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Clinical and Translational Science Institute

Keywords
Last Name

Michael Thomas Munley, Ph.D.

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentRadiation Oncology
Address
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentRadiologic Sciences-Medical Engineering


    Collapse Research 
    Collapse research activities and funding
    R01CA136910     (MUNLEY, MICHAEL)May 5, 2009 - Feb 28, 2013
    NIH/NCI
    Effects of Low Dose CT Radiation on Lung Tumorigenesis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hughes RT, McTyre ER, LeCompte M, Cramer CK, Munley MT, Laxton AW, Tatter SB, Ruiz J, Pasche B, Watabe K, Chan MD. Clinical Outcomes of Upfront Stereotactic Radiosurgery Alone for Patients With 5 to 15 Brain Metastases. Neurosurgery. 2018 Jul 06. PMID: 29982831.
      View in: PubMed
    2. Dohm A, McTyre ER, Okoukoni C, Henson A, Cramer CK, LeCompte MC, Ruiz J, Munley MT, Qasem S, Lo HW, Xing F, Watabe K, Laxton AW, Tatter SB, Chan MD. Staged Stereotactic Radiosurgery for Large Brain Metastases: Local Control and Clinical Outcomes of a One-Two Punch Technique. Neurosurgery. 2018 Jul 01; 83(1):114-121. PMID: 28973432.
      View in: PubMed
    3. Soike MH, McTyre ER, Hughes RT, Farris M, Cramer CK, LeCompte MC, Lanier CM, Ruiz J, Su J, Watabe K, Bourland JD, Munley MT, O'Neill S, Laxton AW, Tatter SB, Chan MD. Initial brain metastasis velocity: does the rate at which cancers first seed the brain affect outcomes? J Neurooncol. 2018 Sep; 139(2):461-467. PMID: 29740743.
      View in: PubMed
    4. Farris M, McTyre ER, Okoukoni C, Dugan G, Johnson BJ, Blackstock AW, Munley MT, Bourland JD, Cline JM, Willey JS. Cortical Thinning and Structural Bone Changes in Non-Human Primates after Single-Fraction Whole-Chest Irradiation. Radiat Res. 2018 07; 190(1):63-71. PMID: 29738279.
      View in: PubMed
    5. Taylor JM, McTyre ER, Tatter SB, Laxton AW, Munley MT, Chan MD, Cramer CK. Gamma Knife Stereotactic Radiosurgery for the Treatment of Brain Metastases from Primary Tumors of the Urinary Bladder. Stereotact Funct Neurosurg. 2018; 96(2):108-112. PMID: 29698968.
      View in: PubMed
    6. Lanier CM, McTyre E, LeCompte M, Cramer CK, Hughes R, Watabe K, Lo HW, O'Neill S, Munley MT, Laxton AW, Tatter SB, Ruiz J, Chan MD. The number of prior lines of systemic therapy as a prognostic factor for patients with brain metastases treated with stereotactic radiosurgery: Results of a large single institution retrospective analysis. Clin Neurol Neurosurg. 2018 02; 165:24-28. PMID: 29289917.
      View in: PubMed
    7. LeCompte MC, McTyre E, Henson A, Farris M, Okoukoni C, Cramer CK, Triozzi P, Ruiz J, Watabe K, Lo HW, Munley MT, Laxton AW, Tatter SB, Zhou X, Chan M. Survival and Failure Outcomes Predicted by Brain Metastasis Volumetric Kinetics in Melanoma Patients Following Upfront Treatment with Stereotactic Radiosurgery Alone. Cureus. 2017 Dec 11; 9(12):e1934. PMID: 29464141.
      View in: PubMed
    8. Alphonse-Sullivan N, Taksler GB, Lycan T, Weaver KE, McTyre ER, Shenker RF, Page BR, Isom S, Johnson A, Munley MT, Laxton AW, Tatter SB, Watabe K, Chan MD, Ruiz J. Sociodemographic predictors of patients with brain metastases treated with stereotactic radiosurgery. Oncotarget. 2017 Nov 24; 8(60):101005-101011. PMID: 29254141.
