LeahSolberg WoodsLeah C. Solberg Woods PhD1967Solberg Woods, LeahCatherineProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD051381Living Beings21214250.753638RatsD002874Procedures402130.930667Chromosome MappingD055106Procedures536150.804794Genome-Wide Association StudyD050154Physiology582080.873525AdiposityBiochemistryWake Forest School of MedicineSuzanneCraftSuzanne Craft PhD36.08884000000000-80.270162000000001320Craft, SuzanneProfessorCarlLangefeldCarl D. Langefeld PhD36.09550200000000-80.24393700000000149Langefeld, CarlProfessorCarolShivelyCarol A. Shively PhD36.08943500000000-80.26863200000000173Shively, CarolProfessorDonaldBowdenDonald W. Bowden PhD36.09040200000000-80.26700599999999192Bowden, DonaldProfessorJohnParksJohn S. Parks PhD36.08943500000000-80.26863200000000464Parks, JohnProfessorLynneWagenknechtLynne E. Wagenknecht DrPH36.09562300000000-80.27569400000000595Wagenknecht, LynneProfessorNicholetteAllredNicholette D. Allred PhD36.09040200000000-80.26700599999999706Allred, NicholetteProfessorBarryFreedmanBarry I. Freedman MD36.08959100000000-80.2685990000000078Freedman, BarryProfessorThomasRegisterThomas C. Register PhD36.08943500000000-80.26863200000000803Register, ThomasProfessorDonaldMcclainDonald A. Mcclain MD, PhD36.08977400000000-80.266840000000001732Mcclain, DonaldProfessor1.902380.0200108123research areas0.1671920.04343965coauthor of80.48336.4832748similar to1124selected publicationsAuthorship 501481Authorship 502381Authorship 502637Authorship 503166Authorship 503541Authorship 5071320Authorship 507305Authorship 509986Authorship 511471Authorship 511691Authorship 51209218518967Nosek K, Dennis K, Andrus BM, Ahmadiyeh N, Baum AE, Solberg Woods LC, Redei EEBehavioral and brain functions : BBFNosek K, Dennis K, Andrus BM, Ahmadiyeh N, Baum AE, Solberg Woods LC, Redei EE. Context and strain-dependent behavioral response to stress. Behav Brain Funct. 2008 Jun 02; 4:23.Behav Brain Funct2008-06-02T00:00:002008Context and strain-dependent behavioral response to stress.24326347Solberg Woods LCPhysiological genomicsSolberg Woods LC. QTL mapping in outbred populations: successes and challenges. Physiol Genomics. 2014 Feb 01; 46(3):81-90.Physiol Genomics2013-12-10T00:00:002013QTL mapping in outbred populations: successes and challenges.19697080Solberg Woods LC, Ahmadiyeh N, Baum A, Shimomura K, Li Q, Steiner DF, Turek FW, Takahashi JS, Churchill GA, Redei EEMammalian genome : official journal of the International Mammalian Genome SocietySolberg Woods LC, Ahmadiyeh N, Baum A, Shimomura K, Li Q, Steiner DF, Turek FW, Takahashi JS, Churchill GA, Redei EE. Identification of genetic loci involved in diabetes using a rat model of depression. Mamm Genome. 2009 Aug; 20(8):486-97.Mamm Genome2009-08-22T00:00:002009Identification of genetic loci involved in diabetes using a rat model of depression.19584172Nobrega MA, Solberg Woods LC, Fleming S, Jacob HJPhysiological genomicsNobrega MA, Solberg Woods LC, Fleming S, Jacob HJ. Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat. Physiol Genomics. 2009 Sep 09; 39(1):38-46.Physiol Genomics2009-07-07T00:00:002009Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat.20219828Solberg Woods LC, Stelloh C, Regner KR, Schwabe T, Eisenhauer J, Garrett MRAmerican journal of physiology. Renal physiologySolberg Woods LC, Stelloh C, Regner KR, Schwabe T, Eisenhauer J, Garrett MR. Heterogeneous stock rats: a new model to study the genetics of renal phenotypes. Am J Physiol Renal Physiol. 