ChristopherPoradaChristopher Porada PhD36.08943500000000-80.26863200000000164Porada, ChristopherProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 389071Authorship 396925Authorship 4064310Authorship 41110124316783Porada CD, Stem C, Almeida-Porada GNorth Carolina medical journalPorada CD, Stem C, Almeida-Porada G. Gene therapy: the promise of a permanent cure. N C Med J. 2013 Nov-Dec; 74(6):526-9.N C Med J2013-11-01T00:00:002013Gene therapy: the promise of a permanent cure.24673111Jeanblanc C, Goodrich AD, Colletti E, Mokhtari S, Porada CD, Zanjani ED, Almeida-Porada GBritish journal of haematologyJeanblanc C, Goodrich AD, Colletti E, Mokhtari S, Porada CD, Zanjani ED, Almeida-Porada G. Temporal definition of haematopoietic stem cell niches in a large animal model of in utero stem cell transplantation. Br J Haematol. 2014 Jul; 166(2):268-78.Br J Haematol2014-03-27T00:00:002014Temporal definition of haematopoietic stem cell niches in a large animal model of in utero stem cell transplantation.25186828Shaw SW, Blundell MP, Pipino C, Shangaris P, Maghsoudlou P, Ramachandra DL, Georgiades F, Boyd M, Thrasher AJ, Porada CD, Almeida-Porada G, Cheng PJ, David AL, de Coppi PStem cells (Dayton, Ohio)Shaw SW, Blundell MP, Pipino C, Shangaris P, Maghsoudlou P, Ramachandra DL, Georgiades F, Boyd M, Thrasher AJ, Porada CD, Almeida-Porada G, Cheng PJ, David AL, de Coppi P. Sheep CD34+ amniotic fluid cells have hematopoietic potential and engraft after autologous in utero transplantation. Stem Cells. 2015 Jan; 33(1):122-32.Stem Cells2015-01-01T00:00:002015Sheep CD34+ amniotic fluid cells have hematopoietic potential and engraft after autologous in utero transplantation.25566073Porada CD, Rodman C, Ignacio G, Atala A, Almeida-Porada GFrontiers in pharmacologyPorada CD, Rodman C, Ignacio G, Atala A, Almeida-Porada G. Hemophilia A: an ideal disease to correct in utero. Front Pharmacol. 2014; 5:276.Front Pharmacol2014-12-11T00:00:002014Hemophilia A: an ideal disease to correct in utero.Wake Forest School of MedicineFrankMariniFrank C. Marini PhD36.08943500000000-80.268632000000001107Marini, FrankProfessorColinBishopColin E. Bishop PhD36.08943500000000-80.26863200000000122Bishop, ColinProfessorCarlLangefeldCarl D. Langefeld PhD36.09550200000000-80.24393700000000149Langefeld, CarlProfessor2.491170.00873032254research areas8.910720.04119166coauthor of106.6824.8659350similar to1153selected publicationsM GracaAlmeida-PoradaM Graca N. Almeida-Porada MD, PhD36.08943500000000-80.26863200000000297Almeida-Porada, M GracaProfessorAnthonyAtalaAnthony Atala MD36.08943500000000-80.268632000000003Atala, AnthonyProfessorJamesYooJames J. Yoo MD, PhD36.08943500000000-80.26863200000000500Yoo, JamesProfessorShaySokerShay Soker PhD36.08943500000000-80.26863200000000939Soker, ShayProfessorStephenWalkerStephen J. Walker PhD36.08943500000000-80.26863200000000950Walker, StephenProfessorThomasShupeThomas D. Shupe PhD36.08943500000000-80.26863200000000995Shupe, ThomasAssociate ProfessorYoung MinJuYoung Min Ju PhD36.08943500000000-80.268632000000001787Ju, Young MinAssistant ProfessorAuthorship 43076426042793Ross CL, Siriwardane M, Almeida-Porada G, Porada CD, Brink P, Christ GJ, Harrison BSStem cell researchRoss CL, Siriwardane M, Almeida-Porada G, Porada CD, Brink P, Christ GJ, Harrison BS. The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation. Stem Cell Res. 2015 Jul; 15(1):96-108.Stem Cell Res2015-05-12T00:00:002015The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation.Authorship 47027526528440Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DAFrontiers in oncologyMuralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA. Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers. Front Oncol. 2015; 5:231.Front Oncol2015-10-14T00:00:002015Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.Authorship 47355526636037Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DAFrontiers in oncologyMuralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA. Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers. Front Oncol. 2015; 5:255.Front Oncol2015-11-25T00:00:002015Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.Authorship 487851Authorship 48809326319943Porada CD, Atala AJ, Almeida-Porada GMethods (San Diego, Calif.)Porada CD, Atala AJ, Almeida-Porada G. The hematopoietic system in the context of regenerative medicine. Methods. 2016 Apr 15; 99:44-61.Methods2015-08-28T00:00:002015The hematopoietic system in the context of regenerative medicine.27069953Almeida-Porada G, Atala A, Porada CDMolecular therapy. Methods & clinical developmentAlmeida-Porada G, Atala A, Porada CD. In utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical application. Mol Ther Methods Clin Dev. 2016; 5:16020.Mol Ther Methods Clin Dev2016-03-30T00:00:002016In utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical application.Authorship 49278527304918Mokhtari S, Colletti EJ, Atala A, Zanjani ED, Porada CD, Almeida-Porada GStem cell reportsMokhtari S, Colletti EJ, Atala A, Zanjani ED, Porada CD, Almeida-Porada G. Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation. Stem Cell Reports. 2016 06 14; 6(6):957-969.Stem Cell Reports2016-06-14T00:00:002016Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation.Authorship 515201Authorship 51637623264887Porada CD, Almeida-Porada GJournal of genetic syndromes & gene therapyPorada CD, Almeida-Porada G. Treatment of Hemophilia A in Utero and Postnatally using Sheep as a Model for Cell and Gene Delivery. J Genet Syndr Gene Ther. 2012 May 25; S1.J Genet Syndr Gene Ther2012-05-25T00:00:002012Treatment of Hemophilia A in Utero and Postnatally using Sheep as a Model for Cell and Gene Delivery.25279386Boura JS, Vance M, Yin W, Madeira C, Lobato da Silva C, Porada CD, Almeida-Porada GMolecular therapy. Methods & clinical developmentBoura JS, Vance M, Yin W, Madeira C, Lobato da Silva C, Porada CD, Almeida-Porada G. Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells. Mol Ther Methods Clin Dev. 2014 Sep; 2014(1).Mol Ther Methods Clin Dev2014-09-01T00:00:002014Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells.2008-02-28NIHPORADA, CHRISTOPHER D2002-03-01In Utero Gene TherapyR01HD0430382021-05-31NIHALMEIDA-PORADA, GRACA DUARTE2016-09-01Postnatal Cell-Based Therapies for Hemophilia AR01HL130856Principal InvestigatorCo-Principal Investigator2021-06-30NIHALMEIDA-PORADA, GRACA DUARTE2017-07-14Prenatal Cell and Gene Therapy for Hemophilia AR01HL135853Co-Principal InvestigatorAuthorship 35114423998755Almeida-Porada G, Soland M, Boura J, Porada CDRegenerative medicineAlmeida-Porada G, Soland M, Boura J, Porada CD. Regenerative medicine: prospects for the treatment of inflammatory bowel disease. Regen Med. 2013 Sep; 8(5):631-44.Regen Med2013-09-01T00:00:002013Regenerative medicine: prospects for the treatment of inflammatory bowel disease.29891936Mokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons PJ, Walker S, Bishop C, Atala A, Zanjani ED, Porada CD, Almeida-Porada GLeukemiaMokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons PJ, Walker S, Bishop C, Atala A, Zanjani ED, Porada CD, Almeida-Porada G. Correction: A human bone marrow mesodermal-derived cell population with hemogenic potential. Leukemia. 