      View in: PubMed
    9. McTyre E, Helis CA, Farris M, Wilkins L, Sloan D, Hinson WH, Bourland JD, Dezarn WA, Munley MT, Watabe K, Xing F, Laxton AW, Tatter SB, Chan MD. Emerging Indications for Fractionated Gamma Knife Radiosurgery. Neurosurgery. 2017 02 01; 80(2):210-216. PMID: 28536486.
      View in: PubMed
    10. Okoukoni C, Randolph DM, McTyre ER, Kwok A, Weaver AA, Blackstock AW, Munley MT, Willey JS. Early dose-dependent cortical thinning of the femoral neck in anal cancer patients treated with pelvic radiation therapy. Bone. 2017 01; 94:84-89. PMID: 27780791.
      View in: PubMed
    11. Willey JS, Kwok AT, Moore JE, Payne V, Lindburg CA, Balk SA, Olson J, Black PJ, Walb MC, Yammani RR, Munley MT. Spaceflight-Relevant Challenges of Radiation and/or Reduced Weight Bearing Cause Arthritic Responses in Knee Articular Cartilage. Radiat Res. 2016 Oct; 186(4):333-344. PMID: 27602483.
      View in: PubMed
    12. McKay WH, McTyre ER, Okoukoni C, Alphonse-Sullivan NK, Ruiz J, Munley MT, Qasem S, Lo HW, Xing F, Laxton AW, Tatter SB, Watabe K, Chan MD. Repeat stereotactic radiosurgery as salvage therapy for locally recurrent brain metastases previously treated with radiosurgery. J Neurosurg. 2017 Jul; 127(1):148-156. PMID: 27494815.
      View in: PubMed
    13. Okoukoni C, Lynch SK, McTyre ER, Randolph DM, Weaver AA, Blackstock AW, Lally BE, Munley MT, Willey JS. A cortical thickness and radiation dose mapping approach identifies early thinning of ribs after stereotactic body radiation therapy. Radiother Oncol. 2016 06; 119(3):449-53. PMID: 27072937.
      View in: PubMed
    14. Able CM, Baydush AH, Nguyen C, Gersh J, Ndlovu A, Rebo I, Booth J, Perez M, Sintay B, Munley MT. A model for preemptive maintenance of medical linear accelerators-predictive maintenance. Radiat Oncol. 2016 Mar 10; 11:36. PMID: 26965519.
      View in: PubMed
    15. Kilburn JM, Lucas JT, Soike MH, Ayala-Peacock DN, Blackstock AW, Hinson WH, Munley MT, Petty WJ, Urbanic JJ. Is a Clinical Target Volume (CTV) Necessary in the Treatment of Lung Cancer in the Modern Era Combining 4-D Imaging and Image-guided Radiotherapy (IGRT)? Cureus. 2016 Jan 23; 8(1):e466. PMID: 26929893.
      View in: PubMed
    16. Kilburn JM, Soike MH, Lucas JT, Ayala-Peacock D, Blackstock W, Isom S, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ. Image guided radiation therapy may result in improved local control in locally advanced lung cancer patients. Pract Radiat Oncol. 2016 May-Jun; 6(3):e73-e80. PMID: 26725964.
      View in: PubMed
    17. Walb MC, Black PJ, Payne VS, Munley MT, Willey JS. A reproducible radiation delivery method for unanesthetized rodents during periods of hind limb unloading. Life Sci Space Res (Amst). 2015 Jul; 6:10-4. PMID: 26097807.
      View in: PubMed
    18. Black PJ, Page BR, Lucas JT, Hughes RT, Laxton AW, Tatter SB, Munley MT, Chan MD. Factors that determine local control with gamma knife radiosurgery: The role of primary histology. J Radiosurg SBRT. 2015; 3(4):281-286. PMID: 26478823.
      View in: PubMed
    19. Wheeler KT, Payne V, D'Agostino RB, Walb MC, Munley MT, Metheny-Barlow LJ, Robbins ME. Impact of breathing 100% oxygen on radiation-induced cognitive impairment. Radiat Res. 2014 Nov; 182(5):580-5. PMID: 25338095.
