GaganDeepGagan Deep PhD36.09032400000000-80.266491000000001924Deep, GaganProfessorprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonKounosukeWatabeKounosuke Watabe PhD36.09032400000000-80.266491000000001727Watabe, KounosukeProfessorD045744Anatomy1436590.837503Cell Line, TumorCancer BiologyDermatologyMicrobiology and ImmunologyNeurologyWake Forest School of MedicineRaviSinghRavi N. Singh PhD36.09032400000000-80.266491000000001308Singh, RaviAssistant ProfessorAnthonyAtalaAnthony Atala MD36.08943500000000-80.268632000000003Atala, AnthonyProfessorAshokHemalAshok K. Hemal MD36.08913000000000-80.2677840000000134Hemal, AshokProfessorJamesHothJames J. Hoth MD, PhD36.09032400000000-80.26649100000000425Hoth, JamesProfessorLanceMillerLance D. Miller PhD, MS36.09032400000000-80.26649100000000574Miller, LanceAssistant ProfessorMarthaAlexander-Miller4MC38pybvDqOTrPFxxARchSSnXEUZ/41PeKUY3jDi/Sa+yrfEF0=Martha A. Alexander-Miller PhD36.09032400000000-80.26649100000000603Alexander-Miller, MarthaProfessorStevenFeldmanSteven R. Feldman MD, PhD36.08959100000000-80.26859900000000884Feldman, StevenProfessorTinaBrinkleyTina E. Brinkley PhD36.08884000000000-80.27016200000000961Brinkley, TinaAssociate ProfessorYusukeShiozawaYusuke Shiozawa MD, PhD36.09032400000000-80.266491000000001731Shiozawa, YusukeAssociate ProfessorDavidSoto PantojaDavid Soto Pantoja PhD36.09032400000000-80.266491000000001771Soto Pantoja, DavidAssociate Professor8.27790.0139264362research areas0.6728360.04484687coauthor of439.43118.384150similar to1186selected publicationsAuthorship 501303Authorship 501795Authorship 502004Authorship 502061Authorship 502534Authorship 502552Authorship 502742Authorship 502901Authorship 502911Authorship 503271Authorship 503342Authorship 503363Authorship 503405Authorship 503481Authorship 503502Authorship 503611Authorship 503662Authorship 503902Authorship 504122Authorship 504203Authorship 504973Authorship 505772Authorship 506232Authorship 506242Authorship 506252Authorship 506267Authorship 506303Authorship 506361Authorship 506742Authorship 506771Authorship 506816Authorship 506821Authorship 506852Authorship 5069212Authorship 506995Authorship 5071510Authorship 507222Authorship 507276Authorship 507313Authorship 507341Authorship 508381Authorship 508765Authorship 509082Authorship 509124Authorship 509351Authorship 509562Authorship 509971Authorship 510001Authorship 510141Authorship 510252Authorship 510291Authorship 510371Authorship 510383Authorship 510951Authorship 511081Authorship 511293Authorship 511312Authorship 511393Authorship 511422Authorship 5115210Authorship 511664Authorship 511952Authorship 511973Authorship 51206116471318Deep G, Dhiman M, Rao AR, Kale RKJournal of experimental & clinical cancer research : CRDeep G, Dhiman M, Rao AR, Kale RK. Chemopreventive potential of Triphala (a composite Indian drug) on benzo(a)pyrene induced forestomach tumorigenesis in murine tumor model system. J Exp Clin Cancer Res. 2005 Dec; 24(4):555-63.J Exp Clin Cancer Res2005-12-01T00:00:002005Chemopreventive potential of Triphala (a composite Indian drug) on benzo(a)pyrene induced forestomach tumorigenesis in murine tumor model system.18006855Raina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, Pollak MN, Agarwal RCancer researchRaina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, Pollak MN, Agarwal R. Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2007 Nov 15; 67(22):11083-91.Cancer Res2007-11-15T00:00:002007Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.17916909Singh RP, Deep G, Blouin MJ, Pollak MN, Agarwal RCarcinogenesisSingh RP, Deep G, Blouin MJ, Pollak MN, Agarwal R. Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft. Carcinogenesis. 2007 Dec; 28(12):2567-74.Carcinogenesis2007-10-04T00:00:002007Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft.18701508Raina K, Rajamanickam S, Singh RP, Deep G, Chittezhath M, Agarwal RCancer researchRaina K, Rajamanickam S, Singh RP, Deep G, Chittezhath M, Agarwal R. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2008 Aug 15; 68(16):6822-30.Cancer Res2008-08-15T00:00:002008Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.16205633Deep G, Singh RP, Agarwal C, Kroll DJ, Agarwal ROncogeneDeep G, Singh RP, Agarwal C, Kroll DJ, Agarwal R. Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin. Oncogene. 2006 Feb 16; 25(7):1053-69.Oncogene2006-02-16T00:00:002006Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin.18644994Chittezhath M, Deep G, Singh RP, Agarwal C, Agarwal RMolecular cancer therapeuticsChittezhath M, Deep G, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells. . 