D014763Chemicals & DrugsD12.776.964.970.880.9407340.966802Viral Matrix Proteinsprns:emailEncryptedemail addressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson5.941790.02494527research area of0.4877690.066995431subject area for24252853Blackham AU, Northrup SA, Willingham M, Sirintrapun J, Russell GB, Lyles DS, Stewart JHThe Journal of surgical researchBlackham AU, Northrup SA, Willingham M, Sirintrapun J, Russell GB, Lyles DS, Stewart JH. Molecular determinants of susceptibility to oncolytic vesicular stomatitis virus in pancreatic adenocarcinoma. J Surg Res. 2014 Apr; 187(2):412-26.J Surg Res2013-10-21T00:00:002013Molecular determinants of susceptibility to oncolytic vesicular stomatitis virus in pancreatic adenocarcinoma.BiochemistryMicrobiology and ImmunologyWake Forest School of MedicineDouglasLylesDouglas S. Lyles PhD36.08919100000000-80.26677800000000233Lyles, DouglasProfessorMarthaAlexander-Miller4MC38pybvDqOTrPFxxARchSSnXEUZ/41PeKUY3jDi/Sa+yrfEF0=Martha A. Alexander-Miller PhD36.09032400000000-80.26649100000000603Alexander-Miller, MarthaProfessorMarlenaWestcottMarlena M. Westcott PhD36.09032400000000-80.26649100000000697Westcott, MarlenaAssociate ProfessorNancyKockNancy D. Kock DVM, PhD36.09040200000000-80.26700599999999717Kock, NancyProfessor24Assistant ProfessorReeseRandleReese W. Randle MD2479Randle, ReeseAssociate ProfessorPathology, Comparative MedicineSurgery, Oncology23986580Westcott MM, Ahmed M, Smedberg JR, Rajani KR, Hiltbold EM, Lyles DSJournal of virologyWestcott MM, Ahmed M, Smedberg JR, Rajani KR, Hiltbold EM, Lyles DS. Preservation of dendritic cell function during vesicular stomatitis virus infection reflects both intrinsic and acquired mechanisms of resistance to suppression of host gene expression by viral M protein. J Virol. 2013 Nov; 87(21):11730-40.J Virol2013-08-28T00:00:002013Preservation of dendritic cell function during vesicular stomatitis virus infection reflects both intrinsic and acquired mechanisms of resistance to suppression of host gene expression by viral M protein.true1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professor21886191Stewart JH, Ahmed M, Northrup SA, Willingham M, Lyles DSCancer gene therapyStewart JH, Ahmed M, Northrup SA, Willingham M, Lyles DS. Vesicular stomatitis virus as a treatment for colorectal cancer. Cancer Gene Ther. 2011 Dec; 18(12):837-49.Cancer Gene Ther2011-09-02T00:00:002011Vesicular stomatitis virus as a treatment for colorectal cancer.20844045Ahmed M, Puckett S, Arimilli S, Braxton CL, Mizel SB, Lyles DSJournal of virologyAhmed M, Puckett S, Arimilli S, Braxton CL, Mizel SB, Lyles DS. Stimulation of human dendritic cells by wild-type and M protein mutant vesicular stomatitis viruses engineered to express bacterial flagellin. J Virol. 2010 Nov; 84(22):12093-8.J Virol2010-09-15T00:00:002010Stimulation of human dendritic cells by wild-type and M protein mutant vesicular stomatitis viruses engineered to express bacterial flagellin.23028327Rajani KR, Pettit Kneller EL, McKenzie MO, Horita DA, Chou JW, Lyles DSPLoS pathogensRajani KR, Pettit Kneller EL, McKenzie MO, Horita DA, Chou JW, Lyles DS. Complexes of vesicular stomatitis virus matrix protein with host Rae1 and Nup98 involved in inhibition of host transcription. PLoS Pathog. 2012 Sep; 8(9):e1002929.PLoS Pathog2012-09-27T00:00:002012Complexes of vesicular stomatitis virus matrix protein with host Rae1 and Nup98 involved in inhibition of host transcription.