D004250Chemicals & DrugsD08.811.399.403.741340.998928DNA Topoisomerases, Type IIFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonEmergency MedicinePathologyWake Forest School of MedicineDanielleRayDanielle S. Ray MD36.08959100000000-80.26859900000000186Ray, DanielleClinical AffiliateAlexeiMikhailovAlexei V. Mikhailov MD, PhD36.08915800000000-80.266862000000002208Mikhailov, AlexeiAssistant ProfessorCaio MaxRocha LimaCaio Max S. Rocha Lima MD, MS2211Rocha Lima, Caio MaxProfessor15821136Downey N, Hines JC, Sinha KM, Ray DSEukaryotic cellDowney N, Hines JC, Sinha KM, Ray DS. Mitochondrial DNA ligases of Trypanosoma brucei. Eukaryot Cell. 2005 Apr; 4(4):765-74.Eukaryot Cell2005-04-01T00:00:002005Mitochondrial DNA ligases of Trypanosoma brucei.15611649Mikhailov A, Shinohara M, Rieder CLCell cycle (Georgetown, Tex.)Mikhailov A, Shinohara M, Rieder CL. The p38-mediated stress-activated checkpoint. A rapid response system for delaying progression through antephase and entry into mitosis. . 2005 Jan; 4(1):57-62.2005-01-11T00:00:002005The p38-mediated stress-activated checkpoint. A rapid response system for delaying progression through antephase and entry into mitosis.16928835Simon GR, Lush RM, Gump J, Tetteh L, Williams C, Cantor A, Antonia S, Garrett C, Rocha-Lima C, Fishman M, Sullivan DM, Munster PNMolecular cancer therapeuticsSimon GR, Lush RM, Gump J, Tetteh L, Williams C, Cantor A, Antonia S, Garrett C, Rocha-Lima C, Fishman M, Sullivan DM, Munster PN. Sequential oral 9-nitrocamptothecin and etoposide: a pharmacodynamic- and pharmacokinetic-based phase I trial. . 2006 Aug; 5(8):2130-7.2006-08-01T00:00:002006Sequential oral 9-nitrocamptothecin and etoposide: a pharmacodynamic- and pharmacokinetic-based phase I trial.20Professor24Assistant Professor24040417Dillon LW, Pierce LC, Lehman CE, Nikiforov YE, Wang YHPloS oneDillon LW, Pierce LC, Lehman CE, Nikiforov YE, Wang YH. DNA topoisomerases participate in fragility of the oncogene RET. PLoS One. 2013; 8(9):e75741.PLoS One2013-09-11T00:00:002013DNA topoisomerases participate in fragility of the oncogene RET.Internal Medicine, Hematology & Oncologytrue1Clinical AffiliateClinical Affiliatetrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professor20601956Haffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, Isaacs WB, Bova GS, Liu W, Xu J, Meeker AK, Netto G, De Marzo AM, Nelson WG, Yegnasubramanian SNature geneticsHaffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, Isaacs WB, Bova GS, Liu W, Xu J, Meeker AK, Netto G, De Marzo AM, Nelson WG, Yegnasubramanian S. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat Genet. 2010 Aug; 42(8):668-75.Nat Genet2010-07-04T00:00:002010Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements.0.1297750.01845913research area of0.4840810.06252376subject area for