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Clinical and Translational Science Institute

Keywords
Last Name

Robert Willson Hurley, M.D., Ph.D.

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentAnesthesiology
Address
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    1F30DA005784-01     (HURLEY, ROBERT W)Mar 29, 1997
    NIH
    ANALGESIA, SUPRASPINAL OPIOIDS AND INFLAMMATORY PAIN
    Role: Principal Investigator

    F30DA005784     (HURLEY, ROBERT W)Mar 29, 1997
    NIH/NIDA
    ANALGESIA, SUPRASPINAL OPIOIDS AND INFLAMMATORY PAIN
    Role: Principal Investigator

    5F30DA005784-02     (HURLEY, ROBERT W)Mar 20, 1998
    NIH
    ANALGESIA, SUPRASPINAL OPIOIDS AND INFLAMMATORY PAIN
    Role: Principal Investigator

    5F30DA005784-03     (HURLEY, ROBERT W)Mar 20, 1999
    NIH
    ANALGESIA, SUPRASPINAL OPIOIDS AND INFLAMMATORY PAIN
    Role: Principal Investigator

    5F30DA005784-04     (HURLEY, ROBERT W)Mar 20, 2000
    NIH
    ANALGESIA, SUPRASPINAL OPIOIDS AND INFLAMMATORY PAIN
    Role: Principal Investigator

    5F30DA005784-05     (HURLEY, ROBERT W)Apr 1, 2001
    NIH
    ANALGESIA, SUPRASPINAL OPIOIDS AND INFLAMMATORY PAIN
    Role: Principal Investigator

    5F30DA005784-06     (HURLEY, ROBERT W)Mar 20, 2002
    NIH
    ANALGESIA, SUPRASPINAL OPIOIDS AND INFLAMMATORY PAIN
    Role: Principal Investigator

    R01HS023306     (HARLE, CHRISTOPHER ALBERT)Sep 30, 2015 - Jul 31, 2019
    NIH
    Designing User-Centered Decision Support Tools for Chronic Pain in Primary Care
    Role: Co-Investigator

