Childers, Steven
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selected publications: Authorship 2831
selected publications: Authorship 9935
selected publications: Authorship 29155
research areas: GTP-Binding Proteins
research areas: Brain
research areas: Heroin
research areas: Dopamine Plasma Membrane Transport Proteins
research areas: Membrane Transport Proteins
mailing address: https://profiles.wakehealth.edu/profile/17751
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Dopamine Plasma Membrane Transport Proteins
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number of authors: 23
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Bonkovsky, Herbert
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Authorship 40168
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author rank in publication: 4
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linked information resource: Changes in dopamine transporter binding in nucleus accumbens following chronic self-administration cocaine: heroin combinations.

Changes in dopamine transporter binding in nucleus accumbens following chronic self-administration cocaine: heroin combinations.
PubMed Identifier: 24916769
author list: Pattison LP, McIntosh S, Sexton T, Childers SR, Hemby SE
published in: Synapse (New York, N.Y.)
information resource reference: Pattison LP, McIntosh S, Sexton T, Childers SR, Hemby SE. Changes in dopamine transporter binding in nucleus accumbens following chronic self-administration cocaine: heroin combinations. Synapse. 2014 Oct; 68(10):437-44.
journal title abbreviation: Synapse
publication date: 2014-06-19T00:00:00
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Wake Forest School of Medicine
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Roberts, David
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Eisenach, James
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Howlett, Allyn
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Tobin, Joseph
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Gallagher, Patricia
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person in primary position: Professor of Surgery, Winston-Salem - Hypertension
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Sherertz, Robert
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person in primary position: Professor Emeritus of Internal Medicine, Winston-Salem - Infectious Disease
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Martin, Thomas
first name: Thomas
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person in primary position: Professor of Anesthesiology, Winston-Salem - Basic Sciences/Translational Research
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Authorship 42362
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author rank in publication: 6
linked author: Childers, Steven
linked information resource: Chronic baclofen desensitizes GABA(B)-mediated G-protein activation and stimulates phosphorylation of kinases in mesocorticolimbic rat brain.

Chronic baclofen desensitizes GABA(B)-mediated G-protein activation and stimulates phosphorylation of kinases in mesocorticolimbic rat brain.
PubMed Identifier: 25724082
author list: Keegan BM, Beveridge TJ, Pezor JJ, Xiao R, Sexton T, Childers SR, Howlett AC
published in: Neuropharmacology
information resource reference: Keegan BM, Beveridge TJ, Pezor JJ, Xiao R, Sexton T, Childers SR, Howlett AC. Chronic baclofen desensitizes GABA(B)-mediated G-protein activation and stimulates phosphorylation of kinases in mesocorticolimbic rat brain. Neuropharmacology. 2015 Aug; 95:492-502.
journal title abbreviation: Neuropharmacology
publication date: 2015-02-25T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 46309
type: Authorship
author rank in publication: 4
linked author: Childers, Steven
linked information resource: Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding.

Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding.
PubMed Identifier: 25749646
author list: McIntosh S, Sexton T, Pattison LP, Childers SR, Hemby SE
published in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
information resource reference: McIntosh S, Sexton T, Pattison LP, Childers SR, Hemby SE. Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding. J Neuroimmune Pharmacol. 2015 Sep; 10(3):493-505.
journal title abbreviation: J Neuroimmune Pharmacol
publication date: 2015-03-10T00:00:00
year: 2015
type: Academic Article
type: Article
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Said, Neveen
first name: Neveen
last name: Said
full name: Neveen Said PhD; MD
has faculty rank: Associate Professor
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Person ID: 1834
person in primary position: Associate Professor of Cancer Biology, Winston-Salem
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Deep, Gagan
first name: Gagan
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has faculty rank: Associate Professor
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Person ID: 1924
person in primary position: Professor of Internal Medicine, Winston-Salem - Gerontology & Geriatrics
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Authorship 10064
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author rank in publication: 4
linked author: Childers, Steven
linked information resource: Differential regional effects of methadone maintenance compared to heroin dependence on mu-opioid receptor desensitization in rat brain.

Authorship 10954
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author rank in publication: 3
linked author: Childers, Steven
linked information resource: Mechanisms of mu opioid receptor/G-protein desensitization in brain by chronic heroin administration.

Authorship 12455
type: Authorship
author rank in publication: 4
linked author: Childers, Steven
linked information resource: Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortex.

