TNF-Related Apoptosis-Inducing Ligand
"TNF-Related Apoptosis-Inducing Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.
| Descriptor ID |
D053221
|
| MeSH Number(s) |
D12.644.276.374.750.625 D12.644.276.972.625 D12.776.467.374.750.625 D12.776.467.972.625 D23.529.374.750.625 D23.529.972.625
|
| Concept/Terms |
TNF-Related Apoptosis-Inducing Ligand- TNF-Related Apoptosis-Inducing Ligand
- Apoptosis-Inducing Ligand, TNF-Related
- TNF Related Apoptosis Inducing Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 10
- TNF Superfamily, Member 10
- TRAIL Protein
- Apo-2 Ligand
- Apo 2 Ligand
- Apo-2L Protein
- Apo 2L Protein
|
Below are MeSH descriptors whose meaning is more general than "TNF-Related Apoptosis-Inducing Ligand".
Below are MeSH descriptors whose meaning is more specific than "TNF-Related Apoptosis-Inducing Ligand".
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "TNF-Related Apoptosis-Inducing Ligand" by people in Profiles.