2010 Jun; 298(6):F1484-91.Am J Physiol Renal Physiol2010-03-10T00:00:002010Heterogeneous stock rats: a new model to study the genetics of renal phenotypes.20068026Solberg Woods LC, Holl K, Tschannen M, Valdar WPhysiological genomicsSolberg Woods LC, Holl K, Tschannen M, Valdar W. Fine-mapping a locus for glucose tolerance using heterogeneous stock rats. Physiol Genomics. 2010 Mar 03; 41(1):102-8.Physiol Genomics2010-01-12T00:00:002010Fine-mapping a locus for glucose tolerance using heterogeneous stock rats.23791960Parker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AANeuropharmacologyParker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AA. Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics. Neuropharmacology. 2014 Jan; 76 Pt B:250-8.Neuropharmacology2013-06-18T00:00:002013Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics.23710681Richards JB, Lloyd DR, Kuehlewind B, Militello L, Paredez M, Solberg Woods L, Palmer AAGenes, brain, and behaviorRichards JB, Lloyd DR, Kuehlewind B, Militello L, Paredez M, Solberg Woods L, Palmer AA. Strong genetic influences on measures of behavioral-regulation among inbred rat strains. Genes Brain Behav. 2013 Jul; 12(5):490-502.Genes Brain Behav2013-06-19T00:00:002013Strong genetic influences on measures of behavioral-regulation among inbred rat strains.22947656Solberg Woods LC, Holl KL, Oreper D, Xie Y, Tsaih SW, Valdar WPhysiological genomicsSolberg Woods LC, Holl KL, Oreper D, Xie Y, Tsaih SW, Valdar W. Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats. Physiol Genomics. 2012 Nov 01; 44(21):1013-26.Physiol Genomics2012-09-04T00:00:002012Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats.25236446Tsaih SW, Holl K, Jia S, Kaldunski M, Tschannen M, He H, Andrae JW, Li SH, Stoddard A, Wiederhold A, Parrington J, Ruas da Silva M, Galione A, Meigs J, Hoffmann RG, Simpson P, Jacob H, Hessner M, Solberg Woods LCGeneticsTsaih SW, Holl K, Jia S, Kaldunski M, Tschannen M, He H, Andrae JW, Li SH, Stoddard A, Wiederhold A, Parrington J, Ruas da Silva M, Galione A, Meigs J, Hoffmann RG, Simpson P, Jacob H, Hessner M, Solberg Woods LC. Identification of a novel gene for diabetic traits in rats, mice, and humans. Genetics. 2014 Sep; 198(1):17-29.Genetics2014-09-01T00:00:002014Identification of a novel gene for diabetic traits in rats, mice, and humans.26936874Wang X, Johnson AC, Sasser JM, Williams JM, Solberg Woods LC, Garrett MRAmerican journal of physiology. Renal physiologyWang X, Johnson AC, Sasser JM, Williams JM, Solberg Woods LC, Garrett MR. Spontaneous one-kidney rats are more susceptible to develop hypertension by DOCA-NaCl and subsequent kidney injury compared with uninephrectomized rats. Am J Physiol Renal Physiol. 2016 05 01; 310(10):F1054-64.Am J Physiol Renal Physiol2016-03-02T00:00:002016Spontaneous one-kidney rats are more susceptible to develop hypertension by DOCA-NaCl and subsequent kidney injury compared with uninephrectomized rats.2021-06-30NIHSOLBERG WOODS, LEAH CATHERINE2015-09-15Systems Genetics of Adiposity Traits in Outbred RatsR01DK1063862016-05-31NIHSOLBERG WOODS, LEAH CATHERINE2010-08-01Genome-wide fine-mapping of metabolic traits in heterogeneous stock ratsR01DK0889752010-07-31NIHSOLBERG WOODS, LEAH CATHERINE2007-08-01Fine mapping NIDDM QTL 1 using heterogeneous stock ratsK01DK076977Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorAuthorship 554291128834208Holl K, He H, Wedemeyer M, Clopton L, Wert S, Meckes JK, Cheng R, Kastner A, Palmer AA, Redei EE, Solberg Woods LCGenes, brain, and behaviorHoll K, He H, Wedemeyer M, Clopton L, Wert S, Meckes JK, Cheng R, Kastner A, Palmer AA, Redei EE, Solberg Woods LC. Heterogeneous stock rats: a model to study the genetics of despair-like behavior in adolescence. Genes Brain Behav. 