellular senescence in the brain.
Grant	Alzheimer's Disease Associated Tau Toxicity Induces Cellular Senescence in Brain
Grant	High Resolution Profiling of Senescent Neurons and Their Microenvironments in Postmortem Human Brain Tissue Spanning Eight Decades of Life
Academic Article	Aging-related Alzheimer's disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus).
Grant	Development of an Innovative Vervet (Chlorocebus aethiops sabaeus) Model of Early Alzheimer's-like Neuropathology and Symptomatology
Grant	Investigating the Role of Tau Protein in Neuronal Senescence Induction and Maintenance
Grant	Cell Senescence and Death in Neurodegenerative Diseases
Grant	Alzheimer’s disease-associated tau toxicity induces cellular senescence in the brain.
Academic Article	Biological aging processes underlying cognitive decline and neurodegenerative disease.
Academic Article	Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.
Academic Article	Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial.
Academic Article	The landscape of human tissue and cell type specific expression and co-regulation of senescence genes.
Academic Article	A geroscience motivated approach to treat Alzheimer's disease: Senolytics move to clinical trials.
Academic Article	The Cellular Senescence Stress Response in Post-Mitotic Brain Cells: Cell Survival at the Expense of Tissue Degeneration.
Academic Article	Evidence of the Cellular Senescence Stress Response in Mitotically Active Brain Cells-Implications for Cancer and Neurodegeneration.

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Aging