2018 07; 32(7):1670.Leukemia2018-07-01T00:00:002018Correction: A human bone marrow mesodermal-derived cell population with hemogenic potential.29467489Mokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons PJ, Walker S, Bishop C, Atala A, Zanjani ED, Porada CD, Almeida-Porada GLeukemiaMokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons PJ, Walker S, Bishop C, Atala A, Zanjani ED, Porada CD, Almeida-Porada G. A human bone marrow mesodermal-derived cell population with hemogenic potential. Leukemia. 2018 07; 32(7):1575-1586.Leukemia2018-02-02T00:00:002018A human bone marrow mesodermal-derived cell population with hemogenic potential.Authorship 583609Authorship 586626Authorship 5949512Authorship 6063811Authorship 606411129901426Low EK, Brudvik E, Kuhlman B, Wilson PF, Almeida-Porada G, Porada CDStem cells and developmentLow EK, Brudvik E, Kuhlman B, Wilson PF, Almeida-Porada G, Porada CD. Microgravity Impairs DNA Damage Repair in Human Hematopoietic Stem/Progenitor Cells and Inhibits Their Differentiation into Dendritic Cells. Stem Cells Dev. 2018 09 15; 27(18):1257-1267.Stem Cells Dev2018-07-16T00:00:002018Microgravity Impairs DNA Damage Repair in Human Hematopoietic Stem/Progenitor Cells and Inhibits Their Differentiation into Dendritic Cells.29698131Almeida-Porada G, Rodman C, Kuhlman B, Brudvik E, Moon J, George S, Guida P, Sajuthi SP, Langefeld CD, Walker SJ, Wilson PF, Porada CDStem cells and developmentAlmeida-Porada G, Rodman C, Kuhlman B, Brudvik E, Moon J, George S, Guida P, Sajuthi SP, Langefeld CD, Walker SJ, Wilson PF, Porada CD. Exposure of the Bone Marrow Microenvironment to Simulated Solar and Galactic Cosmic Radiation Induces Biological Bystander Effects on Human Hematopoiesis. Stem Cells Dev. 2018 09 15; 27(18):1237-1256.Stem Cells Dev2018-04-26T00:00:002018Exposure of the Bone Marrow Microenvironment to Simulated Solar and Galactic Cosmic Radiation Induces Biological Bystander Effects on Human Hematopoiesis.29473346Mokhtari S, Baptista PM, Vyas DA, Freeman CJ, Moran E, Brovold M, Llamazares GA, Lamar Z, Porada CD, Soker S, Almeida-Porada GStem cells translational medicineMokhtari S, Baptista PM, Vyas DA, Freeman CJ, Moran E, Brovold M, Llamazares GA, Lamar Z, Porada CD, Soker S, Almeida-Porada G. Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments. Stem Cells Transl Med. 2018 03; 7(3):271-282.Stem Cells Transl Med2018-02-23T00:00:002018Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments.2021-06-30NIHALMEIDA-PORADA, GRACA DUARTE2019-07-01cGMP Manufacture Of FVIII-Expressing Placental Cells For Hemophilia AU01HL148681Co-Principal InvestigatorAuthorship 65048630837116Almeida-Porada G, Waddington SN, Chan JKY, Peranteau WH, MacKenzie T, Porada CDMolecular therapy : the journal of the American Society of Gene TherapyAlmeida-Porada G, Waddington SN, Chan JKY, Peranteau WH, MacKenzie T, Porada CD. In Utero Gene Therapy Consensus Statement from the IFeTIS. Mol Ther. 2019 04 10; 27(4):705-707.Mol Ther2019-03-02T00:00:002019In Utero Gene Therapy Consensus Statement from the IFeTIS.24Assistant ProfessorDepartment of