    R21DA046085     (HARLE, CHRIS ALBERT)Sep 1, 2017 - Aug 31, 2019
    NIH
    Nudging Primary Care Providers toward Guideline-Recommended Opioid Prescribing through Easier and More Convenient EHR Information Design
    Role: Co-Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cohen SP, Bhatia A, Buvanendran A, Schwenk ES, Wasan AD, Hurley RW, Viscusi ER, Narouze S, Davis FN, Ritchie EC, Lubenow TR, Hooten WM. Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Chronic Pain From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists. Reg Anesth Pain Med. 2018 Jul; 43(5):521-546. PMID: 29870458.
      View in: PubMed
    2. Schwenk ES, Viscusi ER, Buvanendran A, Hurley RW, Wasan AD, Narouze S, Bhatia A, Davis FN, Hooten WM, Cohen SP. Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists. Reg Anesth Pain Med. 2018 Jul; 43(5):456-466. PMID: 29870457.
      View in: PubMed
    3. Karafin MS, Singavi A, Hussain J, Wandersee N, Heinrich T, Hurley RW, Zhang L, Simpson P, Field JJ. Predictive factors of daily opioid use and quality of life in adults with sickle cell disease. Hematology. 2018 Dec; 23(10):856-863. PMID: 29848208.
      View in: PubMed
    4. Meredith C.B. Adams, Mark C. Bicket, Jamie D. Murphy, Christopher L. Wub, Robert W. Hurley. Opportunities and challenges for junior conducting pain clinical trials. Pain Reports. 2018; (e639).
    5. Clark MR, Hurley RW, Adams MCB. Re-assessing the Validity of the Opioid Risk Tool in a Tertiary Academic Pain Management Center Population. Pain Med. 2018 Feb 02. PMID: 29408996.
      View in: PubMed
    6. Nicol AL, Hurley RW, Benzon HT. Alternatives to Opioids in the Pharmacologic Management of Chronic Pain Syndromes: A Narrative Review of Randomized, Controlled, and Blinded Clinical Trials. Anesth Analg. 2017 11; 125(5):1682-1703. PMID: 29049114.
      View in: PubMed
    7. Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions. Pain Med. 2017 05 01; 18(5):947-958. PMID: 28482098.
      View in: PubMed
    8. Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions. J Pain. 2017 May; 18(5):479-489. PMID: 28495013.
      View in: PubMed
    9. Harle CA, Marlow NM, Schmidt SO, Shuster JJ, Listhaus A, Fillingim RB, Hurley RW. The effect of EHR-integrated patient-reported outcomes on satisfaction with chronic pain care. Am J Manag Care. 2016 Dec 01; 22(12):e403-e408. PMID: 27982672.
      View in: PubMed
    10. Harle CA, Lipori G, Hurley RW. Collecting, Integrating, and Disseminating Patient-Reported Outcomes for Research in a Learning Healthcare System. EGEMS (Wash DC). 2016; 4(1):1240. PMID: 27563683.
      View in: PubMed
    11. Titsworth WL, Abram J, Guin P, Herman MA, West J, Davis NW, Bushwitz J, Hurley RW, Seubert CN. A prospective time-series quality improvement trial of a standardized analgesia protocol to reduce postoperative pain among neurosurgery patients. J Neurosurg. 2016 12; 125(6):1523-1532. PMID: 26967774.
      View in: PubMed
    12. Bicket MC, Hurley RW, Moon JY, Brummett CM, Hanling S, Huntoon MA, van Zundert J, Cohen SP. The Development and Validation of a Quality Assessment and Rating of Technique for Injections of the Spine (AQUARIUS). Reg Anesth Pain Med. 2016 Jan-Feb; 41(1):80-5. PMID: 26655218.
      View in: PubMed
    13. Kisaalita NR, Hurley RW, Staud R, Robinson ME. Placebo Use in Pain Management: A Mechanism-Based Educational Intervention Enhances Placebo Treatment Acceptability. J Pain. 2016 Feb; 17(2):257-69. PMID: 26604097; PMCID: PMC4738022 [Available on 02/01/17].
    14. Anderson RJ, Hurley RW, Staud R, Robinson ME. Cognitive-Motivational Influences on Health Behavior Change in Adults with Chronic Pain. Pain Med. 2016 Jun; 17(6):1079-1093. PMID: 26441145.
      View in: PubMed
    15. Harle CA, Listhaus A, Covarrubias CM, Schmidt SO, Mackey S, Carek PJ, Fillingim RB, Hurley RW. Overcoming barriers to implementing patient-reported outcomes in an electronic health record: a case report. J Am Med Inform Assoc. 2016 Jan; 23(1):74-9. PMID: 26159464.
      View in: PubMed