Authorship 12775
type: Authorship
author rank in publication: 3
linked author: Childers, Steven
linked information resource: Cannabinoid physiology and pharmacology: 30 years of progress.

Authorship 36183
type: Authorship
author rank in publication: 2
linked author: Childers, Steven
linked information resource: Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation.

Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation.
PubMed Identifier: 24204784
author list: Antonio T, Childers SR, Rothman RB, Dersch CM, King C, Kuehne M, Bornmann WG, Eshleman AJ, Janowsky A, Simon ER, Reith ME, Alper K
published in: PloS one
information resource reference: Antonio T, Childers SR, Rothman RB, Dersch CM, King C, Kuehne M, Bornmann WG, Eshleman AJ, Janowsky A, Simon ER, Reith ME, Alper K. Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation. PLoS One. 2013; 8(10):e77262.
journal title abbreviation: PLoS One
publication date: 2013-10-16T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 14594
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author rank in publication: 4
linked author: Childers, Steven
linked information resource: Time-dependent changes in receptor/G-protein coupling in rat brain following chronic monoamine transporter blockade.

Authorship 14695
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author rank in publication: 3
linked author: Childers, Steven
linked information resource: Dopamine uptake changes associated with cocaine self-administration.

Authorship 15854
type: Authorship
author rank in publication: 4
linked author: Childers, Steven
linked information resource: Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.

Authorship 16041
type: Authorship
author rank in publication: 2
linked author: Childers, Steven
linked information resource: Role of adenosine receptors in spinal G-protein activation after peripheral nerve injury.

Authorship 17583
type: Authorship
author rank in publication: 5
linked author: Childers, Steven
linked information resource: Spinal nerve ligation increases alpha2-adrenergic receptor G-protein coupling in the spinal cord.

Authorship 19281
type: Authorship
author rank in publication: 1
linked author: Childers, Steven
linked information resource: Activation of G-proteins in brain by endogenous and exogenous cannabinoids.

Authorship 20328
type: Authorship
author rank in publication: 5
linked author: Childers, Steven
linked information resource: Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids.

Authorship 20485
type: Authorship
author rank in publication: 4
linked author: Childers, Steven
linked information resource: Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain.

Authorship 20505
type: Authorship
author rank in publication: 3
linked author: Childers, Steven
linked information resource: Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats.

Authorship 20928
type: Authorship
author rank in publication: 4
linked author: Childers, Steven
linked information resource: Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain.

Authorship 23362
type: Authorship
author rank in publication: 3
linked author: Childers, Steven
linked information resource: Distribution of ORL-1 receptor binding and receptor-activated G-proteins in rat forebrain and their experimental localization in anterior cingulate cortex.

Authorship 2831
type: Authorship
author rank in publication: 5
linked author: Childers, Steven
linked information resource: Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters.

Authorship 29155
type: Authorship
author rank in publication: 2
linked author: Childers, Steven
linked information resource: Neuroanatomical localization of receptor-activated G proteins in brain.

Authorship 29948
type: Authorship
author rank in publication: 4
linked author: Childers, Steven
linked information resource: Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain.

Authorship 30494
type: Authorship
author rank in publication: 5
linked author: Childers, Steven
linked information resource: Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites.

Authorship 3063
type: Authorship
author rank in publication: 5
linked author: Childers, Steven
linked information resource: The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines.

Authorship 30867
type: Authorship
author rank in publication: 3
linked author: Childers, Steven
linked information resource: Endocannabinoid tone versus constitutive activity of cannabinoid receptors.

Authorship 32367
type: Authorship
author rank in publication: 3
linked author: Childers, Steven
linked information resource: Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism.

Authorship 33623
type: Authorship
author rank in publication: 5
linked author: Childers, Steven
linked information resource: In vivo characterization of a novel phenylisothiocyanate tropane analog at monoamine transporters in rat brain.

Authorship 5371
type: Authorship
author rank in publication: 6
linked author: Childers, Steven
linked information resource: Involvement of the lateral amygdala in the antiallodynic and reinforcing effects of heroin in rats after peripheral nerve injury.

Authorship 7255
type: Authorship
author rank in publication: 3
linked author: Childers, Steven
linked information resource: Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and d opioid systems.

Authorship 7651
type: Authorship
author rank in publication: 1
linked author: Childers, Steven
linked information resource: Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain.

