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research areas: Glutathione Transferase
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Kock, Nancy
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Authorship 11447
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linked author: Townsend, Alan
linked information resource: Cancer chemotherapy and drug metabolism.

Authorship 13132
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author rank in publication: 3
linked author: Townsend, Alan
linked information resource: Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2).

Authorship 14352
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author rank in publication: 4
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linked information resource: Induction of DNA-protein crosslinks by dichloromethane in a V79 cell line transfected with the murine glutathione-S-transferase theta 1 gene.

Authorship 15029
type: Authorship
author rank in publication: 2
linked author: Townsend, Alan
linked information resource: Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1.

Authorship 16937
type: Authorship
author rank in publication: 3
linked author: Townsend, Alan
linked information resource: Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells.

Authorship 17794
type: Authorship
author rank in publication: 4
linked author: Townsend, Alan
linked information resource: Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage.

Authorship 18680
type: Authorship
author rank in publication: 3
linked author: Townsend, Alan
linked information resource: Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane.

Authorship 18953
type: Authorship
author rank in publication: 7
linked author: Townsend, Alan
linked information resource: Oxathiolene oxides: a novel family of compounds that induce ferritin, glutathione S-transferase, and other proteins of the phase II response.

Authorship 1976
type: Authorship
author rank in publication: 2
linked author: Townsend, Alan
linked information resource: Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity.

Authorship 22069
type: Authorship
author rank in publication: 4
linked author: Townsend, Alan
linked information resource: https://profiles.wakehealth.edu/profile/60021

Authorship 23685
type: Authorship
author rank in publication: 3
linked author: Townsend, Alan
linked information resource: Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin.

Authorship 24
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linked author: Townsend, Alan
linked information resource: Journal of Biological Chemistry

Authorship 25053
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author rank in publication: 6
linked author: Townsend, Alan
linked information resource: https://profiles.wakehealth.edu/profile/70640

Authorship 29645
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author rank in publication: 8
linked author: Townsend, Alan
linked information resource: https://profiles.wakehealth.edu/profile/56185

Authorship 3024
type: Authorship
author rank in publication: 5
linked author: Townsend, Alan
linked information resource: Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma.

Authorship 33179
type: Authorship
author rank in publication: 8
linked author: Townsend, Alan
linked information resource: Expression of glutathione S-transferases in fetal lung and liver tissue from parental strains and F1 crosses between C57BL/6 and BALB/c F1 mice following in utero exposure to 3-methylcholanthrene.

Authorship 33337
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author rank in publication: 3
linked author: Townsend, Alan
linked information resource: Nitroalkene fatty acids mediate activation of Nrf2/ARE-dependent and PPAR?-dependent transcription by distinct signaling pathways and with significantly different potencies.

Authorship 33386
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author rank in publication: 8
linked author: Townsend, Alan
linked information resource: Lung tumor promotion by curcumin.

Authorship 4192
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author rank in publication: 6
linked author: Townsend, Alan
linked information resource: Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux.

Authorship 443
type: Authorship
author rank in publication: 6
linked author: Townsend, Alan
linked information resource: Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1.

Authorship 5059
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author rank in publication: 6
linked author: Townsend, Alan
linked information resource: https://profiles.wakehealth.edu/profile/56708

Authorship 54
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linked author: Townsend, Alan
linked information resource: Chemico-Biological Interactions

Authorship 6237
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author rank in publication: 1
linked author: Townsend, Alan
linked information resource: Modeling the metabolic competency of glutathione S-transferases using genetically modified cell lines.

Authorship 6527
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author rank in publication: 6
linked author: Townsend, Alan
linked information resource: Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes.

Authorship 9614
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author rank in publication: 7
linked author: Townsend, Alan
linked information resource: Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression.