      View in: PubMed
    20. Hutchinson ID, Olson J, Lindburg CA, Payne V, Collins B, Smith TL, Munley MT, Wheeler KT, Willey JS. Total-body irradiation produces late degenerative joint damage in rats. Int J Radiat Biol. 2014 Sep; 90(9):821-30. PMID: 24885745.
      View in: PubMed
    21. Kilburn JM, Lester SC, Lucas JT, Soike MH, Blackstock AW, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ. Management of mediastinal relapse after treatment with stereotactic body radiotherapy or accelerated hypofractionated radiotherapy for stage I/II non-small-cell lung cancer. J Thorac Oncol. 2014 Apr; 9(4):572-6. PMID: 24736084.
      View in: PubMed
    22. Kilburn JM, Ellis TL, Lovato JF, Urbanic JJ, Bourland JD, Daniel Bourland J, Munley MT, Deguzman AF, McMullen KP, Shaw EG, Tatter SB, Chan MD. Local control and toxicity outcomes in brainstem metastases treated with single fraction radiosurgery: is there a volume threshold for toxicity? J Neurooncol. 2014 Mar; 117(1):167-74. PMID: 24504497.
      View in: PubMed
    23. Kilburn JM, Kuremsky JG, Blackstock AW, Munley MT, Kearns WT, Hinson WH, Lovato JF, Miller AA, Petty WJ, Urbanic JJ. Thoracic re-irradiation using stereotactic body radiotherapy (SBRT) techniques as first or second course of treatment. Radiother Oncol. 2014 Mar; 110(3):505-10. PMID: 24444530.
      View in: PubMed
    24. Weller M, Marshall K, Lovato JF, Bourland JD, deGuzman AF, Munley MT, Shaw EG, Tatter SB, Chan MD. Single-institution retrospective series of gamma knife radiosurgery in the treatment of multiple sclerosis-related trigeminal neuralgia: factors that predict efficacy. Stereotact Funct Neurosurg. 2014; 92(1):53-8. PMID: 24217153.
      View in: PubMed
    25. Munley MT, Kagadis GC, McGee KP, Kirov AS, Jang S, Mutic S, Jeraj R, Xing L, Bourland JD. An introduction to molecular imaging in radiation oncology: a report by the AAPM Working Group on Molecular Imaging in Radiation Oncology (WGMIR). Med Phys. 2013 Oct; 40(10):101501. PMID: 24089890.
      View in: PubMed
    26. Almeida C, Nagarajan D, Tian J, Leal SW, Wheeler K, Munley M, Blackstock W, Zhao W. The role of alveolar epithelium in radiation-induced lung injury. PLoS One. 2013; 8(1):e53628. PMID: 23326473.
      View in: PubMed
    27. Miller MS, Moore JE, Walb MC, Kock ND, Attia A, Isom S, McBride JE, Munley MT. Chemoprevention by N-acetylcysteine of low-dose CT-induced murine lung tumorigenesis. Carcinogenesis. 2013 Feb; 34(2):319-24. PMID: 23104176.
      View in: PubMed
    28. Amponsah K, Ellis TL, Chan MD, Lovato JF, Bourland JD, deGuzman AF, Ekstrand KE, Munley MT, McMullen KP, Shaw EG, Tatter SB. Retrospective analysis of imaging techniques for treatment planning and monitoring of obliteration for gamma knife treatment of cerebral arteriovenous malformation. Neurosurgery. 2012 Oct; 71(4):893-9. PMID: 22791027.
      View in: PubMed
    29. Olson JD, Walb MC, Moore JE, Attia A, Sawyer HL, McBride JE, Wheeler KT, Miller MS, Munley MT. A gated-7T MRI technique for tracking lung tumor development and progression in mice after exposure to low doses of ionizing radiation. Radiat Res. 2012 Oct; 178(4):321-7. PMID: 22950352.