PA StudiesPHS-Biostatistics and Data Science (Public Health Sciences)UrologyWake Forest Institute for Regenerative Medicinehttp://www.wfirm.orgWFIRMAuthorship 116858Authorship 118681Authorship 35972924086458Tellez J, Van Vliet K, Tseng YS, Finn JD, Tschernia N, Almeida-Porada G, Arruda VR, Agbandje-McKenna M, Porada CDPloS oneTellez J, Van Vliet K, Tseng YS, Finn JD, Tschernia N, Almeida-Porada G, Arruda VR, Agbandje-McKenna M, Porada CD. Characterization of naturally-occurring humoral immunity to AAV in sheep. PLoS One. 2013; 8(9):e75142.PLoS One2013-09-24T00:00:002013Characterization of naturally-occurring humoral immunity to AAV in sheep.Authorship 12613Authorship 137121Authorship 139609Authorship 142146Authorship 142433Authorship 147952Authorship 157553Authorship 178042Authorship 181041Authorship 1836812ProfessorProfessor3Clinical Adjunct FacultyClinical Adjunct Facultytrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 186397Authorship 204972Authorship 206071Authorship 220532Authorship 225235Authorship 225354Authorship 26404Authorship 267453Authorship 300755Authorship 323802Authorship 328176Authorship 333471Authorship 341501Authorship 36379Authorship 51404Authorship 55044Authorship 84526Authorship 92461Authorship 9362Authorship 9428711975852Porada CD, Tran ND, Almeida-Porada G, Glimp HA, Pixley JS, Zhao Y, Anderson WF, Zanjani EDHuman gene therapyPorada CD, Tran ND, Almeida-Porada G, Glimp HA, Pixley JS, Zhao Y, Anderson WF, Zanjani ED. Transduction of long-term-engrafting human hematopoietic stem cells by retroviral vectors. Hum Gene Ther. 2002 May 01; 13(7):867-79.Hum Gene Ther2002-05-01T00:00:002002Transduction of long-term-engrafting human hematopoietic stem cells by retroviral vectors.14646413Porada CD, Park P, Almeida-Porada G, Zanjani EDFetal diagnosis and therapyPorada CD, Park P, Almeida-Porada G, Zanjani ED. The sheep model of in utero gene therapy. Fetal Diagn Ther. 2004 Jan-Feb; 19(1):23-30.Fetal Diagn Ther2004-01-01T00:00:002004The sheep model of in utero gene therapy.15774617Lucas ML, Seidel NE, Porada CD, Quigley JG, Anderson SM, Malech HL, Abkowitz JL, Zanjani ED, Bodine DMBloodLucas ML, Seidel NE, Porada CD, Quigley JG, Anderson SM, Malech HL, Abkowitz JL, Zanjani ED, Bodine DM. Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes. Blood. 2005 Jul 01; 106(1):51-8.Blood2005-03-17T00:00:002005Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes.17889724Almeida-Porada G, Porada C, Gupta N, Torabi A, Thain D, Zanjani EDExperimental hematologyAlmeida-Porada G, Porada C, Gupta N, Torabi A, Thain D, Zanjani ED. The human-sheep chimeras as a model for human stem cell mobilization and evaluation of hematopoietic grafts' potential. Exp Hematol. 2007 Oct; 35(10):1594-600.Exp Hematol2007-10-01T00:00:002007The human-sheep chimeras as a model for human stem cell mobilization and evaluation of hematopoietic grafts' potential.18155552Frias AM, Porada CD, Crapnell KB, Cabral JM, Zanjani ED, Almeida-Porada GExperimental hematologyFrias AM, Porada CD, Crapnell KB, Cabral JM, Zanjani ED, Almeida-Porada G. Generation of functional natural killer and dendritic cells in a human stromal-based serum-free culture system designed for cord blood expansion. Exp Hematol. 