2018 02; 17(2):139-148.Genes Brain Behav2017-09-26T00:00:002017Heterogeneous stock rats: a model to study the genetics of despair-like behavior in adolescence.Authorship 5816122Authorship 590677Authorship 5921911Authorship 59775530143073Bukowy JD, Dayton A, Cloutier D, Lombard JH, Solberg Woods LC, Beard DA, Cowley AWKidney internationalBukowy JD, Dayton A, Cloutier D, Lombard JH, Solberg Woods LC, Beard DA, Cowley AW. Do computers dream of electric glomeruli? Kidney Int. 2018 09; 94(3):635.Kidney Int2018-09-01T00:00:002018Do computers dream of electric glomeruli?29750602He H, Holl K, DeBehnke S, Yeo CT, Hansen P, Gebre AK, Leone-Kabler S, Ruas M, Parks JS, Parrington J, Solberg Woods LCPhysiological genomicsHe H, Holl K, DeBehnke S, Yeo CT, Hansen P, Gebre AK, Leone-Kabler S, Ruas M, Parks JS, Parrington J, Solberg Woods LC. Tpcn2 knockout mice have improved insulin sensitivity and are protected against high-fat diet-induced weight gain. Physiol Genomics. 2018 08 01; 50(8):605-614.Physiol Genomics2018-05-11T00:00:002018Tpcn2 knockout mice have improved insulin sensitivity and are protected against high-fat diet-induced weight gain.29193816Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg Woods LCObesity (Silver Spring, Md.)Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg Woods LC. Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats. Obesity (Silver Spring). 2018 01; 26(1):213-222.Obesity (Silver Spring)2017-11-28T00:00:002017Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats.29921718Bukowy JD, Dayton A, Cloutier D, Manis AD, Staruschenko A, Lombard JH, Solberg Woods LC, Beard DA, Cowley AWJournal of the American Society of Nephrology : JASNBukowy JD, Dayton A, Cloutier D, Manis AD, Staruschenko A, Lombard JH, Solberg Woods LC, Beard DA, Cowley AW. Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections. J Am Soc Nephrol. 2018 08; 29(8):2081-2088.J Am Soc Nephrol2018-06-19T00:00:002018Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections.2023-07-31NIHKALIVAS, PETER W2018-09-30The Genetic Basis of Opioid Dependence Vulnerablility in a Rodent ModelU01DA045300Co-Principal Investigator30555441Nagpal R, Wang S, Solberg Woods LC, Seshie O, Chung ST, Shively CA, Register TC, Craft S, McClain DA, Yadav HFrontiers in microbiologyNagpal R, Wang S, Solberg Woods LC, Seshie O, Chung ST, Shively CA, Register TC, Craft S, McClain DA, Yadav H. Comparative Microbiome Signatures and Short-Chain Fatty Acids in Mouse, Rat, Non-human Primate, and Human Feces. Front Microbiol. 2018; 9:2897.Front Microbiol2018-11-30T00:00:002018Comparative Microbiome Signatures and Short-Chain Fatty Acids in Mouse, Rat, Non-human Primate, and Human Feces.20ProfessorAuthorship 645375Authorship 659011Authorship 660203Authorship 66092531228160Solberg Woods LC, Palmer AAMethods in molecular biology (Clifton, N.J.)Solberg Woods LC, Palmer AA. Using Heterogeneous Stocks for Fine-Mapping Genetically Complex Traits. Methods Mol Biol. 2019; 2018:233-247.Methods Mol Biol2019-01-01T00:00:002019Using Heterogeneous Stocks for Fine-Mapping Genetically Complex Traits.30787409Hughson AR, Horvath AP, Holl K, Palmer AA, Solberg Woods LC, Robinson TE, Flagel SBScientific reportsHughson AR, Horvath AP, Holl K, Palmer AA, Solberg Woods LC, Robinson TE, Flagel SB. Incentive salience attribution, "sensation-seeking" and "novelty-seeking" are