      View in: PubMed
    30. Munley MT. Targeted Molecular Imaging. Med Phys. 2012 Aug; 39(8):5302-5303. PMID: 28525150.
      View in: PubMed
    31. Loganathan AG, Chan MD, Alphonse N, Peiffer AM, Johnson AJ, McMullen KP, Urbanic JJ, Saconn PA, Bourland JD, Munley MT, Shaw EG, Tatter SB, Ellis TL. Clinical outcomes of brain metastases treated with Gamma Knife radiosurgery with 3.0?T versus 1.5?T MRI-based treatment planning: have we finally optimised detection of occult brain metastases? J Med Imaging Radiat Oncol. 2012 Oct; 56(5):554-60. PMID: 23043576.
      View in: PubMed
    32. Squire SE, Chan MD, Furr RM, Lowell DA, Tatter SB, Ellis TL, Bourland JD, Deguzman AF, Munley MT, Ekstrand KE, Shaw EG, McMullen KP. Gamma knife radiosurgery in the treatment of tumor-related facial pain. Stereotact Funct Neurosurg. 2012; 90(3):145-50. PMID: 22508112.
      View in: PubMed
    33. Marshall K, Chan MD, McCoy TP, Aubuchon AC, Bourland JD, McMullen KP, deGuzman AF, Munley MT, Shaw EG, Tatter SB, Ellis TL. Predictive variables for the successful treatment of trigeminal neuralgia with gamma knife radiosurgery. Neurosurgery. 2012 Mar; 70(3):566-72; discussion 572-3. PMID: 21849918.
      View in: PubMed
    34. Attia A, Chan MD, Mott RT, Russell GB, Seif D, Daniel Bourland J, Deguzman AF, Ellis TL, McMullen KP, Munley MT, Tatter SB, Shaw EG. Patterns of failure after treatment of atypical meningioma with gamma knife radiosurgery. J Neurooncol. 2012 May; 108(1):179-85. PMID: 22359231.
      View in: PubMed
    35. Harris S, Chan MD, Lovato JF, Ellis TL, Tatter SB, Bourland JD, Munley MT, deGuzman AF, Shaw EG, Urbanic JJ, McMullen KP. Gamma knife stereotactic radiosurgery as salvage therapy after failure of whole-brain radiotherapy in patients with small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):e53-9. PMID: 22342297.
      View in: PubMed
    36. Walb MC, Moore JE, Attia A, Wheeler KT, Miller MS, Munley MT. A technique for murine irradiation in a controlled gas environment. Biomed Sci Instrum. 2012; 48:470-7. PMID: 22846321.
      View in: PubMed
    37. Able CM, Hampton CJ, Baydush AH, Munley MT. Initial investigation using statistical process control for quality control of accelerator beam steering. Radiat Oncol. 2011 Dec 28; 6:180. PMID: 22204566.
      View in: PubMed
    38. Munley MT, Moore JE, Walb MC, Isom SP, Olson JD, Zora JG, Kock ND, Wheeler KT, Miller MS. Cancer-prone mice expressing the Ki-rasG12C gene show increased lung carcinogenesis after CT screening exposures. Radiat Res. 2011 Dec; 176(6):842-8. PMID: 21962004.
      View in: PubMed
    39. Lowell D, Tatter SB, Bourland JD, deGuzman AF, Ekstrand KE, Ellis TL, Lovato JF, McMullen KP, Munley MT, Shaw EG, Urbanic JJ, Chan MD. Toxicity of gamma knife radiosurgery in the treatment of intracranial tumors in patients with collagen vascular diseases or multiple sclerosis. Int J Radiat Oncol Biol Phys. 2011 Nov 15; 81(4):e519-24. PMID: 21601376.
      View in: PubMed
    40. Jensen CA, Chan MD, McCoy TP, Bourland JD, deGuzman AF, Ellis TL, Ekstrand KE, McMullen KP, Munley MT, Shaw EG, Urbanic JJ, Tatter SB. Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasis. J Neurosurg. 2011 Jun; 114(6):1585-91. PMID: 21166567.
      View in: PubMed
    41. Aubuchon AC, Chan MD, Lovato JF, Balamucki CJ, Ellis TL, Tatter SB, McMullen KP, Munley MT, Deguzman AF, Ekstrand KE, Bourland JD, Shaw EG. Repeat gamma knife radiosurgery for trigeminal neuralgia. Int J Radiat Oncol Biol Phys. 2011 Nov 15; 81(4):1059-65. PMID: 20932665.