2008 Jul; 7(7):1817-26.2008-07-01T00:00:002008Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.18516759Deep G, Agarwal RCurrent opinion in investigational drugs (London, England : 2000)Deep G, Agarwal R. New combination therapies with cell-cycle agents. Curr Opin Investig Drugs. 2008 Jun; 9(6):591-604.Curr Opin Investig Drugs2008-06-01T00:00:002008New combination therapies with cell-cycle agents.3817893Deep G, Singh MIndian journal of experimental biologyDeep G, Singh M. Modulation of cardiovascular reactivity with calcium channel blockers in rats subjected to haemorrhagic shock. Indian J Exp Biol. 1986 Aug; 24(8):524-7.Indian J Exp Biol1986-08-01T00:00:001986Modulation of cardiovascular reactivity with calcium channel blockers in rats subjected to haemorrhagic shock.15233304Deep G, Dasgupta T, Rao AR, Kale RKIndian journal of experimental biologyDeep G, Dasgupta T, Rao AR, Kale RK. Cancer preventive potential of Momordica charantia L. against benzo(a)pyrene induced fore-stomach tumourigenesis in murine model system. Indian J Exp Biol. 2004 Mar; 42(3):319-22.Indian J Exp Biol2004-03-01T00:00:002004Cancer preventive potential of Momordica charantia L. against benzo(a)pyrene induced fore-stomach tumourigenesis in murine model system.16788158Singh RP, Deep G, Chittezhath M, Kaur M, Dwyer-Nield LD, Malkinson AM, Agarwal RJournal of the National Cancer InstituteSingh RP, Deep G, Chittezhath M, Kaur M, Dwyer-Nield LD, Malkinson AM, Agarwal R. Effect of silibinin on the growth and progression of primary lung tumors in mice. J Natl Cancer Inst. 2006 Jun 21; 98(12):846-55.J Natl Cancer Inst2006-06-21T00:00:002006Effect of silibinin on the growth and progression of primary lung tumors in mice.17548792Deep G, Agarwal RIntegrative cancer therapiesDeep G, Agarwal R. Chemopreventive efficacy of silymarin in skin and prostate cancer. Integr Cancer Ther. 2007 Jun; 6(2):130-45.Integr Cancer Ther2007-06-01T00:00:002007Chemopreventive efficacy of silymarin in skin and prostate cancer.18435416Deep G, Oberlies NH, Kroll DJ, Agarwal RInternational journal of cancerDeep G, Oberlies NH, Kroll DJ, Agarwal R. Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells. Int J Cancer. 2008 Jul 01; 123(1):41-50.Int J Cancer2008-07-01T00:00:002008Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.18445658Raina K, Rajamanickam S, Deep G, Singh M, Agarwal R, Agarwal CMolecular cancer therapeuticsRaina K, Rajamanickam S, Deep G, Singh M, Agarwal R, Agarwal C. Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice. . 2008 May; 7(5):1258-67.2008-04-29T00:00:002008Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice.17389612Deep G, Oberlies NH, Kroll DJ, Agarwal RCarcinogenesisDeep G, Oberlies NH, Kroll DJ, Agarwal R. Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells. Carcinogenesis. 2007 Jul; 28(7):1533-42.Carcinogenesis2007-03-26T00:00:002007Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.18332867Deep G, Oberlies NH, Kroll DJ, Agarwal ROncogeneDeep G, Oberlies NH, Kroll DJ, Agarwal R. Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway. Oncogene. 2008 Jun 26; 27(28):3986-98.Oncogene2008-03-10T00:00:002008Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway.22126015Ravichandran K, Tyagi A, Deep G, Agarwal C, Agarwal RIndian journal of experimental biologyRavichandran K, Tyagi A, Deep G, Agarwal C, Agarwal R. Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways. Indian J Exp Biol. 2011 Nov; 49(11):840-7.Indian J Exp Biol2011-11-01T00:00:002011Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways.22166495Roy S, Deep G, Agarwal C, Agarwal RCarcinogenesisRoy S, Deep G, Agarwal C, Agarwal R. Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45a-dependent manner. Carcinogenesis. 2012 Mar; 33(3):629-36.Carcinogenesis2011-12-12T00:00:002011Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45a-dependent manner.23555889Agarwal C, Wadhwa R, Deep G, Biedermann D, Gažák R, Kren V, Agarwal RPloS oneAgarwal C, Wadhwa R, Deep G, Biedermann D, Gažák R, Kren V, Agarwal R. Anti-cancer efficacy of silybin derivatives -- a structure-activity relationship. PLoS One. 2013; 8(3):e60074.PLoS One2013-03-28T00:00:002013Anti-cancer efficacy of silybin derivatives -- a structure-activity relationship.23588585Ting H, Deep G, Agarwal RThe AAPS journalTing H, Deep G, Agarwal R. Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer. AAPS J. 2013 Jul; 15(3):707-16.AAPS J2013-04-16T00:00:002013Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer.24347249Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep GMolecular carcinogenesisRamteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Mol Carcinog. 