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Targeting defective DNA repair for the prevention of BRCA1-associated cancers
Grant
Why?
Breast cancers with compromised DNA repair exhibit selective sensitivity to elesclomol.
Academic Article
Why?
DNA-repair genetic polymorphisms and breast cancer risk.
Academic Article
Why?
Loss of autophagy causes a synthetic lethal deficiency in DNA repair.
Academic Article
Why?
Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.
Academic Article
Why?
Therapeutic targeting of BRCA1-mutated breast cancers with agents that activate DNA repair.
Academic Article
Why?
Multi-scale imaging of breast cancer proteins during DNA repair
Grant
Why?
Prenatal adenovirus infection, inhibition of DNA repair, and childhood leukemia
Grant
Why?
Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling.
Academic Article
Why?
Autophagy is critically required for DNA repair by homologous recombination.
Academic Article
Why?
Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk.
Academic Article
Why?
Genetic polymorphisms of multiple DNA repair pathways impact age at diagnosis and TP53 mutations in breast cancer.
Academic Article
Why?
Proliferative activity in vitro and DNA repair indicate that adult mouse and human Sertoli cells are not terminally differentiated, quiescent cells.
Academic Article
Why?
A potential proteasome-interacting motif within the ubiquitin-like domain of parkin and other proteins.
Academic Article
Why?
Genotoxic Potential of Reactive Oxygen Species (Ros), Lipid Peroxidation and DNA Repair Enzymes (Fpg and Endo III) in Alloxan Injected Diabetic Rats.
Academic Article
Why?
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