    16. Tighe PJ, Harle CA, Hurley RW, Aytug H, Boezaart AP, Fillingim RB. Teaching a Machine to Feel Postoperative Pain: Combining High-Dimensional Clinical Data with Machine Learning Algorithms to Forecast Acute Postoperative Pain. Pain Med. 2015 Jul; 16(7):1386-401. PMID: 26031220; PMCID: PMC4504764.
    17. Chang KL, Fillingim R, Hurley RW, Schmidt S. Chronic pain management: evaluation of chronic pain. FP Essent. 2015 May; 432:11-20. PMID: 25970868.
      View in: PubMed
    18. Chang KL, Fillingim R, Hurley RW, Schmidt S. Chronic pain management: nonpharmacological therapies for chronic pain. FP Essent. 2015 May; 432:21-6. PMID: 25970869.
      View in: PubMed
    19. Chang KL, Fillingim R, Hurley RW, Schmidt S. Chronic pain management: pharmacotherapy for chronic pain. FP Essent. 2015 May; 432:27-38. PMID: 25970870.
      View in: PubMed
    20. Chang KL, Fillingim R, Hurley RW, Schmidt S. Chronic pain management: legal and licensure issues. FP Essent. 2015 May; 432:39-42. PMID: 25970871.
      View in: PubMed
    21. Harle CA, Bauer SE, Hoang HQ, Cook RL, Hurley RW, Fillingim RB. Decision support for chronic pain care: how do primary care physicians decide when to prescribe opioids? a qualitative study. BMC Fam Pract. 2015 Apr 14; 16:48. PMID: 25884340; PMCID: PMC4399157.
    22. Hulata DF, Le-Wendling L, Boezaart AP, Hurley RW. Stellate ganglion local anesthetic blockade and neurolysis for the treatment of refractory ventricular fibrillation. A A Case Rep. 2015 Mar 01; 4(5):49-51. PMID: 25730409.
      View in: PubMed
    23. Zaremski JL, Herman DC, Clugston JR, Hurley RW, Ahn AH. Occipital neuralgia as a sequela of sports concussion: a case series and review of the literature. Curr Sports Med Rep. 2015 Jan; 14(1):16-9. PMID: 25574876; PMCID: PMC4475344.
    24. Cohen SP, Hameed H, Pasquina PF, Hurley RW. Sedation for diagnostic injections: prioritizing patient interests. Pain Med. 2014 Nov; 15(11):1980-1. PMID: 25287941.
      View in: PubMed
    25. Vincent HK, George SZ, Seay AN, Vincent KR, Hurley RW. Resistance exercise, disability, and pain catastrophizing in obese adults with back pain. Med Sci Sports Exerc. 2014 Sep; 46(9):1693-701. PMID: 25133997; PMCID: PMC4137474.
    26. Verdun AV, Cohen SP, Williams BS, Hurley RW. Pneumocephalus after lumbar epidural steroid injection: a case report and review of the literature. A A Case Rep. 2014 Jul 01; 3(1):9-13. PMID: 25612267.
      View in: PubMed
    27. Bunch JR, Goldstein HV, Hurley RW. Complete coverage of phantom limb and stump pain with constant current SCS system: a case report and review of the literature. Pain Pract. 2015 Jan; 15(1):E20-6. PMID: 24919840.
      View in: PubMed
    28. Cohen SP, Hameed H, Kurihara C, Pasquina PF, Patel AM, Babade M, Griffith SR, Erdek ME, Jamison DE, Hurley RW. The effect of sedation on the accuracy and treatment outcomes for diagnostic injections: a randomized, controlled, crossover study. Pain Med. 2014 Apr; 15(4):588-602. PMID: 24524866.
      View in: PubMed
    29. Tighe PJ, Fillingim RB, Hurley RW. Geospatial analysis of hospital consumer assessment of healthcare providers and systems pain management experience scores in U.S. hospitals. Pain. 2014 May; 155(5):1016-26. PMID: 24525273; PMCID: PMC4086258.
    30. Hurley RW, Zhao K, Tighe PJ, Ko PS, Pronovost PJ, Wu CL. Examination of publications from academic anesthesiology faculty in the United States. Anesth Analg. 2014 Jan; 118(1):192-9. PMID: 24149582.
      View in: PubMed
    31. Lee F, Jamison DE, Hurley RW, Cohen SP. Epidural lysis of adhesions. Korean J Pain. 2014 Jan; 27(1):3-15. PMID: 24478895; PMCID: PMC3903797.
    32. Vincent HK, Vincent KR, Seay AN, Conrad BP, Hurley RW, George SZ. Back strength predicts walking improvement in obese, older adults with chronic low back pain. PM R. 2014 May; 6(5):418-26. PMID: 24211698; PMCID: PMC4013252.
    33. Vincent HK, Adams MC, Vincent KR, Hurley RW. Musculoskeletal pain, fear avoidance behaviors, and functional decline in obesity: potential interventions to manage pain and maintain function. Reg Anesth Pain Med. 2013 Nov-Dec; 38(6):481-91. PMID: 24141874.
