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Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats.
Receptors, Dopamine D2
Dopamine Uptake Inhibitors
Dopamine Plasma Membrane Transport Proteins
Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration.
Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood.
Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala.
Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum.
Optogenetically-induced tonic dopamine release from VTA-nucleus accumbens projections inhibits reward consummatory behaviors.
Translational Studies on Early-life Stress and Vulnerability to Alcohol Addiction
Exploring the consequences of social defeat stress and intermittent ethanol drinking on dopamine dynamics in the rat nucleus accumbens.
Chronic Social Isolation Stress during Peri-Adolescence Alters Presynaptic Dopamine Terminal Dynamics via Augmentation in Accumbal Dopamine Availability.
Opposite Consequences of Tonic and Phasic Increases in Accumbal Dopamine on Alcohol-Seeking Behavior.