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Clinical and Translational Science Institute

Keywords
Last Name

Thomas D. Shupe, Ph.D.

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentWF Institute for Regen Medicine
Address
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hunsberger JG, Shupe T, Atala A. An Industry-Driven Roadmap for Manufacturing in Regenerative Medicine. Stem Cells Transl Med. 2018 Aug; 7(8):564-568. PMID: 30009571.
      View in: PubMed
    2. Forsythe SD, Devarasetty M, Shupe T, Bishop C, Atala A, Soker S, Skardal A. Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids. Front Public Health. 2018; 6:103. PMID: 29755963.
      View in: PubMed
    3. Skardal A, Murphy SV, Devarasetty M, Mead I, Kang HW, Seol YJ, Shrike Zhang Y, Shin SR, Zhao L, Aleman J, Hall AR, Shupe TD, Kleensang A, Dokmeci MR, Jin Lee S, Jackson JD, Yoo JJ, Hartung T, Khademhosseini A, Soker S, Bishop CE, Atala A. Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform. Sci Rep. 2017 08 18; 7(1):8837. PMID: 28821762.
      View in: PubMed
    4. Devarasetty M, Forsythe S, Shupe TD, Soker S, Bishop CE, Atala A, Skardal A. Optical Tracking and Digital Quantification of Beating Behavior in Bioengineered Human Cardiac Organoids. Biosensors (Basel). 2017 Jun 23; 7(3). PMID: 28644395.
      View in: PubMed
    5. Zhang YS, Aleman J, Shin SR, Kilic T, Kim D, Mousavi Shaegh SA, Massa S, Riahi R, Chae S, Hu N, Avci H, Zhang W, Silvestri A, Sanati Nezhad A, Manbohi A, De Ferrari F, Polini A, Calzone G, Shaikh N, Alerasool P, Budina E, Kang J, Bhise N, Ribas J, Pourmand A, Skardal A, Shupe T, Bishop CE, Dokmeci MR, Atala A, Khademhosseini A. Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):E2293-E2302. PMID: 28265064.
      View in: PubMed
    6. Zhang YS, Arneri A, Bersini S, Shin SR, Zhu K, Goli-Malekabadi Z, Aleman J, Colosi C, Busignani F, Dell'Erba V, Bishop C, Shupe T, Demarchi D, Moretti M, Rasponi M, Dokmeci MR, Atala A, Khademhosseini A. Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip. Biomaterials. 2016 12; 110:45-59. PMID: 27710832.
      View in: PubMed
    7. Skardal A, Shupe T, Atala A. Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling. Drug Discov Today. 2016 09; 21(9):1399-1411. PMID: 27422270.
      View in: PubMed
    8. Skardal A, Devarasetty M, Kang HW, Seol YJ, Forsythe SD, Bishop C, Shupe T, Soker S, Atala A. Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink. J Vis Exp. 2016 Apr 21; (110):e53606. PMID: 27166839.
      View in: PubMed
    9. Bhise NS, Manoharan V, Massa S, Tamayol A, Ghaderi M, Miscuglio M, Lang Q, Shrike Zhang Y, Shin SR, Calzone G, Annabi N, Shupe TD, Bishop CE, Atala A, Dokmeci MR, Khademhosseini A. A liver-on-a-chip platform with bioprinted hepatic spheroids. Biofabrication. 2016 Jan 12; 8(1):014101. PMID: 26756674.
      View in: PubMed
    10. Deegan DB, Zimmerman C, Skardal A, Atala A, Shupe TD. Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology. J Mech Behav Biomed Mater. 2015 Mar; 55:87-103. PMID: 26569044.
      View in: PubMed
    11. Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A. A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. Acta Biomater. 2015 Oct; 25:24-34. PMID: 26210285.
      View in: PubMed
    12. Shupe TD, Petersen BE. Liver regeneration: A consequence of complex, well-orchestrated signals. Hepatology. 2015 Aug; 62(2):644-5. PMID: 25953495.
      View in: PubMed
    13. Ko IK, Peng L, Peloso A, Smith CJ, Dhal A, Deegan DB, Zimmerman C, Clouse C, Zhao W, Shupe TD, Soker S, Yoo JJ, Atala A. Bioengineered transplantable porcine livers with re-endothelialized vasculature. Biomaterials. 2015 Feb; 40:72-9. PMID: 25433603.
      View in: PubMed
    14. Mirmalek-Sani SH, Sullivan DC, Zimmerman C, Shupe TD, Petersen BE. Immunogenicity of decellularized porcine liver for bioengineered hepatic tissue. Am J Pathol. 2013 Aug; 183(2):558-65. PMID: 23747949.
      View in: PubMed