2008 Jan; 36(1):61-8.Exp Hematol2008-01-01T00:00:002008Generation of functional natural killer and dendritic cells in a human stromal-based serum-free culture system designed for cord blood expansion.18400364Colletti E, Lindstedt S, Park PJ, Almeida-Porada G, Porada CDExperimental hematologyColletti E, Lindstedt S, Park PJ, Almeida-Porada G, Porada CD. Early fetal gene delivery utilizes both central and peripheral mechanisms of tolerance induction. Exp Hematol. 2008 Jul; 36(7):816-22.Exp Hematol2008-04-08T00:00:002008Early fetal gene delivery utilizes both central and peripheral mechanisms of tolerance induction.19197149Yamagami T, Porada CD, Pardini RS, Zanjani ED, Almeida-Porada GCancer biology & therapyYamagami T, Porada CD, Pardini RS, Zanjani ED, Almeida-Porada G. Docosahexaenoic acid induces dose dependent cell death in an early undifferentiated subtype of acute myeloid leukemia cell line. . 2009 Feb; 8(4):331-7.2009-02-03T00:00:002009Docosahexaenoic acid induces dose dependent cell death in an early undifferentiated subtype of acute myeloid leukemia cell line.19301473Park PJ, Colletti E, Ozturk F, Wood JA, Tellez J, Almeida-Porada G, Porada CHuman gene therapyPark PJ, Colletti E, Ozturk F, Wood JA, Tellez J, Almeida-Porada G, Porada C. Factors determining the risk of inadvertent retroviral transduction of male germ cells after in utero gene transfer in sheep. Hum Gene Ther. 2009 Mar; 20(3):201-15.Hum Gene Ther2009-03-01T00:00:002009Factors determining the risk of inadvertent retroviral transduction of male germ cells after in utero gene transfer in sheep.19383418Colletti EJ, Airey JA, Liu W, Simmons PJ, Zanjani ED, Porada CD, Almeida-Porada GStem cell researchColletti EJ, Airey JA, Liu W, Simmons PJ, Zanjani ED, Porada CD, Almeida-Porada G. Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer. Stem Cell Res. 2009 Mar; 2(2):125-38.Stem Cell Res2008-09-16T00:00:002008Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer.20227460Goodrich AD, Ersek A, Varain NM, Groza D, Cenariu M, Thain DS, Almeida-Porada G, Porada CD, Zanjani EDExperimental hematologyGoodrich AD, Ersek A, Varain NM, Groza D, Cenariu M, Thain DS, Almeida-Porada G, Porada CD, Zanjani ED. In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells. Exp Hematol. 2010 Jun; 38(6):516-525.e4.Exp Hematol2010-03-12T00:00:002010In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells.20828588Porada CD, Almeida-Porada GAdvanced drug delivery reviewsPorada CD, Almeida-Porada G. Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery. Adv Drug Deliv Rev. 2010 Sep 30; 62(12):1156-66.Adv Drug Deliv Rev2010-09-07T00:00:002010Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery.21906573Porada CD, Sanada C, Kuo CJ, Colletti E, Mandeville W, Hasenau J, Zanjani ED, Moot R, Doering C, Spencer HT, Almeida-Porada GExperimental hematologyPorada CD, Sanada C, Kuo CJ, Colletti E, Mandeville W, Hasenau J, Zanjani ED, Moot R, Doering C, Spencer HT, Almeida-Porada G. Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC. Exp Hematol. 2011 Dec; 39(12):1124-1135.e4.Exp Hematol2011-09-08T00:00:002011Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC.22262359Ozturk F, Park PJ, Tellez J, Colletti E, Eiden MV, Almeida-Porada G, Porada CDThe journal of gene medicineOzturk F, Park PJ, Tellez J, Colletti E, Eiden MV, Almeida-Porada G, Porada CD. Expression levels of the PiT-2 receptor explain, in part, the gestational age-dependent alterations in transduction efficiency after in utero retroviral-mediated gene transfer. J Gene Med. 2012 Mar; 14(3):169-81.J Gene Med2012-03-01T00:00:002012Expression levels of the PiT-2 receptor explain, in part, the gestational age-dependent alterations in transduction efficiency after in utero retroviral-mediated gene transfer.23042590Sanada C, Kuo CJ, Colletti EJ, Soland M, Mokhtari S, Knovich MA, Owen J, Zanjani ED, Porada CD, Almeida-Porada GJournal of cellular physiologySanada C, Kuo CJ, Colletti EJ, Soland M, Mokhtari S, Knovich MA, Owen J, Zanjani ED, Porada CD, Almeida-Porada G. Mesenchymal stem cells contribute to endogenous FVIII:c production. J Cell Physiol. 