independent traits in a large sample of male and female heterogeneous stock rats. Sci Rep. 2019 02 20; 9(1):2351.Sci Rep2019-02-20T00:00:002019Incentive salience attribution, "sensation-seeking" and "novelty-seeking" are independent traits in a large sample of male and female heterogeneous stock rats.30584246Wang T, Han W, Chitre AS, Polesskaya O, Solberg Woods LC, Palmer AA, Chen HScientific reportsWang T, Han W, Chitre AS, Polesskaya O, Solberg Woods LC, Palmer AA, Chen H. Social and anxiety-like behaviors contribute to nicotine self-administration in adolescent outbred rats. Sci Rep. 2018 12 24; 8(1):18069.Sci Rep2018-12-24T00:00:002018Social and anxiety-like behaviors contribute to nicotine self-administration in adolescent outbred rats.2024-06-30NIHSOLBERG WOODS, LEAH CATHERINE2019-09-20Systems genetics to identify neuronal genes for diet-induced obesityR01DK120667Principal InvestigatorAuthorship 6852227Authorship 685236Authorship 685244Authorship 68525931932450Kallupi M, Carrette LLG, Kononoff J, Solberg Woods LC, Palmer AA, Schweitzer P, George O, de Guglielmo GProceedings of the National Academy of Sciences of the United States of AmericaKallupi M, Carrette LLG, Kononoff J, Solberg Woods LC, Palmer AA, Schweitzer P, George O, de Guglielmo G. Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2140-2148.Proc Natl Acad Sci U S A2020-01-13T00:00:002020Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats.32687430Deal AW, Seshie O, Lenzo A, Cooper N, Ozimek N, Solberg Woods LCPhysiological genomicsDeal AW, Seshie O, Lenzo A, Cooper N, Ozimek N, Solberg Woods LC. High-fat diet negatively impacts both metabolic and behavioral health in outbred heterogeneous stock rats. Physiol Genomics. 2020 09 01; 52(9):379-390.Physiol Genomics2020-07-20T00:00:002020High-fat diet negatively impacts both metabolic and behavioral health in outbred heterogeneous stock rats.31502538Campus P, Covelo IR, Kim Y, Parsegian A, Kuhn BN, Lopez SA, Neumaier JF, Ferguson SM, Solberg Woods LC, Sarter M, Flagel SBeLifeCampus P, Covelo IR, Kim Y, Parsegian A, Kuhn BN, Lopez SA, Neumaier JF, Ferguson SM, Solberg Woods LC, Sarter M, Flagel SB. The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior in rats. Elife. 2019 09 10; 8.Elife2019-09-10T00:00:002019The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior in rats.32860487Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Bimschleger H, Garcia Martinez A, George T, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin C, St Pierre CL, Tripi JA, Wang T, Chen H, Flagel SB, Meyer P, Richards J, Robinson TE, Palmer AA, Solberg Woods LCObesity (Silver Spring, Md.)Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Bimschleger H, Garcia Martinez A, George T, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin C, St Pierre CL, Tripi JA, Wang T, Chen H, Flagel SB, Meyer P, Richards J, Robinson TE, Palmer AA, Solberg Woods LC. Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose. Obesity (Silver Spring). 2020 10; 28(10):1964-1973.Obesity (Silver Spring)2020-08-29T00:00:002020Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose.Internal Medicine, Endocrinology & MetabolismInternal Medicine, Gerontology & Geriatric MedicineInternal Medicine, Molecular MedicineInternal Medicine, NephrologyPathology, Comparative MedicinePHS-Biostatistics and Data Science (Public Health Sciences)Public Health Sciences (Division of)2ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorD040641Genes & Molecular Sequences321540.929624Quantitative Trait Loci