2015 Jul; 54(7):554-65.Mol Carcinog2013-12-17T00:00:002013Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.19638451Kaur M, Velmurugan B, Tyagi A, Deep G, Katiyar S, Agarwal C, Agarwal RMolecular cancer therapeuticsKaur M, Velmurugan B, Tyagi A, Deep G, Katiyar S, Agarwal C, Agarwal R. Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft. . 2009 Aug; 8(8):2366-74.2009-07-28T00:00:002009Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft.23475945Kaur M, Deep G, Jain AK, Raina K, Agarwal C, Wempe MF, Agarwal RCarcinogenesisKaur M, Deep G, Jain AK, Raina K, Agarwal C, Wempe MF, Agarwal R. Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells. Carcinogenesis. 2013 Jul; 34(7):1585-92.Carcinogenesis2013-03-08T00:00:002013Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells.24243690Shrotriya S, Tyagi A, Deep G, Orlicky DJ, Wisell J, Wang XJ, Sclafani RA, Agarwal R, Agarwal CMolecular carcinogenesisShrotriya S, Tyagi A, Deep G, Orlicky DJ, Wisell J, Wang XJ, Sclafani RA, Agarwal R, Agarwal C. Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses. Mol Carcinog. 2015 Apr; 54(4):291-300.Mol Carcinog2013-11-14T00:00:002013Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses.18798272Deep G, Raina K, Singh RP, Oberlies NH, Kroll DJ, Agarwal RInternational journal of cancerDeep G, Raina K, Singh RP, Oberlies NH, Kroll DJ, Agarwal R. Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin. Int J Cancer. 2008 Dec 15; 123(12):2750-8.Int J Cancer2008-12-15T00:00:002008Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin.23359305Narayanapillai S, Agarwal C, Deep G, Agarwal RMolecular carcinogenesisNarayanapillai S, Agarwal C, Deep G, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 hairless mouse skin. Mol Carcinog. 2014 Jun; 53(6):471-9.Mol Carcinog2013-01-28T00:00:002013Silibinin inhibits ultraviolet B radiation-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 hairless mouse skin.24758177Bauerle KT, Schweppe RE, Lund G, Kotnis G, Deep G, Agarwal R, Pozdeyev N, Wood WM, Haugen BRThe Journal of clinical endocrinology and metabolismBauerle KT, Schweppe RE, Lund G, Kotnis G, Deep G, Agarwal R, Pozdeyev N, Wood WM, Haugen BR. Nuclear factor ?B-dependent regulation of angiogenesis, and metastasis in an in vivo model of thyroid cancer is associated with secreted interleukin-8. J Clin Endocrinol Metab. 2014 Aug; 99(8):E1436-44.J Clin Endocrinol Metab2014-04-23T00:00:002014Nuclear factor ?B-dependent regulation of angiogenesis, and metastasis in an in vivo model of thyroid cancer is associated with secreted interleukin-8.21826202Kavitha CV, Agarwal C, Agarwal R, Deep GPloS oneKavitha CV, Agarwal C, Agarwal R, Deep G. Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models. PLoS One. 2011; 6(8):e22745.PLoS One2011-08-03T00:00:002011Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models.22514647Deep G, Gangar SC, Rajamanickam S, Raina K, Gu M, Agarwal C, Oberlies NH, Agarwal RPloS oneDeep G, Gangar SC, Rajamanickam S, Raina K, Gu M, Agarwal C, Oberlies NH, Agarwal R. Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling. PLoS One. 2012; 7(4):e34630.PLoS One2012-04-13T00:00:002012Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling.22421144Sikka A, Kaur M, Agarwal C, Deep G, Agarwal RCell cycle (Georgetown, Tex.)Sikka A, Kaur M, Agarwal C, Deep G, Agarwal R. Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation. Cell Cycle. 2012 Apr 01; 11(7):1374-82.Cell Cycle2012-04-01T00:00:002012Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.23115104Kavitha CV, Deep G, Gangar SC, Jain AK, Agarwal C, Agarwal RMolecular carcinogenesisKavitha CV, Deep G, Gangar SC, Jain AK, Agarwal C, Agarwal R. Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-?B, and AP-1 activation in RAW264.7 cells. Mol Carcinog. 2014 Mar; 53(3):169-80.Mol Carcinog2012-10-31T00:00:002012Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-?B, and AP-1 activation in RAW264.7 cells.24615813Ting HJ, Deep G, Jain AK, Cimic A, Sirintrapun J, Romero LM, Cramer SD, Agarwal C, Agarwal RMolecular carcinogenesisTing HJ, Deep G, Jain AK, Cimic A, Sirintrapun J, Romero LM, Cramer SD, Agarwal C, Agarwal R. Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF ß2. Mol Carcinog. 2015 Sep; 54(9):730-41.Mol Carcinog2014-02-24T00:00:002014Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF ß2.20714788Deep G, Agarwal RCancer metastasis reviewsDeep G, Agarwal R. Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer. Cancer Metastasis Rev. 2010 Sep; 29(3):447-63.Cancer Metastasis Rev2010-09-01T00:00:002010Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer.20721970Deep G, Gangar SC, Oberlies NH, Kroll DJ, Agarwal RMolecular carcinogenesisDeep G, Gangar SC, Oberlies NH, Kroll DJ, Agarwal R. Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-?B, and androgen receptor signaling. Mol Carcinog. 2010 Oct; 49(10):902-12.Mol Carcinog2010-10-01T00:00:002010Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-?B, and androgen receptor signaling.24565133Deep G, Jain AK, Ramteke A, Ting H, Vijendra KC, Gangar SC, Agarwal C, Agarwal RMolecular cancerDeep G, Jain AK, Ramteke A, Ting H, Vijendra KC, Gangar SC, Agarwal C, Agarwal R. SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin. Mol Cancer. 2014 Feb 24; 13:37.Mol Cancer2014-02-24T00:00:002014SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin.19138987Agarwal R, Deep GCancer prevention research (Philadelphia, Pa.)Agarwal R, Deep G. Kava, a tonic for relieving the irrational development of natural preventive agents. Cancer Prev Res (Phila). 2008 Nov; 1(6):409-12.Cancer Prev Res (Phila)2008-11-01T00:00:002008Kava, a tonic for relieving the irrational development of natural preventive agents.19147767Singh RP, Raina K, Deep G, Chan D, Agarwal RClinical cancer research : an official journal of the American Association for Cancer ResearchSingh RP, Raina K, Deep G, Chan D, Agarwal R. Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling. Clin Cancer Res. 2009 Jan 15; 15(2):613-21.Clin Cancer Res2009-01-15T00:00:002009Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.20628792Velmurugan B, Gangar SC, Kaur M, Tyagi A, Deep G, Agarwal RPharmaceutical researchVelmurugan B, Gangar SC, Kaur M, Tyagi A, Deep G, Agarwal R. Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules. Pharm Res. 2010 Oct; 27(10):2085-97.Pharm Res2010-07-14T00:00:002010Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules.21546539Deep G, Gangar SC, Agarwal C, Agarwal RCancer prevention research (Philadelphia, Pa.)Deep G, Gangar SC, Agarwal C, Agarwal R. Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells. Cancer Prev Res (Phila). 2011 Aug; 4(8):1222-32.Cancer Prev Res (Phila)2011-05-05T00:00:002011Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells.22266465Shrotriya S, Deep G, Gu M, Kaur M, Jain AK, Inturi S, Agarwal R, Agarwal CCarcinogenesisShrotriya S, Deep G, Gu M, Kaur M, Jain AK, Inturi S, Agarwal R, Agarwal C. Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells. Carcinogenesis. 2012 Apr; 33(4):848-58.Carcinogenesis2012-01-19T00:00:002012Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells.23617249Deep G, Agarwal RCurrent cancer drug targetsDeep G, Agarwal R. Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy. Curr Cancer Drug Targets. 2013 Jun; 13(5):486-99.Curr Cancer Drug Targets2013-06-01T00:00:002013Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy.24389535Ting H, Deep G, Agarwal C, Agarwal RMutation researchTing H, Deep G, Agarwal C, Agarwal R. The strategies to control prostate cancer by chemoprevention approaches. Mutat Res. 2014 Feb; 760:1-15.Mutat Res2014-01-02T00:00:002014The strategies to control prostate cancer by chemoprevention approaches.26851532Rani V, Deep G, Singh RK, Palle K, Yadav UCLife sciencesRani V, Deep G, Singh RK, Palle K, Yadav UC. Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies. Life Sci. 2016 Mar 01; 148:183-93.Life Sci2016-02-03T00:00:002016Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies.25672620Somasagara RR, Deep G, Shrotriya S, Patel M, Agarwal C, Agarwal RInternational journal of oncologySomasagara RR, Deep G, Shrotriya S, Patel M, Agarwal C, Agarwal R. Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells. Int J Oncol. 2015 Apr; 46(4):1849-57.Int J Oncol2015-02-09T00:00:002015Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells.26516160Nambiar DK, Rajamani P, Deep G, Jain AK, Agarwal R, Singh RPMolecular cancer therapeuticsNambiar DK, Rajamani P, Deep G, Jain AK, Agarwal R, Singh RP. Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling. . 2015 Dec; 14(12):2722-34.2015-10-29T00:00:002015Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling.27729375Rigby CM, Roy S, Deep G, Guillermo-Lagae R, Jain AK, Dhar D, Orlicky DJ, Agarwal C, Agarwal RCarcinogenesisRigby CM, Roy S, Deep G, Guillermo-Lagae R, Jain AK, Dhar D, Orlicky DJ, Agarwal C, Agarwal R. Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis. Carcinogenesis. 