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Rodolfo M. Pascual MD

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentInternal Medicine, Pulmonary, Critical Care, Allergy and Immunologic Diseases
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cornelison SD, Pascual RM. Pulmonary Rehabilitation in the Management of Chronic Lung Disease. Med Clin North Am. 2019 May; 103(3):577-584. PMID: 30955523.
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    2. Justice JN, Nambiar AM, Tchkonia T, LeBrasseur NK, Pascual R, Hashmi SK, Prata L, Masternak MM, Kritchevsky SB, Musi N, Kirkland JL. Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. EBioMedicine. 2019 Feb; 40:554-563. PMID: 30616998.
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    3. Bellinger C, Bleecker ER, Peters S, Pascual R, Krings J, Smith R, Hastie AT, Moore WC. Effects of bronchoscopy on lung function in asthmatics. J Asthma. 2017 Oct; 54(8):866-871. PMID: 28055281.
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    4. Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1068-1074.e1. PMID: 24084072.
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    5. Hastie AT, Moore WC, Li H, Rector BM, Ortega VE, Pascual RM, Peters SP, Meyers DA, Bleecker ER. Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. J Allergy Clin Immunol. 2013 Jul; 132(1):72-80. PMID: 23706399.
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    6. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97. PMID: 22968888.
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    7. Pascual RM, Peters SP. Asthma. Med Clin North Am. 2011 Nov; 95(6):1115-24. PMID: 22032430.
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    8. Moore WC, Evans MD, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Curran-Everett D, Dweik RA, Gaston B, Hew M, Israel E, Mayse ML, Pascual RM, Peters SP, Silveira L, Wenzel SE, Jarjour NN. Safety of investigative bronchoscopy in the Severe Asthma Research Program. J Allergy Clin Immunol. 2011 Aug; 128(2):328-336.e3. PMID: 21496892.
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    9. Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010 Oct 28; 363(18):1715-26. PMID: 20979471.
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    10. Yan H, Deshpande DA, Misior AM, Miles MC, Saxena H, Riemer EC, Pascual RM, Panettieri RA, Penn RB. Anti-mitogenic effects of ß-agonists and PGE2 on airway smooth muscle are PKA dependent. FASEB J. 2011 Jan; 25(1):389-97. PMID: 20805374.
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    11. Moore WC, Pascual RM. Update in asthma 2009. Am J Respir Crit Care Med. 2010 Jun 01; 181(11):1181-7. PMID: 20516492.
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    12. Pascual RM, Bleecker ER. Pharmacogenetics of asthma. Curr Opin Pharmacol. 2010 Jun; 10(3):226-35. PMID: 20646961.
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    13. Pascual RM, Peters SP. The irreversible component of persistent asthma. J Allergy Clin Immunol. 2009 Nov; 124(5):883-90; quiz 891-2. PMID: 19895980.
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    14. Misior AM, Deshpande DA, Loza MJ, Pascual RM, Hipp JD, Penn RB. Glucocorticoid- and protein kinase A-dependent transcriptome regulation in airway smooth muscle. Am J Respir Cell Mol Biol. 2009 Jul; 41(1):24-39. PMID: 19059887.
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    15. Kong KC, Gandhi U, Martin TJ, Anz CB, Yan H, Misior AM, Pascual RM, Deshpande DA, Penn RB. Endogenous Gs-coupled receptors in smooth muscle exhibit differential susceptibility to GRK2/3-mediated desensitization. Biochemistry. 2008 Sep 02; 47(35):9279-88. PMID: 18690720.
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    16. Misior AM, Yan H, Pascual RM, Deshpande DA, Panettieri RA, Penn RB. Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors. Mol Pharmacol. 2008 Feb; 73(2):566-74. PMID: 17993511.
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    17. Deshpande DA, Pascual RM, Wang SW, Eckman DM, Riemer EC, Funk CD, Penn RB. PKC-dependent regulation of the receptor locus dominates functional consequences of cysteinyl leukotriene type 1 receptor activation. FASEB J. 2007 Aug; 21(10):2335-42. PMID: 17392478.
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    18. Pascual RM, Carr EM, Seeds MC, Guo M, Panettieri RA, Peters SP, Penn RB. Regulatory features of interleukin-1beta-mediated prostaglandin E2 synthesis in airway smooth muscle. . 2006 Mar; 290(3):L501-8. PMID: 16299051.
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    19. Guo M, Pascual RM, Wang S, Fontana MF, Valancius CA, Panettieri RA, Tilley SL, Penn RB. Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms. Biochemistry. 2005 Oct 25; 44(42):13771-82. PMID: 16229467.
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    20. Pascual RM, Peters SP. Airway remodeling contributes to the progressive loss of lung function in asthma: an overview. J Allergy Clin Immunol. 2005 Sep; 116(3):477-86; quiz 487. PMID: 16159612.
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    21. Urbano FL, Pascual RM. Contemporary issues in the care of patients with chronic obstructive pulmonary disease. J Manag Care Pharm. 2005 Jun; 11(5 Suppl A):S2-13; quiz S14-6. PMID: 15934804.
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    22. Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, Kohout TA, Eckman DM, Benovic JL, Penn RB. Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. J Biol Chem. 2005 Mar 11; 280(10):8722-32. PMID: 15590629.
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    23. Robertson NM, Zangrilli JG, Steplewski A, Hastie A, Lindemeyer RG, Planeta MA, Smith MK, Innocent N, Musani A, Pascual R, Peters S, Litwack G. Differential expression of TRAIL and TRAIL receptors in allergic asthmatics following segmental antigen challenge: evidence for a role of TRAIL in eosinophil survival. J Immunol. 2002 Nov 15; 169(10):5986-96. PMID: 12421985.
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