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Clinical and Translational Science Institute

Keywords
Last Name

Raghunatha Yammani, Ph.D.

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentInternal Medicine - Molecular Medicine
Address
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    Other Positions
    TitleAssociate Professor
    InstitutionWake Forest School of Medicine
    DepartmentInternal Medicine-Rheumatology and Immunology

    TitleAssociate Professor
    InstitutionWake Forest School of Medicine
    DepartmentSurgical Sciences-Orthopaedics


    Collapse Research 
    Collapse research activities and funding
    R03AR061050     (YAMMANI, RAGHUNATHA R)Apr 1, 2011 - Mar 31, 2014
    NIH/NIAMS
    Invivo role of S100A4 in OA pathophysiology
    Role: Principal Investigator

    R21AR063835     (YAMMANI, RAGHUNATHA R)Jul 25, 2013 - Jun 30, 2015
    NIH/NIAMS
    ER Stress: Role in OA
    Role: Principal Investigator

    R01AR066105     (YAMMANI, RAGHUNATHA R)Jun 1, 2014 - May 31, 2019
    NIH/NIAMS
    Diet , ER stress and OA
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Mallik A, Yammani RR. Saturated fatty acid palmitate negatively regulates autophagy by promoting ATG5 protein degradation in meniscus cells. Biochem Biophys Res Commun. 2018 07 20; 502(3):370-374. PMID: 29852167.
      View in: PubMed
    2. Wood ST, Long DL, Reisz JA, Yammani RR, Burke EA, Klomsiri C, Poole LB, Furdui CM, Loeser RF. Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments. Arthritis Rheumatol. 2016 Jan; 68(1):117-26. PMID: 26314228; PMCID: PMC4849859 [Available on 01/01/17].
    3. Files DC, Liu C, Pereyra A, Wang ZM, Aggarwal NR, D'Alessio FR, Garibaldi BT, Mock JR, Singer BD, Feng X, Yammani RR, Zhang T, Lee AL, Philpott S, Lussier S, Purcell L, Chou J, Seeds M, King LS, Morris PE, Delbono O. Therapeutic exercise attenuates neutrophilic lung injury and skeletal muscle wasting. Sci Transl Med. 2015 Mar 11; 7(278):278ra32. PMID: 25761888; PMCID: PMC4820823.
    4. Yammani RR, Loeser RF. Brief report: stress-inducible nuclear protein 1 regulates matrix metalloproteinase 13 expression in human articular chondrocytes. Arthritis Rheumatol. 2014 May; 66(5):1266-71. PMID: 24497499; PMCID: PMC4034354.
    5. Yammani RR, Loeser RF. Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes. Arthritis Res Ther. 2012 Jan 30; 14(1):R23. PMID: 22289259; PMCID: PMC3392816.
    6. Yammani RR. S100 proteins in cartilage: role in arthritis. Biochim Biophys Acta. 2012 Apr; 1822(4):600-6. PMID: 22266138; PMCID: PMC3294013.
    7. Miranda KJ, Loeser RF, Yammani RR. Sumoylation and nuclear translocation of S100A4 regulate IL-1beta-mediated production of matrix metalloproteinase-13. J Biol Chem. 2010 Oct 08; 285(41):31517-24. PMID: 20685652; PMCID: PMC2951226.
    8. Yammani RR, Long D, Loeser RF. Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis Rheum. 2009 Mar; 60(3):792-800. PMID: 19248116; PMCID: PMC2676111.
    9. Cravero JD, Carlson CS, Im HJ, Yammani RR, Long D, Loeser RF. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis. Arthritis Rheum. 2009 Feb; 60(2):492-500. PMID: 19180501; PMCID: PMC2637941.
    10. Ahuja R, Yammani R, Bauer JA, Kalra S, Seetharam S, Seetharam B. Interactions of cubilin with megalin and the product of the amnionless gene (AMN): effect on its stability. Biochem J. 2008 Mar 01; 410(2):301-8. PMID: 17990981.
      View in: PubMed
    11. Bose S, Kalra S, Yammani RR, Ahuja R, Seetharam B. Plasma membrane delivery, endocytosis and turnover of transcobalamin receptor in polarized human intestinal epithelial cells. J Physiol. 2007 Jun 01; 581(Pt 2):457-66. PMID: 17347267; PMCID: PMC2075189.
    12. Yammani RR, Carlson CS, Bresnick AR, Loeser RF. Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products. Arthritis Rheum. 2006 Sep; 54(9):2901-11. PMID: 16948116.
      View in: PubMed
    13. Loeser RF, Yammani RR, Carlson CS, Chen H, Cole A, Im HJ, Bursch LS, Yan SD. Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. Arthritis Rheum. 2005 Aug; 52(8):2376-85. PMID: 16052547; PMCID: PMC1488730.
    14. Kalra S, Li N, Yammani RR, Seetharam S, Seetharam B. Cobalamin (vitamin B12) binding, phylogeny, and synteny of human transcobalamin. Arch Biochem Biophys. 2004 Nov 15; 431(2):189-96. PMID: 15488467.
      View in: PubMed
    15. Kalra S, Seetharam S, Yammani RR, Seetharam B. Rat transcobalamin: cloning and regulation of mRNA expression. J Physiol. 2004 Apr 15; 556(Pt 2):623-35. PMID: 14724191; PMCID: PMC1664936.
    16. Seetharam B, Yammani RR. Cobalamin transport proteins and their cell-surface receptors. Expert Rev Mol Med. 2003 Jun 13; 5(18):1-18. PMID: 14585166.
      View in: PubMed
    17. Vanamala SK, Seetharam S, Yammani RR, Seetharam B. Human transcobalamin II receptor binds to Staphylococcus aureus protein A: implications as to its structure and function. Arch Biochem Biophys. 2003 Mar 15; 411(2):204-14. PMID: 12623069.
      View in: PubMed
    18. Yammani RR, Sharma M, Seetharam S, Moulder JE, Dahms NM, Seetharam B. Loss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiation. Am J Physiol Regul Integr Comp Physiol. 2002 Aug; 283(2):R339-46. PMID: 12121845.
      View in: PubMed
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