2017 01; 38(1):40-50.Carcinogenesis2016-10-11T00:00:002016Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis.26447614Guillermo-Lagae R, Deep G, Ting H, Agarwal C, Agarwal ROncotargetGuillermo-Lagae R, Deep G, Ting H, Agarwal C, Agarwal R. Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts. Oncotarget. 2015 Nov 24; 6(37):39594-606.Oncotarget2015-11-24T00:00:002015Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts.25492239Tilley C, Deep G, Agarwal C, Wempe MF, Biedermann D, Valentová K, Kren V, Agarwal RMolecular carcinogenesisTilley C, Deep G, Agarwal C, Wempe MF, Biedermann D, Valentová K, Kren V, Agarwal R. Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation. Mol Carcinog. 2016 Jan; 55(1):3-14.Mol Carcinog2014-12-09T00:00:002014Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.25552257Kumar R, Deep G, Wempe MF, Agarwal R, Agarwal CCurrent cancer drug targetsKumar R, Deep G, Wempe MF, Agarwal R, Agarwal C. Procyanidin B2 3,3?-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways. Curr Cancer Drug Targets. 2015; 15(1):14-26.Curr Cancer Drug Targets2015-01-01T00:00:002015Procyanidin B2 3,3?-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways.25557495Shrotriya S, Deep G, Lopert P, Patel M, Agarwal R, Agarwal CMolecular carcinogenesisShrotriya S, Deep G, Lopert P, Patel M, Agarwal R, Agarwal C. Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells. Mol Carcinog. 2015 Dec; 54(12):1734-47.Mol Carcinog2014-12-31T00:00:002014Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.25561013Schlaepfer IR, Glodé LM, Hitz CA, Pac CT, Boyle KE, Maroni P, Deep G, Agarwal R, Lucia SM, Cramer SD, Serkova NJ, Eckel RHMolecular imaging and biologySchlaepfer IR, Glodé LM, Hitz CA, Pac CT, Boyle KE, Maroni P, Deep G, Agarwal R, Lucia SM, Cramer SD, Serkova NJ, Eckel RH. Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts. Mol Imaging Biol. 2015 Aug; 17(4):529-38.Mol Imaging Biol2015-08-01T00:00:002015Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts.26365944Kaur A, Raja HA, Deep G, Agarwal R, Oberlies NHMagnetic resonance in chemistry : MRCKaur A, Raja HA, Deep G, Agarwal R, Oberlies NH. Pannorin B, a new naphthopyrone from an endophytic fungal isolate of Penicillium sp. Magn Reson Chem. 2016 Feb; 54(2):164-7.Magn Reson Chem2015-09-14T00:00:002015Pannorin B, a new naphthopyrone from an endophytic fungal isolate of Penicillium sp.27384557Deep G, Schlaepfer IRInternational journal of molecular sciencesDeep G, Schlaepfer IR. Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis. Int J Mol Sci. 2016 Jul 02; 17(7).Int J Mol Sci2016-07-02T00:00:002016Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis.27207648Ting H, Deep G, Kumar S, Jain AK, Agarwal C, Agarwal RCarcinogenesisTing H, Deep G, Kumar S, Jain AK, Agarwal C, Agarwal R. Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment. Carcinogenesis. 2016 06; 37(6):589-599.Carcinogenesis2016-04-02T00:00:002016Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment.27279239Deep G, Panigrahi GKCritical reviews in oncogenesisDeep G, Panigrahi GK. Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor Microenvironment. Crit Rev Oncog. 2015; 20(5-6):419-34.Crit Rev Oncog2015-01-01T00:00:002015Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor Microenvironment.25284514Bailwad SA, Singh N, Jani DR, Patil P, Singh M, Deep G, Singh SOral health and dental managementBailwad SA, Singh N, Jani DR, Patil P, Singh M, Deep G, Singh S. Alterations in serum lipid profile patterns in oral cancer: correlation with histological grading and tobacco abuse. Oral Health Dent Manag. 2014 Sep; 13(3):573-9.Oral Health Dent Manag2014-09-01T00:00:002014Alterations in serum lipid profile patterns in oral cancer: correlation with histological grading and tobacco abuse.25285031Deep G, Kumar R, Jain AK, Agarwal C, Agarwal RMutation researchDeep G, Kumar R, Jain AK, Agarwal C, Agarwal R. Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling. Mutat Res. 2014 Oct; 768:35-46.Mutat Res2014-10-01T00:00:002014Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling.25294820Nambiar DK, Deep G, Singh RP, Agarwal C, Agarwal ROncotargetNambiar DK, Deep G, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1. Oncotarget. 2014 Oct 30; 5(20):10017-33.Oncotarget2014-10-30T00:00:002014Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1.26087400Schlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep GOncotargetSchlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep G. Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation. Oncotarget. 