Journal of Biological Chemistry
author list: Yohan Suryo, Hawkins, Clare L, Kalinowski, Danuta S., Morrow, Charles S., Townsend, Alan J., Ponka, Prem and Richardson, Des R.
published in: Nitric Oxide Storage and Transport in Cells Are Mediated by Glutathione S-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes
information resource reference: Yohan Suryo, Hawkins, Clare L, Kalinowski, Danuta S., Morrow, Charles S., Townsend, Alan J., Ponka, Prem and Richardson, Des R. Journal of Biological Chemistry. Nitric Oxide Storage and Transport in Cells Are Mediated by Glutathione S-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes. 2011; 287:607-618.
publication date: 2011-11-14T00:00:00
year: 2011
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Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity.
PubMed Identifier: 14569069
author list: Smitherman PK, Townsend AJ, Kute TE, Morrow CS
published in: The Journal of pharmacology and experimental therapeutics
information resource reference: Smitherman PK, Townsend AJ, Kute TE, Morrow CS. Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity. J Pharmacol Exp Ther. 2004 Jan; 308(1):260-7.
journal title abbreviation: J Pharmacol Exp Ther
publication date: 2003-10-20T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
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Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2).
PubMed Identifier: 14979731
author list: Paumi CM, Smitherman PK, Townsend AJ, Morrow CS
published in: Biochemistry
information resource reference: Paumi CM, Smitherman PK, Townsend AJ, Morrow CS. Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2). Biochemistry. 2004 Mar 02; 43(8):2345-52.
journal title abbreviation: Biochemistry
publication date: 2004-03-02T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Cancer chemotherapy and drug metabolism.
PubMed Identifier: 16049130
author list: Riddick DS, Lee C, Ramji S, Chinje EC, Cowen RL, Williams KJ, Patterson AV, Stratford IJ, Morrow CS, Townsend AJ, Jounaidi Y, Chen CS, Su T, Lu H, Schwartz PS, Waxman DJ
published in: Drug metabolism and disposition: the biological fate of chemicals
information resource reference: Riddick DS, Lee C, Ramji S, Chinje EC, Cowen RL, Williams KJ, Patterson AV, Stratford IJ, Morrow CS, Townsend AJ, Jounaidi Y, Chen CS, Su T, Lu H, Schwartz PS, Waxman DJ. Cancer chemotherapy and drug metabolism. Drug Metab Dispos. 2005 Aug; 33(8):1083-96.
journal title abbreviation: Drug Metab Dispos
publication date: 2005-08-01T00:00:00
year: 2005
type: Academic Article
type: Article
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type: Information Resource

https://profiles.wakehealth.edu/profile/56185
PubMed Identifier: 16885195
author list: Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ
published in: Carcinogenesis
information resource reference: Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1. Carcinogenesis. 2007 Jan; 28(1):207-14.
journal title abbreviation: Carcinogenesis
publication date: 2006-08-02T00:00:00
year: 2006
type: Academic Article
type: Article
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type: Information Resource
label: Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.

https://profiles.wakehealth.edu/profile/56708
PubMed Identifier: 17509623
author list: Kushman ME, Kabler SL, Ahmad S, Doehmer J, Morrow CS, Townsend AJ
published in: Mutation research
information resource reference: Kushman ME, Kabler SL, Ahmad S, Doehmer J, Morrow CS, Townsend AJ. Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1. Mutat Res. 2007 Nov 01; 624(1-2):80-7.
journal title abbreviation: Mutat Res
publication date: 2007-04-19T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1.

Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane.
PubMed Identifier: 18204073
author list: Sibhatu MB, Smitherman PK, Townsend AJ, Morrow CS
published in: Carcinogenesis
information resource reference: Sibhatu MB, Smitherman PK, Townsend AJ, Morrow CS. Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane. Carcinogenesis. 2008 Apr; 29(4):807-15.
journal title abbreviation: Carcinogenesis
publication date: 2008-01-19T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma.
PubMed Identifier: 19358561
author list: Bates DJ, Lively MO, Gorczynski MJ, King SB, Townsend AJ, Morrow CS
published in: Biochemistry
information resource reference: Bates DJ, Lively MO, Gorczynski MJ, King SB, Townsend AJ, Morrow CS. Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma. Biochemistry. 2009 May 19; 48(19):4159-69.
journal title abbreviation: Biochemistry
publication date: 2009-05-19T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
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Professor Emeritus of Biochemistry, Winston-Salem
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Assistant Professor of Biochemistry, Winston-Salem
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Associate Professor of Biochemistry, Winston-Salem
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Associate Professor Emeritus of Biochemistry, Winston-Salem
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Professor of Pathology, Winston-Salem - Comparative Medicine
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HR job title: Professor of Pathology, Winston-Salem - Comparative Medicine
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Biochemistry, Winston-Salem
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Pathology, Winston-Salem - Comparative Medicine
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Nitroalkene fatty acids mediate activation of Nrf2/ARE-dependent and PPAR?-dependent transcription by distinct signaling pathways and with significantly different potencies.
PubMed Identifier: 21827153
author list: Bates DJ, Smitherman PK, Townsend AJ, King SB, Morrow CS
published in: Biochemistry
information resource reference: Bates DJ, Smitherman PK, Townsend AJ, King SB, Morrow CS. Nitroalkene fatty acids mediate activation of Nrf2/ARE-dependent and PPAR?-dependent transcription by distinct signaling pathways and with significantly different potencies. Biochemistry. 2011 Sep 13; 50(36):7765-73.
journal title abbreviation: Biochemistry
publication date: 2011-08-17T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

https://profiles.wakehealth.edu/profile/60021
PubMed Identifier: 21925487
author list: Rudd LP, Kabler SL, Morrow CS, Townsend AJ
published in: Chemico-biological interactions
information resource reference: Rudd LP, Kabler SL, Morrow CS, Townsend AJ. Enhanced glutathione depletion, protein adduct formation, and cytotoxicity following exposure to 4-hydroxy-2-nonenal (HNE) in cells expressing human multidrug resistance protein-1 (MRP1) together with human glutathione S-transferase-M1 (GSTM1). Chem Biol Interact. 2011 Nov 15; 194(2-3):113-9.
journal title abbreviation: Chem Biol Interact
publication date: 2011-09-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Enhanced glutathione depletion, protein adduct formation, and cytotoxicity following exposure to 4-hydroxy-2-nonenal (HNE) in cells expressing human multidrug resistance protein-1 (MRP1) together with human glutathione S-transferase-M1 (GSTM1).