2013 May; 228(5):1010-6.J Cell Physiol2013-05-01T00:00:002013Mesenchymal stem cells contribute to endogenous FVIII:c production.23152911Zakas PM, Gangadharan B, Almeida-Porada G, Porada CD, Spencer HT, Doering CBPloS oneZakas PM, Gangadharan B, Almeida-Porada G, Porada CD, Spencer HT, Doering CB. Development and characterization of recombinant ovine coagulation factor VIII. PLoS One. 2012; 7(11):e49481.PLoS One2012-11-09T00:00:002012Development and characterization of recombinant ovine coagulation factor VIII.12070011Tsai EJ, Malech HL, Kirby MR, Hsu AP, Seidel NE, Porada CD, Zanjani ED, Bodine DM, Puck JMBloodTsai EJ, Malech HL, Kirby MR, Hsu AP, Seidel NE, Porada CD, Zanjani ED, Bodine DM, Puck JM. Retroviral transduction of IL2RG into CD34(+) cells from X-linked severe combined immunodeficiency patients permits human T- and B-cell development in sheep chimeras. Blood. 2002 Jul 01; 100(1):72-9.Blood2002-07-01T00:00:002002Retroviral transduction of IL2RG into CD34(+) cells from X-linked severe combined immunodeficiency patients permits human T- and B-cell development in sheep chimeras.Biomedical Engineering12482508Almeida-Porada G, El Shabrawy D, Porada C, Zanjani EDExperimental hematologyAlmeida-Porada G, El Shabrawy D, Porada C, Zanjani ED. Differentiative potential of human metanephric mesenchymal cells. Exp Hematol. 2002 Dec; 30(12):1454-62.Exp Hematol2002-12-01T00:00:002002Differentiative potential of human metanephric mesenchymal cells.14979471Almeida-Porada G, Porada C, Zanjani EDInternational journal of hematologyAlmeida-Porada G, Porada C, Zanjani ED. Plasticity of human stem cells in the fetal sheep model of human stem cell transplantation. Int J Hematol. 2004 Jan; 79(1):1-6.Int J Hematol2004-01-01T00:00:002004Plasticity of human stem cells in the fetal sheep model of human stem cell transplantation.15023887Airey JA, Almeida-Porada G, Colletti EJ, Porada CD, Chamberlain J, Movsesian M, Sutko JL, Zanjani EDCirculationAirey JA, Almeida-Porada G, Colletti EJ, Porada CD, Chamberlain J, Movsesian M, Sutko JL, Zanjani ED. Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart. Circulation. 2004 Mar 23; 109(11):1401-7.Circulation2004-03-15T00:00:002004Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart.15231580Almeida-Porada G, Porada CD, Chamberlain J, Torabi A, Zanjani EDBloodAlmeida-Porada G, Porada CD, Chamberlain J, Torabi A, Zanjani ED. Formation of human hepatocytes by human hematopoietic stem cells in sheep. Blood. 2004 Oct 15; 104(8):2582-90.Blood2004-07-01T00:00:002004Formation of human hepatocytes by human hematopoietic stem cells in sheep.15250043Porada GA, Porada C, Zanjani EDYonsei medical journalPorada GA, Porada C, Zanjani ED. The fetal sheep: a unique model system for assessing the full differentiative potential of human stem cells. Yonsei Med J. 2004 Jun 30; 45 Suppl:7-14.Yonsei Med J2004-06-30T00:00:002004The fetal sheep: a unique model system for assessing the full differentiative potential of human stem cells.15668140Porada