2015 Sep 08; 6(26):22836-56.Oncotarget2015-09-08T00:00:002015Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation.27048854Kaur A, Raja HA, Swenson DC, Agarwal R, Deep G, Falkinham JO, Oberlies NHPhytochemistryKaur A, Raja HA, Swenson DC, Agarwal R, Deep G, Falkinham JO, Oberlies NH. Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus. Phytochemistry. 2016 Jun; 126:4-10.Phytochemistry2016-04-02T00:00:002016Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus.25252179Kavitha CV, Jain AK, Agarwal C, Pierce A, Keating A, Huber KM, Serkova NJ, Wempe MF, Agarwal R, Deep GMolecular carcinogenesisKavitha CV, Jain AK, Agarwal C, Pierce A, Keating A, Huber KM, Serkova NJ, Wempe MF, Agarwal R, Deep G. Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo. Mol Carcinog. 2015 Nov; 54(11):1417-29.Mol Carcinog2014-09-22T00:00:002014Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.26053157Tilley C, Deep G, Agarwal RMolecular carcinogenesisTilley C, Deep G, Agarwal R. Chemopreventive opportunities to control basal cell carcinoma: Current perspectives. Mol Carcinog. 2015 Sep; 54(9):688-97.Mol Carcinog2015-06-05T00:00:002015Chemopreventive opportunities to control basal cell carcinoma: Current perspectives.26894057Khadse SV, Bajaj G, Vibhakar P, Nainani P, Ahuja R, Deep GJournal of clinical and diagnostic research : JCDRKhadse SV, Bajaj G, Vibhakar P, Nainani P, Ahuja R, Deep G. Evaluation of Specificity and Sensitivity of Oral Fluid for Diagnosis of Hepatitis B. J Clin Diagn Res. 2016 Jan; 10(1):BC12-4.J Clin Diagn Res2016-01-01T00:00:002016Evaluation of Specificity and Sensitivity of Oral Fluid for Diagnosis of Hepatitis B.26949450Yadav UC, Rani V, Deep G, Singh RK, Palle KOxidative medicine and cellular longevityYadav UC, Rani V, Deep G, Singh RK, Palle K. Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics. Oxid Med Cell Longev. 2016; 2016:9137629.Oxid Med Cell Longev2016-02-01T00:00:002016Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics.26979487Deep G, Kumar R, Jain AK, Dhar D, Panigrahi GK, Hussain A, Agarwal C, El-Elimat T, Sica VP, Oberlies NH, Agarwal RScientific reportsDeep G, Kumar R, Jain AK, Dhar D, Panigrahi GK, Hussain A, Agarwal C, El-Elimat T, Sica VP, Oberlies NH, Agarwal R. Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity. Sci Rep. 2016 Mar 16; 6:23135.Sci Rep2016-03-16T00:00:002016Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity.Authorship 52533226097804Kumar R, Deep G, Agarwal RCurrent pharmacology reportsKumar R, Deep G, Agarwal R. An Overview of Ultraviolet B Radiation-Induced Skin Cancer Chemoprevention by Silibinin. Curr Pharmacol Rep. 2015 Jun 01; 1(3):206-215.Curr Pharmacol Rep2015-06-01T00:00:002015An Overview of Ultraviolet B Radiation-Induced Skin Cancer Chemoprevention by Silibinin.Authorship 528066Authorship 529361Authorship 53056626000195Raja HA, Kaur A, El-Elimat T, Figueroa M, Kumar R, Deep G, Agarwal R, Faeth SH, Cech NB, Oberlies NHMycologyRaja HA, Kaur A, El-Elimat T, Figueroa M, Kumar R, Deep G, Agarwal R, Faeth SH, Cech NB, Oberlies NH. Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle). Mycology. 2015 Jan 02; 6(1):8-27.Mycology2015-01-02T00:00:002015Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle).27533043Deep G, Kumar R, Nambiar DK, Jain AK, Ramteke AM, Serkova NJ, Agarwal C, Agarwal RMolecular carcinogenesisDeep G, Kumar R, Nambiar DK, Jain AK, Ramteke AM, Serkova NJ, Agarwal C, Agarwal R. Silibinin inhibits hypoxia-induced HIF-1a-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics. Mol Carcinog. 2017 03; 56(3):833-848.Mol Carcinog2016-09-05T00:00:002016Silibinin inhibits hypoxia-induced HIF-1a-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics.28120452Dheeraj A, Rigby CM, O'Bryant CL, Agarwal C, Singh RP, Deep G, Agarwal RPhotochemistry and photobiologyDheeraj A, Rigby CM, O'Bryant CL, Agarwal C, Singh RP, Deep G, Agarwal R. Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor-Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling. Photochem Photobiol. 2017 07; 93(4):999-1007.Photochem Photobiol2017-03-06T00:00:002017Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor-Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling.Authorship 53669228410139Panigrahi GK, Deep GFrontiers in bioscience (Landmark edition)Panigrahi GK, Deep G. Exosomes-based biomarker discovery for diagnosis and prognosis of prostate cancer. Front Biosci (Landmark Ed). 