D051176Chemicals & DrugsD12.776.091.249D12.776.220.145.500D12.776.930.13022370.965874beta CateninFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonKounosukeWatabeKounosuke Watabe PhD36.09032400000000-80.266491000000001727Watabe, KounosukeProfessorBiochemistryCancer BiologyPathologyWake Forest School of MedicineAnthonyAtalaAnthony Atala MD36.08943500000000-80.268632000000003Atala, AnthonyProfessor29795437Kim G, Kurnit KC, Djordjevic B, Singh C, Munsell MF, Wang WL, Lazar AJ, Zhang W, Broaddus RModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncKim G, Kurnit KC, Djordjevic B, Singh C, Munsell MF, Wang WL, Lazar AJ, Zhang W, Broaddus R. Nuclear ß-catenin localization and mutation of the CTNNB1 gene: a context-dependent association. Mod Pathol. 2018 10; 31(10):1553-1559.Mod Pathol2018-05-24T00:00:002018Nuclear ß-catenin localization and mutation of the CTNNB1 gene: a context-dependent association.20ProfessorUrologyhttp://www.wfirm.orgWFIRMPeterClarkPeter E. Clark MD3196Clark, PeterClinical Professor28701516Nlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LSJournal of the American Society of Nephrology : JASNNlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LS. Blocking TGF-ß and ß-Catenin Epithelial Crosstalk Exacerbates CKD. J Am Soc Nephrol. 2017 Dec; 28(12):3490-3503.J Am Soc Nephrol2017-07-12T00:00:002017Blocking TGF-ß and ß-Catenin Epithelial Crosstalk Exacerbates CKD.28695795Polosukhina D, Love HD, Moses HL, Lee E, Zent R, Clark PEOncology researchPolosukhina D, Love HD, Moses HL, Lee E, Zent R, Clark PE. Pharmacologic Inhibition of ß-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor. Oncol Res. 2017 Nov 02; 25(9):1653-1664.Oncol Res2017-07-10T00:00:002017Pharmacologic Inhibition of ß-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor.HaodongXuHaodong Xu MD, PhD3737Xu, HaodongProfessorYusukeTakahashiYusuke Takahashi PhD3842Takahashi, YusukeAssociate Professor31419437Zhao L, Sun L, Lu Y, Li F, Xu HJournal of molecular and cellular cardiologyZhao L, Sun L, Lu Y, Li F, Xu H. A small-molecule LF3 abrogates ß-catenin/TCF4-mediated suppression of NaV1.5 expression in HL-1 cardiomyocytes. J Mol Cell Cardiol. 2019 Oct; 135:90-96.J Mol Cell Cardiol2019-08-13T00:00:002019A small-molecule LF3 abrogates ß-catenin/TCF4-mediated suppression of NaV1.5 expression in HL-1 cardiomyocytes.31125668Huo R, Hu C, Zhao L, Sun L, Wang N, Lu Y, Ye B, Deb A, Li F, Xu HHeart rhythmHuo R, Hu C, Zhao L, Sun L, Wang N, Lu Y, Ye B, Deb A, Li F, Xu H. Enhancement of ß-catenin/T-cell factor 4 signaling causes susceptibility to cardiac arrhythmia by suppressing NaV1.5 expression in mice. Heart Rhythm. 2019 Nov; 16(11):1720-1728.Heart Rhythm2019-05-22T00:00:002019Enhancement of ß-catenin/T-cell factor 4 signaling causes susceptibility to cardiac arrhythmia by suppressing NaV1.5 expression in mice.true1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Clinical ProfessorClinical Professortrue1ProfessorProfessor2.238510.013370822research area of0.7296330.046028142subject area for