      View in: PubMed
    34. Hurley RW, Adams MC, Benzon HT. Neuropathic pain: treatment guidelines and updates. Curr Opin Anaesthesiol. 2013 Oct; 26(5):580-7. PMID: 23995060.
      View in: PubMed
    35. Vincent HK, Seay AN, Montero C, Conrad BP, Hurley RW, Vincent KR. Kinesiophobia and fear-avoidance beliefs in overweight older adults with chronic low-back pain: relationship to walking endurance--part II. Am J Phys Med Rehabil. 2013 May; 92(5):439-45. PMID: 23478452; PMCID: PMC3647684.
    36. Vincent HK, Seay AN, Montero C, Conrad BP, Hurley RW, Vincent KR. Functional pain severity and mobility in overweight older men and women with chronic low-back pain--part I. Am J Phys Med Rehabil. 2013 May; 92(5):430-8. PMID: 23478453; PMCID: PMC3676903.
    37. McGreevy K, Hurley RW, Erdek MA, Aner MM, Li S, Cohen SP. The effectiveness of repeat celiac plexus neurolysis for pancreatic cancer: a pilot study. Pain Pract. 2013 Feb; 13(2):89-95. PMID: 22568823.
      View in: PubMed
    38. Vincent HK, Heywood K, Connelly J, Hurley RW. Obesity and weight loss in the treatment and prevention of osteoarthritis. PM R. 2012 May; 4(5 Suppl):S59-67. PMID: 22632704; PMCID: PMC3623013.
    39. Vincent HK, Vincent KR, Seay AN, Hurley RW. Functional impairment in obesity: a focus on knee and back pain. Pain Manag. 2011 Sep; 1(5):427-39. PMID: 24645710.
      View in: PubMed
    40. Liu SS, Togioka BM, Hurley RW, Vu CM, Hanna MN, Murphy JD, Wu CL. Methodological quality of randomized controlled trials of postoperative epidural analgesia: validation of the Epidural Analgesia Trial Checklist as a specific instrument to evaluate methodology. Reg Anesth Pain Med. 2010 Nov-Dec; 35(6):549-55. PMID: 20975473.
      View in: PubMed
    41. Bailey JA, Hurley RW, Gold MS. Crossroads of pain and addiction. Pain Med. 2010 Dec; 11(12):1803-18. PMID: 21040437.
      View in: PubMed
    42. Gupta A, Daigle S, Mojica J, Hurley RW. Patient perception of pain care in hospitals in the United States. J Pain Res. 2009 Nov 13; 2:157-64. PMID: 21197302; PMCID: PMC3004628.
    43. Brummett CM, Williams BS, Hurley RW, Erdek MA. A prospective, observational study of the relationship between body mass index and depth of the epidural space during lumbar transforaminal epidural steroid injection. Reg Anesth Pain Med. 2009 Mar-Apr; 34(2):100-5. PMID: 19282707; PMCID: PMC2715548.
    44. Hurley RW, Lesley MR, Adams MC, Brummett CM, Wu CL. Pregabalin as a treatment for painful diabetic peripheral neuropathy: a meta-analysis. Reg Anesth Pain Med. 2008 Sep-Oct; 33(5):389-94. PMID: 18774507.
      View in: PubMed
    45. Cohen SP, Hurley RW, Buckenmaier CC, Kurihara C, Morlando B, Dragovich A. Randomized placebo-controlled study evaluating lateral branch radiofrequency denervation for sacroiliac joint pain. Anesthesiology. 2008 Aug; 109(2):279-88. PMID: 18648237; PMCID: PMC2666931.
    46. Hurley RW, Adams MC. Sex, gender, and pain: an overview of a complex field. Anesth Analg. 2008 Jul; 107(1):309-17. PMID: 18635502; PMCID: PMC2715547.
    47. Cohen SP, Hurley RW. The ability of diagnostic spinal injections to predict surgical outcomes. Anesth Analg. 2007 Dec; 105(6):1756-75, table of contents. PMID: 18042881.
      View in: PubMed
    48. Cohen SP, Bajwa ZH, Kraemer JJ, Dragovich A, Williams KA, Stream J, Sireci A, McKnight G, Hurley RW. Factors predicting success and failure for cervical facet radiofrequency denervation: a multi-center analysis. Reg Anesth Pain Med. 2007 Nov-Dec; 32(6):495-503. PMID: 18035295.
      View in: PubMed
    49. Cohen SP, Wenzell D, Hurley RW, Kurihara C, Buckenmaier CC, Griffith S, Larkin TM, Dahl E, Morlando BJ. A double-blind, placebo-controlled, dose-response pilot study evaluating intradiscal etanercept in patients with chronic discogenic low back pain or lumbosacral radiculopathy. Anesthesiology. 2007 Jul; 107(1):99-105. PMID: 17585221.
      View in: PubMed
