D034741Chemicals & DrugsD13.150.650.700D13.444.735.150.700D13.444.735.790.537611020.950994RNA, Small InterferingFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonHerbertBonkovskyHerbert L. Bonkovsky MD36.09032400000000-80.266491000000001707Bonkovsky, HerbertProfessorBiochemistryWake Forest School of MedicineWesleyHsuWesley Hsu MD, FAACS36.08959100000000-80.268599000000001154Hsu, WesleyAssociate ProfessorAnthonyAtalaAnthony Atala MD36.08943500000000-80.268632000000003Atala, AnthonyProfessor20ProfessorMichaelShapiroMichael D. Shapiro DO2451Shapiro, MichaelProfessor31782112German CA, Shapiro MDBioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapyGerman CA, Shapiro MD. Small Interfering RNA Therapeutic Inclisiran: A New Approach to Targeting PCSK9. BioDrugs. 2020 Feb; 34(1):1-9.BioDrugs2020-02-01T00:00:002020Small Interfering RNA Therapeutic Inclisiran: A New Approach to Targeting PCSK9.Internal Medicine, Cardiovascular MedicineInternal Medicine, GastroenterologyNeurological SurgeryUrology29130960Han YN, Li Y, Xia SQ, Zhang YY, Zheng JH, Li WCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyHan YN, Li Y, Xia SQ, Zhang YY, Zheng JH, Li W. PIWI Proteins and PIWI-Interacting RNA: Emerging Roles in Cancer. Cell Physiol Biochem. 2017; 44(1):1-20.Cell Physiol Biochem2017-11-03T00:00:002017PIWI Proteins and PIWI-Interacting RNA: Emerging Roles in Cancer.http://www.wfirm.orgWFIRM30702345Coblentz PD, Ahn B, Hayward LF, Yoo JK, Christou DD, Ferreira LFAmerican journal of physiology. Lung cellular and molecular physiologyCoblentz PD, Ahn B, Hayward LF, Yoo JK, Christou DD, Ferreira LF. Small-hairpin RNA and pharmacological targeting of neutral sphingomyelinase prevent diaphragm weakness in rats with heart failure and reduced ejection fraction. Am J Physiol Lung Cell Mol Physiol. 2019 04 01; 316(4):L679-L690.Am J Physiol Lung Cell Mol Physiol2019-01-31T00:00:002019Small-hairpin RNA and pharmacological targeting of neutral sphingomyelinase prevent diaphragm weakness in rats with heart failure and reduced ejection fraction.KeithGagnonKeith T. Gagnon3847Gagnon, KeithAssociate Professor32282904Habibian M, Harikrishna S, Fakhoury J, Barton M, Ageely EA, Cencic R, Fakih HH, Katolik A, Takahashi M, Rossi J, Pelletier J, Gagnon KT, Pradeepkumar PI, Damha MJNucleic acids researchHabibian M, Harikrishna S, Fakhoury J, Barton M, Ageely EA, Cencic R, Fakih HH, Katolik A, Takahashi M, Rossi J, Pelletier J, Gagnon KT, Pradeepkumar PI, Damha MJ. Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference. Nucleic Acids Res. 2020 May 21; 48(9):4643-4657.Nucleic Acids Res2020-05-21T00:00:002020Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference.30907681Gagnon KT, Corey DRNucleic acid therapeuticsGagnon KT, Corey DR. Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs. Nucleic Acid Ther. 2019 Jun; 29(3):116-122.Nucleic Acid Ther2019-03-23T00:00:002019Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs.true1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessor1.874220.017882961research area of0.7697440.0616401141subject area for