2017 06 01; 22:1682-1696.Front Biosci (Landmark Ed)2017-06-01T00:00:002017Exosomes-based biomarker discovery for diagnosis and prognosis of prostate cancer.Authorship 55506228876465Kumar R, Deep G, Wempe MF, Surek J, Kumar A, Agarwal R, Agarwal CMolecular carcinogenesisKumar R, Deep G, Wempe MF, Surek J, Kumar A, Agarwal R, Agarwal C. Procyanidin B2 3,3?-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK. Mol Carcinog. 2018 Jan; 57(1):57-69.Mol Carcinog2017-09-22T00:00:002017Procyanidin B2 3,3?-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK.CarynMorseCaryn G. Morse MD, MPH36.09032400000000-80.266491000000002104Morse, CarynAssistant ProfessorAuthorship 578492Authorship 580248Authorship 5820411Authorship 587392Authorship 5935912Authorship 594798Authorship 595525Authorship 59700730016827Rivera-Chávez J, El-Elimat T, Gallagher JM, Graf TN, Fournier J, Panigrahi GK, Deep G, Bunch RL, Raja HA, Oberlies NHPlanta medicaRivera-Chávez J, El-Elimat T, Gallagher JM, Graf TN, Fournier J, Panigrahi GK, Deep G, Bunch RL, Raja HA, Oberlies NH. Delitpyrones: a-Pyrone Derivatives from a Freshwater Delitschia sp. Planta Med. 2019 Jan; 85(1):62-71.Planta Med2018-07-17T00:00:002018Delitpyrones: a-Pyrone Derivatives from a Freshwater Delitschia sp.29727019Dhar D, Deep G, Kumar S, Wempe MF, Raina K, Agarwal C, Agarwal RMolecular carcinogenesisDhar D, Deep G, Kumar S, Wempe MF, Raina K, Agarwal C, Agarwal R. Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells. Mol Carcinog. 2018 09; 57(9):1166-1180.Mol Carcinog2018-05-18T00:00:002018Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells.29497081Panigrahi GK, Praharaj PP, Peak TC, Long J, Singh R, Rhim JS, Abd Elmageed ZY, Deep GScientific reportsPanigrahi GK, Praharaj PP, Peak TC, Long J, Singh R, Rhim JS, Abd Elmageed ZY, Deep G. Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells. Sci Rep. 2018 03 01; 8(1):3853.Sci Rep2018-03-01T00:00:002018Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells.29360544Praharaj PP, Bhutia SK, Nagrath S, Bitting RL, Deep GBiochimica et biophysica acta. Reviews on cancerPraharaj PP, Bhutia SK, Nagrath S, Bitting RL, Deep G. Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine. Biochim Biophys Acta Rev Cancer. 2018 Apr; 1869(2):117-127.Biochim Biophys Acta Rev Cancer2018-01-31T00:00:002018Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine.29627574Peak TC, Praharaj PP, Panigrahi GK, Doyle M, Su Y, Schlaepfer IR, Singh R, Vander Griend DJ, Alickson J, Hemal A, Atala A, Deep GBiochemical and biophysical research communicationsPeak TC, Praharaj PP, Panigrahi GK, Doyle M, Su Y, Schlaepfer IR, Singh R, Vander Griend DJ, Alickson J, Hemal A, Atala A, Deep G. Exosomes secreted by placental stem cells selectively inhibit growth of aggressive prostate cancer cells. Biochem Biophys Res Commun. 2018 05 23; 499(4):1004-1010.Biochem Biophys Res Commun2018-04-09T00:00:002018Exosomes secreted by placental stem cells selectively inhibit growth of aggressive prostate cancer cells.29691455Panigrahi GK, Praharaj PP, Peak TC, Long J, Singh R, Rhim JS, Abd Elmageed ZY, Deep GScientific reportsPanigrahi GK, Praharaj PP, Peak TC, Long J, Singh R, Rhim JS, Abd Elmageed ZY, Deep G. Author Correction: Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells. Sci Rep. 2018 Apr 24; 8(1):6645.Sci Rep2018-04-24T00:00:002018Author Correction: Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells.29702093Patterson SA, Deep G, Brinkley TEBiochemical and biophysical research communicationsPatterson SA, Deep G, Brinkley TE. Detection of the receptor for advanced glycation endproducts in neuronally-derived exosomes in plasma. Biochem Biophys Res Commun. 2018 06 12; 500(4):892-896.Biochem Biophys Res Commun2018-04-30T00:00:002018Detection of the receptor for advanced glycation endproducts in neuronally-derived exosomes in plasma.29568403Panigrahi GK, Ramteke A, Birks D, Abouzeid Ali HE, Venkataraman S, Agarwal C, Vibhakar R, Miller LD, Agarwal R, Abd Elmageed ZY, Deep GOncotargetPanigrahi GK, Ramteke A, Birks D, Abouzeid Ali HE, Venkataraman S, Agarwal C, Vibhakar R, Miller LD, Agarwal R, Abd Elmageed ZY, Deep G. Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer. Oncotarget. 