    50. Cohen SP, Stojanovic MP, Crooks M, Kim P, Schmidt RK, Shields CH, Croll S, Hurley RW. Lumbar zygapophysial (facet) joint radiofrequency denervation success as a function of pain relief during diagnostic medial branch blocks: a multicenter analysis. Spine J. 2008 May-Jun; 8(3):498-504. PMID: 17662665.
      View in: PubMed
    51. Sykes KT, White SR, Hurley RW, Mizoguchi H, Tseng LF, Hammond DL. Mechanisms responsible for the enhanced antinociceptive effects of micro-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain. J Pharmacol Exp Ther. 2007 Aug; 322(2):813-21. PMID: 17494863.
      View in: PubMed
    52. Cohen SP, Hurley RW, Christo PJ, Winkley J, Mohiuddin MM, Stojanovic MP. Clinical predictors of success and failure for lumbar facet radiofrequency denervation. Clin J Pain. 2007 Jan; 23(1):45-52. PMID: 17277644.
      View in: PubMed
    53. Cohen SP, Sireci A, Wu CL, Larkin TM, Williams KA, Hurley RW. Pulsed radiofrequency of the dorsal root ganglia is superior to pharmacotherapy or pulsed radiofrequency of the intercostal nerves in the treatment of chronic postsurgical thoracic pain. Pain Physician. 2006 Jul; 9(3):227-35. PMID: 16886031.
      View in: PubMed
    54. Hurley RW, Cohen SP, Williams KA, Rowlingson AJ, Wu CL. The analgesic effects of perioperative gabapentin on postoperative pain: a meta-analysis. Reg Anesth Pain Med. 2006 May-Jun; 31(3):237-47. PMID: 16701190.
      View in: PubMed
    55. Wu CL, Hurley RW, Anderson GF, Herbert R, Rowlingson AJ, Fleisher LA. Effect of postoperative epidural analgesia on morbidity and mortality following surgery in medicare patients. Reg Anesth Pain Med. 2004 Nov-Dec; 29(6):525-33; discussion 515-9. PMID: 15635510.
      View in: PubMed
    56. Block BM, Hurley RW, Raja SN. Mechanism-based therapies for pain. Drug News Perspect. 2004 Apr; 17(3):172-86. PMID: 15179452.
      View in: PubMed
    57. Hurley RW, Banfor P, Hammond DL. Spinal pharmacology of antinociception produced by microinjection of mu or delta opioid receptor agonists in the ventromedial medulla of the rat. Neuroscience. 2003; 118(3):789-96. PMID: 12710986.
      View in: PubMed
    58. Hurley RW, Chatterjea D, Rose Feng M, Taylor CP, Hammond DL. Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia. Anesthesiology. 2002 Nov; 97(5):1263-73. PMID: 12411814.
      View in: PubMed
    59. Parra MC, Nguyen TN, Hurley RW, Hammond DL. Persistent inflammatory nociception increases levels of dynorphin 1-17 in the spinal cord, but not in supraspinal nuclei involved in pain modulation. J Pain. 2002 Aug; 3(4):330-6. PMID: 14622757.
      View in: PubMed
    60. Oh SB, Tran PB, Gillard SE, Hurley RW, Hammond DL, Miller RJ. Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons. J Neurosci. 2001 Jul 15; 21(14):5027-35. PMID: 11438578.
      View in: PubMed
    61. Ackley MA, Hurley RW, Virnich DE, Hammond DL. A cellular mechanism for the antinociceptive effect of a kappa opioid receptor agonist. Pain. 2001 Apr; 91(3):377-88. PMID: 11275396.
      View in: PubMed
    62. Hurley RW, Hammond DL. Contribution of endogenous enkephalins to the enhanced analgesic effects of supraspinal mu opioid receptor agonists after inflammatory injury. J Neurosci. 2001 Apr 01; 21(7):2536-45. PMID: 11264327.
      View in: PubMed
    63. Hurley RW, Hammond DL. The analgesic effects of supraspinal mu and delta opioid receptor agonists are potentiated during persistent inflammation. J Neurosci. 2000 Feb 01; 20(3):1249-59. PMID: 10648729.
      View in: PubMed
    64. Grabow TS, Hurley RW, Banfor PN, Hammond DL. Supraspinal and spinal delta(2) opioid receptor-mediated antinociceptive synergy is mediated by spinal alpha(2) adrenoceptors. Pain. 1999 Oct; 83(1):47-55. PMID: 10506671.
      View in: PubMed
    65. Hurley RW, Grabow TS, Tallarida RJ, Hammond DL. Interaction between medullary and spinal delta1 and delta2 opioid receptors in the production of antinociception in the rat. J Pharmacol Exp Ther. 1999 May; 289(2):993-9. PMID: 10215679.
      View in: PubMed
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