Modeling the metabolic competency of glutathione S-transferases using genetically modified cell lines.
PubMed Identifier: 12505323
author list: Townsend AJ, Kabler SL, Doehmer J, Morrow CS
published in: Toxicology
information resource reference: Townsend AJ, Kabler SL, Doehmer J, Morrow CS. Modeling the metabolic competency of glutathione S-transferases using genetically modified cell lines. Toxicology. 2002 Dec 27; 181-182:265-9.
journal title abbreviation: Toxicology
publication date: 2002-12-27T00:00:00
year: 2002
type: Academic Article
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Oxathiolene oxides: a novel family of compounds that induce ferritin, glutathione S-transferase, and other proteins of the phase II response.
PubMed Identifier: 12694867
author list: Pietsch EC, Hurley AL, Scott EE, Duckworth BP, Welker ME, Leone-Kabler S, Townsend AJ, Torti FM, Torti SV
published in: Biochemical pharmacology
information resource reference: Pietsch EC, Hurley AL, Scott EE, Duckworth BP, Welker ME, Leone-Kabler S, Townsend AJ, Torti FM, Torti SV. Oxathiolene oxides: a novel family of compounds that induce ferritin, glutathione S-transferase, and other proteins of the phase II response. Biochem Pharmacol. 2003 Apr 15; 65(8):1261-9.
journal title abbreviation: Biochem Pharmacol
publication date: 2003-04-15T00:00:00
year: 2003
type: Academic Article
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Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage.
PubMed Identifier: 12706498
author list: Pappa A, Chen C, Koutalos Y, Townsend AJ, Vasiliou V
published in: Free radical biology & medicine
information resource reference: Pappa A, Chen C, Koutalos Y, Townsend AJ, Vasiliou V. Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage. Free Radic Biol Med. 2003 May 01; 34(9):1178-89.
journal title abbreviation: Free Radic Biol Med
publication date: 2003-05-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells.
PubMed Identifier: 12731885
author list: Paumi CM, Wright M, Townsend AJ, Morrow CS
published in: Biochemistry
information resource reference: Paumi CM, Wright M, Townsend AJ, Morrow CS. Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. Biochemistry. 2003 May 13; 42(18):5429-37.
journal title abbreviation: Biochemistry
publication date: 2003-05-13T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1.
PubMed Identifier: 15766272
author list: Peklak-Scott C, Townsend AJ, Morrow CS
published in: Biochemistry
information resource reference: Peklak-Scott C, Townsend AJ, Morrow CS. Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1. Biochemistry. 2005 Mar 22; 44(11):4426-33.
journal title abbreviation: Biochemistry
publication date: 2005-03-22T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux.
PubMed Identifier: 16434618
author list: Morrow CS, Peklak-Scott C, Bishwokarma B, Kute TE, Smitherman PK, Townsend AJ
published in: Molecular pharmacology
information resource reference: Morrow CS, Peklak-Scott C, Bishwokarma B, Kute TE, Smitherman PK, Townsend AJ. Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux. Mol Pharmacol. 2006 Apr; 69(4):1499-505.
journal title abbreviation: Mol Pharmacol
publication date: 2006-01-24T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression of glutathione S-transferases in fetal lung and liver tissue from parental strains and F1 crosses between C57BL/6 and BALB/c F1 mice following in utero exposure to 3-methylcholanthrene.
PubMed Identifier: 16678797
author list: Xu M, Moore JE, Leone-Kabler S, McCoy TP, Swank A, Nelson GB, Ross JA, Townsend AJ, Miller MS
published in: Biochemical pharmacology
information resource reference: Xu M, Moore JE, Leone-Kabler S, McCoy TP, Swank A, Nelson GB, Ross JA, Townsend AJ, Miller MS. Expression of glutathione S-transferases in fetal lung and liver tissue from parental strains and F1 crosses between C57BL/6 and BALB/c F1 mice following in utero exposure to 3-methylcholanthrene. Biochem Pharmacol. 2006 Jun 28; 72(1):115-23.
journal title abbreviation: Biochem Pharmacol
publication date: 2006-03-18T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Induction of DNA-protein crosslinks by dichloromethane in a V79 cell line transfected with the murine glutathione-S-transferase theta 1 gene.
PubMed Identifier: 16765633
author list: Hu Y, Kabler SL, Tennant AH, Townsend AJ, Kligerman AD
published in: Mutation research
information resource reference: Hu Y, Kabler SL, Tennant AH, Townsend AJ, Kligerman AD. Induction of DNA-protein crosslinks by dichloromethane in a V79 cell line transfected with the murine glutathione-S-transferase theta 1 gene. Mutat Res. 2006 Sep 05; 607(2):231-9.
journal title abbreviation: Mutat Res
publication date: 2006-06-12T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1.
PubMed Identifier: 17525473
author list: Kushman ME, Kabler SL, Ahmad S, Doehmer J, Morrow CS, Townsend AJ
published in: Toxicological sciences : an official journal of the Society of Toxicology
information resource reference: Kushman ME, Kabler SL, Ahmad S, Doehmer J, Morrow CS, Townsend AJ. Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1. Toxicol Sci. 2007 Sep; 99(1):51-7.
journal title abbreviation: Toxicol Sci
publication date: 2007-05-24T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin.
PubMed Identifier: 18852128
author list: Peklak-Scott C, Smitherman PK, Townsend AJ, Morrow CS
published in: Molecular cancer therapeutics
information resource reference: Peklak-Scott C, Smitherman PK, Townsend AJ, Morrow CS. Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin. . 2008 Oct; 7(10):3247-55.
publication date: 2008-10-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression.
PubMed Identifier: 18992797
author list: Ahmad S, Kabler SL, Rudd L, Amin S, Doehmer J, Morrow CS, Townsend AJ
published in: Toxicology letters
information resource reference: Ahmad S, Kabler SL, Rudd L, Amin S, Doehmer J, Morrow CS, Townsend AJ. Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression. Toxicol Lett. 2008 Dec 15; 183(1-3):99-104.
journal title abbreviation: Toxicol Lett
publication date: 2008-10-22T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