    15. Orlando G, Domínguez-Bendala J, Shupe T, Bergman C, Bitar KN, Booth C, Carbone M, Koch KL, Lerut JP, Neuberger JM, Petersen B, Ricordi C, Atala A, Stratta RJ, Soker S. Cell and organ bioengineering technology as applied to gastrointestinal diseases. Gut. 2013 May; 62(5):774-86. PMID: 22267591.
      View in: PubMed
    16. Oh SH, Darwiche H, Cho JH, Shupe T, Petersen BE. Characterization of a novel functional protein in the pancreatic islet: islet homeostasis protein regulation of glucagon synthesis in a cells. Pancreas. 2012 Jan; 41(1):22-30. PMID: 22143342.
      View in: PubMed
    17. Darwiche H, Oh SH, Steiger-Luther NC, Williams JM, Pintilie DG, Shupe TD, Petersen BE. Inhibition of Notch signaling affects hepatic oval cell response in rat model of 2AAF-PH. Hepat Med. 2011 Sep 01; 3:89-98. PMID: 21927552.
      View in: PubMed
    18. Shupe T, Petersen BE. Potential applications for cell regulatory factors in liver progenitor cell therapy. Int J Biochem Cell Biol. 2011 Feb; 43(2):214-21. PMID: 20851776.
      View in: PubMed
    19. Pintilie DG, Shupe TD, Oh SH, Salganik SV, Darwiche H, Petersen BE. Hepatic stellate cells' involvement in progenitor-mediated liver regeneration. Lab Invest. 2010 Aug; 90(8):1199-208. PMID: 20440274.
      View in: PubMed
    20. Williams JM, Oh SH, Jorgensen M, Steiger N, Darwiche H, Shupe T, Petersen BE. The role of the Wnt family of secreted proteins in rat oval "stem" cell-based liver regeneration: Wnt1 drives differentiation. Am J Pathol. 2010 Jun; 176(6):2732-42. PMID: 20413689.
      View in: PubMed
    21. Shupe T, Williams M, Brown A, Willenberg B, Petersen BE. Method for the decellularization of intact rat liver. Organogenesis. 2010 Apr-Jun; 6(2):134-6. PMID: 20885860.
      View in: PubMed
    22. Salganik SV, Weinstein DA, Shupe TD, Salganik M, Pintilie DG, Petersen BE. A detailed characterization of the adult mouse model of glycogen storage disease Ia. Lab Invest. 2009 Sep; 89(9):1032-42. PMID: 19581879.
      View in: PubMed
    23. Piscaglia AC, Shupe TD, Pani G, Tesori V, Gasbarrini A, Petersen BE. Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival. J Hepatol. 2009 Jul; 51(1):77-92. PMID: 19446912.
      View in: PubMed
    24. Shupe TD, Piscaglia AC, Oh SH, Gasbarrini A, Petersen BE. Isolation and characterization of hepatic stem cells, or "oval cells," from rat livers. Methods Mol Biol. 2009; 482:387-405. PMID: 19089369.
      View in: PubMed
    25. Petersen B, Shupe T. Location is everything: the liver stem cell niche. Hepatology. 2008 Jun; 47(6):1810-2. PMID: 18506878.
      View in: PubMed
    26. Ellor S, Shupe T, Petersen B. Stem cell therapy for inherited metabolic disorders of the liver. Exp Hematol. 2008 Jun; 36(6):716-725. PMID: 18375039.
      View in: PubMed
    27. Piscaglia AC, Shupe TD, Oh SH, Gasbarrini A, Petersen BE. Granulocyte-colony stimulating factor promotes liver repair and induces oval cell migration and proliferation in rats. Gastroenterology. 2007 Aug; 133(2):619-31. PMID: 17681181.
      View in: PubMed
    28. Jung Y, Oh SH, Zheng D, Shupe TD, Witek RP, Petersen BE. A potential role of somatostatin and its receptor SSTR4 in the migration of hepatic oval cells. Lab Invest. 2006 May; 86(5):477-89. PMID: 16534498.
      View in: PubMed
    29. Pi L, Oh SH, Shupe T, Petersen BE. Role of connective tissue growth factor in oval cell response during liver regeneration after 2-AAF/PHx in rats. Gastroenterology. 2005 Jun; 128(7):2077-88. PMID: 15940639.
      View in: PubMed
    30. Shupe T, Petersen BE. Evidence regarding a stem cell origin of hepatocellular carcinoma. Stem Cell Rev. 2005; 1(3):261-4. PMID: 17142863.
      View in: PubMed
    31. Shupe T, Sell S. Low hepatic glutathione S-transferase and increased hepatic DNA adduction contribute to increased tumorigenicity of aflatoxin B1 in newborn and partially hepatectomized mice. Toxicol Lett. 2004 Mar 14; 148(1-2):1-9. PMID: 15019083.
      View in: PubMed
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