Authorship 9529
type: Authorship
author rank in publication: 3
linked author: Childers, Steven
linked information resource: 1-Naphthyl and 4-indolyl arylalkylamines as selective monoamine reuptake inhibitors.

Authorship 9935
type: Authorship
author rank in publication: 4
linked author: Childers, Steven
linked information resource: Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding.

Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding.
PubMed Identifier: 11753009
author list: Bantel C, Tobin JR, Li X, Childers SR, Chen SR, Eisenach JC
published in: Anesthesiology
information resource reference: Bantel C, Tobin JR, Li X, Childers SR, Chen SR, Eisenach JC. Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding. Anesthesiology. 2002 Jan; 96(1):103-8.
journal title abbreviation: Anesthesiology
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters.
PubMed Identifier: 11958976
author list: Davies HM, Ren P, Kong NX, Sexton T, Childers SR
published in: Bioorganic & medicinal chemistry letters
information resource reference: Davies HM, Ren P, Kong NX, Sexton T, Childers SR. Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters. Bioorg Med Chem Lett. 2002 Mar 25; 12(6):845-7.
journal title abbreviation: Bioorg Med Chem Lett
publication date: 2002-03-25T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortex.
PubMed Identifier: 12215369
author list: Sim-Selley LJ, Vogt LJ, Vogt BA, Childers SR
published in: Life sciences
information resource reference: Sim-Selley LJ, Vogt LJ, Vogt BA, Childers SR. Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortex. Life Sci. 2002 Sep 27; 71(19):2217-26.
journal title abbreviation: Life Sci
publication date: 2002-09-27T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Distribution of ORL-1 receptor binding and receptor-activated G-proteins in rat forebrain and their experimental localization in anterior cingulate cortex.
PubMed Identifier: 12842128
author list: Sim-Selley LJ, Vogt LJ, Childers SR, Vogt BA
published in: Neuropharmacology
information resource reference: Sim-Selley LJ, Vogt LJ, Childers SR, Vogt BA. Distribution of ORL-1 receptor binding and receptor-activated G-proteins in rat forebrain and their experimental localization in anterior cingulate cortex. Neuropharmacology. 2003 Aug; 45(2):220-30.
journal title abbreviation: Neuropharmacology
publication date: 2003-08-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites.
PubMed Identifier: 15026075
author list: Davies HM, Hopper DW, Hansen T, Liu Q, Childers SR
published in: Bioorganic & medicinal chemistry letters
information resource reference: Davies HM, Hopper DW, Hansen T, Liu Q, Childers SR. Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites. Bioorg Med Chem Lett. 2004 Apr 05; 14(7):1799-802.
journal title abbreviation: Bioorg Med Chem Lett
publication date: 2004-04-05T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain.
PubMed Identifier: 15087633
author list: Li X, Bantel C, Conklin D, Childers SR, Eisenach JC
published in: Anesthesiology
information resource reference: Li X, Bantel C, Conklin D, Childers SR, Eisenach JC. Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain. Anesthesiology. 2004 Apr; 100(4):956-61.
journal title abbreviation: Anesthesiology
publication date: 2004-04-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids.
PubMed Identifier: 15165836
author list: Breivogel CS, Walker JM, Huang SM, Roy MB, Childers SR
published in: Neuropharmacology
information resource reference: Breivogel CS, Walker JM, Huang SM, Roy MB, Childers SR. Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids. Neuropharmacology. 2004 Jul; 47(1):81-91.
journal title abbreviation: Neuropharmacology
publication date: 2004-07-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Cannabinoid physiology and pharmacology: 30 years of progress.
PubMed Identifier: 15464149
author list: Howlett AC, Breivogel CS, Childers SR, Deadwyler SA, Hampson RE, Porrino LJ
published in: Neuropharmacology
information resource reference: Howlett AC, Breivogel CS, Childers SR, Deadwyler SA, Hampson RE, Porrino LJ. Cannabinoid physiology and pharmacology: 30 years of progress. Neuropharmacology. 2004; 47 Suppl 1:345-58.
journal title abbreviation: Neuropharmacology
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Time-dependent changes in receptor/G-protein coupling in rat brain following chronic monoamine transporter blockade.
PubMed Identifier: 15644432
author list: O'Connor KA, Porrino LJ, Davies HM, Childers SR
published in: The Journal of pharmacology and experimental therapeutics
information resource reference: O'Connor KA, Porrino LJ, Davies HM, Childers SR. Time-dependent changes in receptor/G-protein coupling in rat brain following chronic monoamine transporter blockade. J Pharmacol Exp Ther. 2005 May; 313(2):510-7.
journal title abbreviation: J Pharmacol Exp Ther
publication date: 2005-01-11T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Spinal nerve ligation increases alpha2-adrenergic receptor G-protein coupling in the spinal cord.
PubMed Identifier: 15748875
author list: Bantel C, Eisenach JC, Duflo F, Tobin JR, Childers SR
published in: Brain research
information resource reference: Bantel C, Eisenach JC, Duflo F, Tobin JR, Childers SR. Spinal nerve ligation increases alpha2-adrenergic receptor G-protein coupling in the spinal cord. Brain Res. 2005 Mar 15; 1038(1):76-82.
journal title abbreviation: Brain Res
publication date: 2005-03-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain.
PubMed Identifier: 15836630
author list: Childers SR, Li X, Xiao R, Eisenach JC
published in: Journal of neurochemistry
information resource reference: Childers SR, Li X, Xiao R, Eisenach JC. Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain. J Neurochem. 2005 May; 93(3):715-23.
journal title abbreviation: J Neurochem
publication date: 2005-05-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of G-proteins in brain by endogenous and exogenous cannabinoids.
PubMed Identifier: 16584117
author list: Childers SR
published in: The AAPS journal
information resource reference: Childers SR. Activation of G-proteins in brain by endogenous and exogenous cannabinoids. AAPS J. 2006 Mar 10; 8(1):E112-7.
journal title abbreviation: AAPS J
publication date: 2006-03-10T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential regional effects of methadone maintenance compared to heroin dependence on mu-opioid receptor desensitization in rat brain.
PubMed Identifier: 17152089
author list: Martin TJ, Kahn WR, Xiao R, Childers SR
published in: Synapse (New York, N.Y.)
information resource reference: Martin TJ, Kahn WR, Xiao R, Childers SR. Differential regional effects of methadone maintenance compared to heroin dependence on mu-opioid receptor desensitization in rat brain. Synapse. 2007 Mar; 61(3):176-84.
journal title abbreviation: Synapse
publication date: 2007-03-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