https://profiles.wakehealth.edu/profile/70640
PubMed Identifier: 19330882
author list: Kabler SL, Seidel A, Jacob J, Doehmer J, Morrow CS, Townsend AJ
published in: Chemico-biological interactions
information resource reference: Kabler SL, Seidel A, Jacob J, Doehmer J, Morrow CS, Townsend AJ. Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1. Chem Biol Interact. 2009 May 15; 179(2-3):240-6.
journal title abbreviation: Chem Biol Interact
publication date: 2009-05-15T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.

Lung tumor promotion by curcumin.
PubMed Identifier: 19359593
author list: Dance-Barnes ST, Kock ND, Moore JE, Lin EY, Mosley LJ, D'Agostino RB, McCoy TP, Townsend AJ, Miller MS
published in: Carcinogenesis
information resource reference: Dance-Barnes ST, Kock ND, Moore JE, Lin EY, Mosley LJ, D'Agostino RB, McCoy TP, Townsend AJ, Miller MS. Lung tumor promotion by curcumin. Carcinogenesis. 2009 Jun; 30(6):1016-23.
journal title abbreviation: Carcinogenesis
publication date: 2009-04-09T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Chemico-Biological Interactions
author list: Rudd, Lisa P., Kabler, Sandra L., Morrow, Charles S. and Townsend, Alan J.
published in: Cytotoxicity, Glutathione Depletion and HNE-protein Adduct Formation by 4-hydroxy-2-nonenal (HNE) in cell lines expressing GSTM1 and or MRP1/MRP2.
information resource reference: Rudd, Lisa P., Kabler, Sandra L., Morrow, Charles S. and Townsend, Alan J. Chemico-Biological Interactions. Cytotoxicity, Glutathione Depletion and HNE-protein Adduct Formation by 4-hydroxy-2-nonenal (HNE) in cell lines expressing GSTM1 and or MRP1/MRP2. 2011; 194:113-119.
publication date: 2011-09-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes.
PubMed Identifier: 22084240
author list: Lok HC, Rahmanto YS, Hawkins CL, Kalinowski DS, Morrow CS, Townsend AJ, Ponka P, Richardson DR
published in: The Journal of biological chemistry
information resource reference: Lok HC, Rahmanto YS, Hawkins CL, Kalinowski DS, Morrow CS, Townsend AJ, Ponka P, Richardson DR. Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes. J Biol Chem. 2012 Jan 02; 287(1):607-618.
journal title abbreviation: J Biol Chem
publication date: 2011-11-14T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Benzo(a)pyrene
MeSH DescriptorUI: D001564
MeSH semantic group name: Chemicals & Drugs
number of authors: 2
number of publications: 5
uniqueness weight: 0.994652
type: Concept

Dihydroxydihydrobenzopyrenes
MeSH DescriptorUI: D004101
MeSH semantic group name: Chemicals & Drugs
number of authors: 1
number of publications: 3
uniqueness weight: 0.995872
type: Concept

Cytochrome P-450 CYP1A1
MeSH DescriptorUI: D019363
MeSH semantic group name: Chemicals & Drugs
number of authors: 8
number of publications: 13
uniqueness weight: 0.990161
type: Concept

Glutathione Transferase
MeSH DescriptorUI: D005982
MeSH semantic group name: Chemicals & Drugs
number of authors: 15
number of publications: 27
uniqueness weight: 0.98843
type: Concept