      View in: PubMed
    42. Saconn PA, Shaw EG, Chan MD, Squire SE, Johnson AJ, McMullen KP, Tatter SB, Ellis TL, Lovato J, Bourland JD, Ekstrand KE, DeGuzman AF, Munley MT. Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: a single-institution retrospective review. Int J Radiat Oncol Biol Phys. 2010 Nov 15; 78(4):1142-6. PMID: 20832185.
      View in: PubMed
    43. Gersh JA, Wiant DB, Best RC, Bennett MC, Munley MT, King JD, McKee MM, Baydush AH. Improved volumetric imaging in tomosynthesis using combined multiaxial sweeps. J Appl Clin Med Phys. 2010 Sep 03; 11(4):3331. PMID: 21081893.
      View in: PubMed
    44. Wentworth S, Pinn M, Bourland JD, Deguzman AF, Ekstrand K, Ellis TL, Glazier SS, McMullen KP, Munley M, Stieber VW, Tatter SB, Shaw EG. Clinical experience with radiation therapy in the management of neurofibromatosis-associated central nervous system tumors. Int J Radiat Oncol Biol Phys. 2009 Jan 01; 73(1):208-13. PMID: 18687535.
      View in: PubMed
    45. Socinski MA, Blackstock AW, Bogart JA, Wang X, Munley M, Rosenman J, Gu L, Masters GA, Ungaro P, Sleeper A, Green M, Miller AA, Vokes EE. Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105. J Clin Oncol. 2008 May 20; 26(15):2457-63. PMID: 18487565.
      View in: PubMed
    46. Stieber V, Robbins M, Balamucki C, deGuzman A, Tatter S, Ekstrand K, McMullen K, Branch C, Shaw E, Bourland JD, Lovato J, Munley M, Ellis T. Determination of a clinical value for the repair half-time (T1/2) of the trigeminal nerve based on outcome data from gamma knife radiosurgery for facial pain. Radiat Res. 2007 Aug; 168(2):143-8. PMID: 17638402.
      View in: PubMed
    47. Balamucki CJ, Stieber VW, Ellis TL, Tatter SB, Deguzman AF, McMullen KP, Lovato J, Shaw EG, Ekstrand KE, Bourland JD, Munley MT, Robbins M, Branch C. Does dose rate affect efficacy? The outcomes of 256 gamma knife surgery procedures for trigeminal neuralgia and other types of facial pain as they relate to the half-life of cobalt. J Neurosurg. 2006 Nov; 105(5):730-5. PMID: 17121135.
      View in: PubMed
    48. Dixon RL, Munley MT, Bayram E. An improved analytical model for CT dose simulation with a new look at the theory of CT dose. Med Phys. 2005 Dec; 32(12):3712-28. PMID: 16475771.
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    49. Anscher MS, Marks LB, Shafman TD, Clough R, Huang H, Tisch A, Munley M, Herndon JE, Garst J, Crawford J, Jirtle RL. Risk of long-term complications after TFG-beta1-guided very-high-dose thoracic radiotherapy. Int J Radiat Oncol Biol Phys. 2003 Jul 15; 56(4):988-95. PMID: 12829134.
      View in: PubMed
    50. Lind PA, Marks LB, Hollis D, Fan M, Zhou SM, Munley MT, Shafman TD, Jaszczak RJ, Coleman RE. Receiver operating characteristic curves to assess predictors of radiation-induced symptomatic lung injury. Int J Radiat Oncol Biol Phys. 2002 Oct 01; 54(2):340-7. PMID: 12243806.
      View in: PubMed
    51. Woel RT, Munley MT, Hollis D, Fan M, Bentel G, Anscher MS, Shafman T, Coleman RE, Jaszczak RJ, Marks LB. The time course of radiation therapy-induced reductions in regional perfusion: a prospective study with >5 years of follow-up. Int J Radiat Oncol Biol Phys. 2002 Jan 01; 52(1):58-67. PMID: 11777622.
      View in: PubMed
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