In vivo characterization of a novel phenylisothiocyanate tropane analog at monoamine transporters in rat brain.
PubMed Identifier: 18492949
author list: Murthy V, Martin TJ, Kim S, Davies HM, Childers SR
published in: The Journal of pharmacology and experimental therapeutics
information resource reference: Murthy V, Martin TJ, Kim S, Davies HM, Childers SR. In vivo characterization of a novel phenylisothiocyanate tropane analog at monoamine transporters in rat brain. J Pharmacol Exp Ther. 2008 Aug; 326(2):587-95.
journal title abbreviation: J Pharmacol Exp Ther
publication date: 2008-05-20T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor Emeritus of Anesthesiology, Winston-Salem
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Professor of Anesthesiology, Winston-Salem - Basic Sciences/Translational Research
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Professor of Anesthesiology, Winston-Salem - Basic Sciences/Translational Research
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Associate Professor of Cancer Biology, Winston-Salem
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position in department: Cancer Biology, Winston-Salem
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HR job title: Associate Professor of Cancer Biology, Winston-Salem
position in organization: Wake Forest School of Medicine

Professor Emeritus in Internal Medicine, Winston-Salem - Gastroenterology
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position in department: Internal Medicine, Winston-Salem - Gastroenterology
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HR job title: Professor Emeritus in Internal Medicine, Winston-Salem - Gastroenterology
position in organization: Wake Forest School of Medicine

Professor of Internal Medicine, Winston-Salem - Gerontology & Geriatrics
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position in department: Internal Medicine, Winston-Salem - Gerontology & Geriatrics
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HR job title: Professor of Internal Medicine, Winston-Salem - Gerontology & Geriatrics
position in organization: Wake Forest School of Medicine

Professor Emeritus of Internal Medicine, Winston-Salem - Infectious Disease
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position in department: Internal Medicine, Winston-Salem - Infectious Disease
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HR job title: Professor Emeritus of Internal Medicine, Winston-Salem - Infectious Disease
position in organization: Wake Forest School of Medicine

Professor of Surgery, Winston-Salem - Hypertension
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position in department: Surgery, Winston-Salem - Hypertension
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HR job title: Professor of Surgery, Winston-Salem - Hypertension
position in organization: Wake Forest School of Medicine