2018 Mar 02; 9(17):13894-13910.Oncotarget2018-02-17T00:00:002018Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer.2018-06-30NIHDEEP, GAGAN2015-07-15Exosomes Promote Disease Aggressiveness in African American Prostate CancerR21CA199628Principal Investigator2023-04-30NIHMOLINA, ANTHONY J2018-09-30Exosome Mediated Alterations in Cellular Metabolism in the Pathogenesis and Progression of Alzheimer's DiseaseR01AG061805Co-Principal Investigator30474051Ahmadi S, Mainali R, Nagpal R, Sheikh-Zeinoddin M, Soleimanian-Zad S, Wang S, Deep G, Kumar Mishra S, Yadav HObesity & control therapies : open accessAhmadi S, Mainali R, Nagpal R, Sheikh-Zeinoddin M, Soleimanian-Zad S, Wang S, Deep G, Kumar Mishra S, Yadav H. Dietary Polysaccharides in the Amelioration of Gut Microbiome Dysbiosis and Metabolic Diseases. Obes Control Ther. 2017; 4(3).Obes Control Ther2017-12-18T00:00:002017Dietary Polysaccharides in the Amelioration of Gut Microbiome Dysbiosis and Metabolic Diseases.30623593Panigrahi GK, Praharaj PP, Kittaka H, Mridha AR, Black OM, Singh R, Mercer R, van Bokhoven A, Torkko KC, Agarwal C, Agarwal R, Abd Elmageed ZY, Yadav H, Mishra SK, Deep GCancer medicinePanigrahi GK, Praharaj PP, Kittaka H, Mridha AR, Black OM, Singh R, Mercer R, van Bokhoven A, Torkko KC, Agarwal C, Agarwal R, Abd Elmageed ZY, Yadav H, Mishra SK, Deep G. Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients. Cancer Med. 2019 03; 8(3):1110-1123.Cancer Med2019-01-08T00:00:002019Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients.31101996Solingapuram Sai KK, Bashetti N, Chen X, Norman S, Hines JW, Meka O, Kumar JVS, Devanathan S, Deep G, Furdui CM, Mintz AEJNMMI researchSolingapuram Sai KK, Bashetti N, Chen X, Norman S, Hines JW, Meka O, Kumar JVS, Devanathan S, Deep G, Furdui CM, Mintz A. Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer. EJNMMI Res. 2019 May 17; 9(1):43.EJNMMI Res2019-05-17T00:00:002019Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer.2024-04-30NIHDEEP, GAGAN2019-07-01Neuronal exosomes in cocaine abuse and treatment response in socially housed monkeysR01DA049267Principal Investigator20ProfessorAuthorship 640447Authorship 645945Authorship 646528Authorship 646816Authorship 652297Authorship 661812Authorship 6652015Authorship 67124930397274Ali HEA, Lung PY, Sholl AB, Gad SA, Bustamante JJ, Ali HI, Rhim JS, Deep G, Zhang J, Abd Elmageed ZYScientific reportsAli HEA, Lung PY, Sholl AB, Gad SA, Bustamante JJ, Ali HI, Rhim JS, Deep G, Zhang J, Abd Elmageed ZY. Dysregulated gene expression predicts tumor aggressiveness in African-American prostate cancer patients. Sci Rep. 2018 11 05; 8(1):16335.Sci Rep2018-11-05T00:00:002018Dysregulated gene expression predicts tumor aggressiveness in African-American prostate cancer patients.30816681Peak TC, Su Y, Chapple AG, Chyr J, Deep GScientific reportsPeak TC, Su Y, Chapple AG, Chyr J, Deep G. Syntaxin 6: A novel predictive and prognostic biomarker in papillary renal cell carcinoma. Sci Rep. 2019 02 28; 9(1):3146.Sci Rep2019-02-28T00:00:002019Syntaxin 6: A novel predictive and prognostic biomarker in papillary renal cell carcinoma.30912211Rigby C, Deep G, Jain A, Orlicky DJ, Agarwal C, Agarwal RMolecular carcinogenesisRigby C, Deep G, Jain A, Orlicky DJ, Agarwal C, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma. Mol Carcinog. 2019 07; 58(7):1260-1271.Mol Carcinog2019-03-25T00:00:002019Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma.30409162Niture S, Gyamfi MA, Kedir H, Arthur E, Ressom H, Deep G, Kumar DCell communication and signaling : CCSNiture S, Gyamfi MA, Kedir H, Arthur E, Ressom H, Deep G, Kumar D. Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway. Cell Commun Signal. 2018 11 08; 16(1):78.Cell Commun Signal2018-11-08T00:00:002018Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway.30175155Dheeraj A, Agarwal C, Schlaepfer IR, Raben D, Singh R, Agarwal R, Deep GHypoxia (Auckland, N.Z.)Dheeraj A, Agarwal C, Schlaepfer IR, Raben D, Singh R, Agarwal R, Deep G. A novel approach to target hypoxic cancer cells via combining ß-oxidation inhibitor etomoxir with radiation. Hypoxia (Auckl). 2018; 6:23-33.Hypoxia (Auckl)2018-08-21T00:00:002018A novel approach to target hypoxic cancer cells via combining ß-oxidation inhibitor etomoxir with radiation.24Assistant Professor22Associate ProfessorInternal Medicine, Gerontology & Geriatric MedicineInternal Medicine, Hematology & OncologyObstetrics and Gynecology, Maternal FetalSurgery, HypertensionSurgery, TraumaUrologyWake Forest Institute for Regenerative Medicinehttp://www.wfirm.orgWFIRMtrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessor2ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor3ProfessorProfessorKiran KumarSolingapuram SaixtKq6p2U9RqiXKrPzBwRYVWrnDMdZvk=Kiran Kumar Solingapuram Sai PhD36.08808900000000-80.268484000000001587Solingapuram Sai, Kiran KumarAssociate ProfessorDiagnostic RadiologyD055354Anatomy22370.944001ExosomesD012838Chemicals & Drugs2380.964653SilymarinD015398Physiology1676070.76081Signal TransductionD011471Disorders834380.69851Prostatic Neoplasms