CD, Park PJ, Almeida-Porada G, Liu W, Ozturk F, Glimp HA, Zanjani EDMolecular therapy : the journal of the American Society of Gene TherapyPorada CD, Park PJ, Almeida-Porada G, Liu W, Ozturk F, Glimp HA, Zanjani ED. Gestational age of recipient determines pattern and level of transgene expression following in utero retroviral gene transfer. Mol Ther. 2005 Feb; 11(2):284-93.Mol Ther2005-02-01T00:00:002005Gestational age of recipient determines pattern and level of transgene expression following in utero retroviral gene transfer.16084775Porada CD, Park PJ, Tellez J, Ozturk F, Glimp HA, Almeida-Porada G, Zanjani EDMolecular therapy : the journal of the American Society of Gene TherapyPorada CD, Park PJ, Tellez J, Ozturk F, Glimp HA, Almeida-Porada G, Zanjani ED. Male germ-line cells are at risk following direct-injection retroviral-mediated gene transfer in utero. Mol Ther. 2005 Oct; 12(4):754-62.Mol Ther2005-10-01T00:00:002005Male germ-line cells are at risk following direct-injection retroviral-mediated gene transfer in utero.17705296Chamberlain J, Yamagami T, Colletti E, Theise ND, Desai J, Frias A, Pixley J, Zanjani ED, Porada CD, Almeida-Porada GHepatology (Baltimore, Md.)Chamberlain J, Yamagami T, Colletti E, Theise ND, Desai J, Frias A, Pixley J, Zanjani ED, Porada CD, Almeida-Porada G. Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep. Hepatology. 2007 Dec; 46(6):1935-45.Hepatology2007-12-01T00:00:002007Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep.18220880Porada CD, Zanjani ED, Almeida-Porad GCurrent stem cell research & therapyPorada CD, Zanjani ED, Almeida-Porad G. 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Hepatology. 2012 Sep; 56(3):1086-96.Hepatology2012-08-02T00:00:002012Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model.22666319Soland MA, Bego MG, Colletti E, Porada CD, Zanjani ED, St Jeor S, Almeida-Porada GPloS oneSoland MA, Bego MG, Colletti E, Porada CD, Zanjani ED, St Jeor S, Almeida-Porada G. Modulation of human mesenchymal stem cell immunogenicity through forced expression of human cytomegalovirus us proteins. PLoS One. 2012; 7(5):e36163.PLoS One2012-05-30T00:00:002012Modulation of human mesenchymal stem cell immunogenicity through forced expression of human cytomegalovirus us proteins.23555976Soland MA, Bego M, Colletti E, Zanjani ED, St Jeor S, Porada CD, Almeida-Porada GPloS oneSoland MA, Bego M, Colletti E, Zanjani ED, St Jeor S, Porada CD, Almeida-Porada G. Mesenchymal stem cells engineered to inhibit complement-mediated damage. PLoS One. 2013; 8(3):e60461.PLoS One2013-03-26T00:00:002013Mesenchymal stem cells engineered to inhibit complement-mediated damage.Authorship 34456923413357Colletti E, El Shabrawy D, Soland M, Yamagami T, Mokhtari S, Osborne C, Schlauch K, Zanjani ED, Porada CD, Almeida-Porada GFASEB journal : official publication of the Federation of American Societies for Experimental BiologyColletti E, El Shabrawy D, Soland M, Yamagami T, Mokhtari S, Osborne C, Schlauch K, Zanjani ED, Porada CD, Almeida-Porada G. EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool. FASEB J. 2013 Jun; 27(6):2111-21.FASEB J2013-02-14T00:00:002013EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool.D003359Phenomena10130.983186Cosmic RadiationD012190Living Beings9260.986008RetroviridaeD012756Living Beings352180.93521SheepD014161PhysiologyProcedures19420.98306Transduction, GeneticD044982Anatomy331610.856521Mesenchymal Stem Cells