Professor Emeritus of Translational Neuroscience, Winston-Salem
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position in department: Translational Neuroscience, Winston-Salem
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HR job title: Professor Emeritus of Translational Neuroscience, Winston-Salem
position in organization: Wake Forest School of Medicine

Professor Emeritus of Translational Neuroscience, Winston-Salem
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position in department: Translational Neuroscience, Winston-Salem
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Professor of Translational Neuroscience, Winston-Salem
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position in department: Translational Neuroscience, Winston-Salem
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Anesthesiology, Winston-Salem
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Anesthesiology, Winston-Salem - Basic Sciences/Translational Research
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Cancer Biology, Winston-Salem
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Internal Medicine, Winston-Salem - Gastroenterology
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Internal Medicine, Winston-Salem - Gerontology & Geriatrics
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Internal Medicine, Winston-Salem - Infectious Disease
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Surgery, Winston-Salem - Hypertension
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Translational Neuroscience, Winston-Salem
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Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats.
PubMed Identifier: 22085876
author list: Nieves-Martinez E, Haynes K, Childers SR, Sonntag WE, Nicolle MM
published in: Behavioural brain research
information resource reference: Nieves-Martinez E, Haynes K, Childers SR, Sonntag WE, Nicolle MM. Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats. Behav Brain Res. 2012 Feb 01; 227(1):258-64.
journal title abbreviation: Behav Brain Res
publication date: 2011-11-07T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Neuroanatomical localization of receptor-activated G proteins in brain.
PubMed Identifier: 11771400
author list: Sim-Selley LJ, Childers SR
published in: Methods in enzymology
information resource reference: Sim-Selley LJ, Childers SR. Neuroanatomical localization of receptor-activated G proteins in brain. Methods Enzymol. 2002; 344:42-58.
journal title abbreviation: Methods Enzymol
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of adenosine receptors in spinal G-protein activation after peripheral nerve injury.
PubMed Identifier: 12170058
author list: Bantel C, Childers SR, Eisenach JC
published in: Anesthesiology
information resource reference: Bantel C, Childers SR, Eisenach JC. Role of adenosine receptors in spinal G-protein activation after peripheral nerve injury. Anesthesiology. 2002 Jun; 96(6):1443-9.
journal title abbreviation: Anesthesiology
publication date: 2002-06-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain.
PubMed Identifier: 15617728
author list: O'Connor KA, Gregg TC, Davies HM, Childers SR
published in: Neuropharmacology
information resource reference: O'Connor KA, Gregg TC, Davies HM, Childers SR. Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain. Neuropharmacology. 2005 Jan; 48(1):62-71.
journal title abbreviation: Neuropharmacology
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of mu opioid receptor/G-protein desensitization in brain by chronic heroin administration.
PubMed Identifier: 15890372
author list: Maher CE, Martin TJ, Childers SR
published in: Life sciences
information resource reference: Maher CE, Martin TJ, Childers SR. Mechanisms of mu opioid receptor/G-protein desensitization in brain by chronic heroin administration. Life Sci. 2005 Jul 22; 77(10):1140-54.
journal title abbreviation: Life Sci
publication date: 2005-07-22T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines.
PubMed Identifier: 16165350
author list: Lapa GB, Byrd GD, Lapa AA, Budygin EA, Childers SR, Jones SR, Harp JJ
published in: Bioorganic & medicinal chemistry letters
information resource reference: Lapa GB, Byrd GD, Lapa AA, Budygin EA, Childers SR, Jones SR, Harp JJ. The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines. Bioorg Med Chem Lett. 2005 Nov 15; 15(22):4915-8.
journal title abbreviation: Bioorg Med Chem Lett
publication date: 2005-11-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.
PubMed Identifier: 17001280
author list: Martin TJ, Eisenach JC, Misler J, Childers SR
published in: Neuroreport
information resource reference: Martin TJ, Eisenach JC, Misler J, Childers SR. Chronic activation of spinal adenosine A1 receptors results in hypersensitivity. Neuroreport. 2006 Oct 23; 17(15):1619-22.
journal title abbreviation: Neuroreport
publication date: 2006-10-23T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism.
PubMed Identifier: 17457135
author list: Clayton BA, Hayashida K, Childers SR, Xiao R, Eisenach JC
published in: Anesthesiology
information resource reference: Clayton BA, Hayashida K, Childers SR, Xiao R, Eisenach JC. Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism. Anesthesiology. 2007 May; 106(5):1019-25.
journal title abbreviation: Anesthesiology
publication date: 2007-05-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain.
PubMed Identifier: 17540345
author list: Murthy V, Davies HM, Hedley SJ, Childers SR
published in: Biochemical pharmacology
information resource reference: Murthy V, Davies HM, Hedley SJ, Childers SR. Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain. Biochem Pharmacol. 2007 Jul 15; 74(2):336-44.
journal title abbreviation: Biochem Pharmacol
publication date: 2007-04-27T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Dopamine uptake changes associated with cocaine self-administration.
PubMed Identifier: 18923398
author list: Oleson EB, Talluri S, Childers SR, Smith JE, Roberts DC, Bonin KD, Budygin EA
published in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
information resource reference: Oleson EB, Talluri S, Childers SR, Smith JE, Roberts DC, Bonin KD, Budygin EA. Dopamine uptake changes associated with cocaine self-administration. Neuropsychopharmacology. 2009 Apr; 34(5):1174-84.
journal title abbreviation: Neuropsychopharmacology
publication date: 2008-10-15T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

