D012264Chemicals & DrugsD08.811.682.810660.995256Ribonucleotide Reductasesprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson25402485Cook GJ, Caudell DL, Elford HL, Pardee TSPloS oneCook GJ, Caudell DL, Elford HL, Pardee TS. The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML. PLoS One. 2014; 9(11):e112619.PLoS One2014-11-17T00:00:002014The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML.AnesthesiologyWake Forest School of MedicineTimothyPardeeTimothy S. Pardee MD, PhD36.08959100000000-80.268599000000001000Pardee, TimothyAssistant ProfessorBarbaraYozaBarbara K. Yoza PhD36.08959100000000-80.26859900000000113Yoza, BarbaraProfessorCharlesMcCallCharles E. McCall MD36.09032400000000-80.26649100000000144McCall, CharlesProfessorGregoryKuceraGregory L. Kucera PhD36.08919100000000-80.26677800000000312Kucera, GregoryProfessorOsvaldoDelbonoOsvaldo Delbono MD, PhD36.08977400000000-80.26684000000000730Delbono, OsvaldoProfessor25909427Smith LM, Wells JD, Vachharajani VT, Yoza BK, McCall CE, Hoth JJThe journal of trauma and acute care surgerySmith LM, Wells JD, Vachharajani VT, Yoza BK, McCall CE, Hoth JJ. SIRT1 mediates a primed response to immune challenge after traumatic lung injury. J Trauma Acute Care Surg. 2015 May; 78(5):1034-8.J Trauma Acute Care Surg2015-05-01T00:00:002015SIRT1 mediates a primed response to immune challenge after traumatic lung injury.29596868Nunez Lopez YO, Messi ML, Pratley RE, Zhang T, Delbono OExperimental gerontologyNunez Lopez YO, Messi ML, Pratley RE, Zhang T, Delbono O. Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. Exp Gerontol. 2018 07 15; 108:35-40.Exp Gerontol2018-03-27T00:00:002018Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.23249808Mannava S, Moparthy KC, Wheeler LJ, Leonova KI, Wawrzyniak JA, Bianchi-Smiraglia A, Berman AE, Flanagan S, Shewach DS, Zeitouni NC, Gudkov AV, Mathews CK, Nikiforov MAAgingMannava S, Moparthy KC, Wheeler LJ, Leonova KI, Wawrzyniak JA, Bianchi-Smiraglia A, Berman AE, Flanagan S, Shewach DS, Zeitouni NC, Gudkov AV, Mathews CK, Nikiforov MA. Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion. Aging (Albany NY). 2012 Dec; 4(12):917-22.Aging (Albany NY)2012-12-01T00:00:002012Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion.23245831Mannava S, Moparthy KC, Wheeler LJ, Natarajan V, Zucker SN, Fink EE, Im M, Flanagan S, Burhans WC, Zeitouni NC, Shewach DS, Mathews CK, Nikiforov MAThe American journal of pathologyMannava S, Moparthy KC, Wheeler LJ, Natarajan V, Zucker SN, Fink EE, Im M, Flanagan S, Burhans WC, Zeitouni NC, Shewach DS, Mathews CK, Nikiforov MA. Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence. Am J Pathol. 2013 Jan; 182(1):142-51.Am J Pathol2012-12-12T00:00:002012Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence.Family & Community MedicineInternal Medicine, Molecular MedicineOrthopedic Surgery true1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor0.6599350.03268416research area of0.663080.06050446subject area for