1-Naphthyl and 4-indolyl arylalkylamines as selective monoamine reuptake inhibitors.
PubMed Identifier: 19038547
author list: Manning JR, Sexton T, Childers SR, Davies HM
published in: Bioorganic & medicinal chemistry letters
information resource reference: Manning JR, Sexton T, Childers SR, Davies HM. 1-Naphthyl and 4-indolyl arylalkylamines as selective monoamine reuptake inhibitors. Bioorg Med Chem Lett. 2009 Jan 01; 19(1):58-61.
journal title abbreviation: Bioorg Med Chem Lett
publication date: 2008-11-13T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Involvement of the lateral amygdala in the antiallodynic and reinforcing effects of heroin in rats after peripheral nerve injury.
PubMed Identifier: 21293255
author list: Martin TJ, Buechler NL, Kim SA, Ewan EE, Xiao R, Childers SR
published in: Anesthesiology
information resource reference: Martin TJ, Buechler NL, Kim SA, Ewan EE, Xiao R, Childers SR. Involvement of the lateral amygdala in the antiallodynic and reinforcing effects of heroin in rats after peripheral nerve injury. Anesthesiology. 2011 Mar; 114(3):633-42.
journal title abbreviation: Anesthesiology
publication date: 2011-03-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Endocannabinoid tone versus constitutive activity of cannabinoid receptors.
PubMed Identifier: 21545414
author list: Howlett AC, Reggio PH, Childers SR, Hampson RE, Ulloa NM, Deutsch DG
published in: British journal of pharmacology
information resource reference: Howlett AC, Reggio PH, Childers SR, Hampson RE, Ulloa NM, Deutsch DG. Endocannabinoid tone versus constitutive activity of cannabinoid receptors. Br J Pharmacol. 2011 Aug; 163(7):1329-43.
journal title abbreviation: Br J Pharmacol
publication date: 2011-08-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and d opioid systems.
PubMed Identifier: 23286559
author list: Blume LC, Bass CE, Childers SR, Dalton GD, Roberts DC, Richardson JM, Xiao R, Selley DE, Howlett AC
published in: Journal of neurochemistry
information resource reference: Blume LC, Bass CE, Childers SR, Dalton GD, Roberts DC, Richardson JM, Xiao R, Selley DE, Howlett AC. Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and d opioid systems. J Neurochem. 2013 Mar; 124(6):808-20.
journal title abbreviation: J Neurochem
publication date: 2013-01-31T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane Transport Proteins
MeSH DescriptorUI: D026901
MeSH semantic group name: Chemicals & Drugs
number of authors: 28
number of publications: 41
uniqueness weight: 0.97444
type: Concept

Brain
MeSH DescriptorUI: D001921
MeSH semantic group name: Anatomy
number of authors: 231
number of publications: 1031
uniqueness weight: 0.597538
type: Concept

Heroin
MeSH DescriptorUI: D003932
MeSH semantic group name: Chemicals & Drugs
number of authors: 8
number of publications: 33
uniqueness weight: 0.976445
type: Concept

GTP-Binding Proteins
MeSH DescriptorUI: D019204
MeSH semantic group name: Chemicals & Drugs
number of authors: 18
number of publications: 40
uniqueness weight: 0.973065
type: Concept