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Clinical and Translational Science Institute

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Last Name

Kiran Kumar Solingapuram Sai, Ph.D.

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentPet Center
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Solingapuram Sai KK, Bashetti N, Chen X, Norman S, Hines JW, Meka O, Kumar JVS, Devanathan S, Deep G, Furdui CM, Mintz A. Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer. EJNMMI Res. 2019 May 17; 9(1):43. PMID: 31101996.
      View in: PubMed
    2. Prabhakaran J, Sai KKS, Sattiraju A, Mintz A, Mann JJ, Kumar JSD. Radiosynthesis and evaluation of [11C]CMP, a high affinity GSK3 ligand. Bioorg Med Chem Lett. 2019 Mar 15; 29(6):778-781. PMID: 30709652.
      View in: PubMed
    3. Pandya DN, Bhatt NB, Almaguel F, Rideout-Danner S, Gage HD, Solingapuram Sai KK, Wadas TJ. 89Zr-Chloride Can Be Used for Immuno-PET Radiochemistry Without Loss of Antigen Reactivity In Vivo. J Nucl Med. 2019 May; 60(5):696-701. PMID: 30442753.
      View in: PubMed
    4. Solingapuram Sai KK, Prabhakaran J, Ramanathan G, Rideout S, Whitlow C, Mintz A, Mann JJ, Kumar JSD. Radiosynthesis and Evaluation of [11C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules. ACS Med Chem Lett. 2018 May 10; 9(5):452-456. PMID: 29795758.
      View in: PubMed
    5. Prudner BC, Sun F, Kremer JC, Xu J, Huang C, Sai KKS, Morgan Z, Leeds H, McConathy J, Van Tine BA. Amino Acid Uptake Measured by [18F]AFETP Increases in Response to Arginine Starvation in ASS1-Deficient Sarcomas. Theranostics. 2018; 8(8):2107-2116. PMID: 29721066.
      View in: PubMed
    6. Kumar JSD, Solingapuram Sai KK, Prabhakaran J, Oufkir HR, Ramanathan G, Whitlow CT, Dileep H, Mintz A, Mann JJ. Radiosynthesis and in Vivo Evaluation of [11C]MPC-6827, the First Brain Penetrant Microtubule PET Ligand. J Med Chem. 2018 03 08; 61(5):2118-2123. PMID: 29457976.
      View in: PubMed
    7. John WS, Martin TJ, Solingapuram Sai KK, Nader SH, Gage HD, Mintz A, Nader MA. Chronic ?9-THC in Rhesus Monkeys: Effects on Cognitive Performance and Dopamine D2/D3 Receptor Availability. J Pharmacol Exp Ther. 2018 02; 364(2):300-310. PMID: 29203575.
      View in: PubMed
    8. Solingapuram Sai KK, Donald Gage H, Almaguel F, Neth B, Hughes TM, Tremblay S, Castellano CA, Cunnane SC, Jorgensen MJ, Craft S, Mintz A. Automated synthesis of 1-[11C]acetoacetate on a TRASIS AIO module. Appl Radiat Isot. 2017 Nov; 129:57-61. PMID: 28806598.
      View in: PubMed
    9. Sattiraju A, Solingapuram Sai KK, Xuan A, Pandya DN, Almaguel FG, Wadas TJ, Herpai DM, Debinski W, Mintz A. IL13RA2 targeted alpha particle therapy against glioblastomas. Oncotarget. 2017 Jun 27; 8(26):42997-43007. PMID: 28562337.
      View in: PubMed
    10. Sattiraju A, Xiong X, Pandya DN, Wadas TJ, Xuan A, Sun Y, Jung Y, Sai KKS, Dorsey JF, Li KC, Mintz A. Alpha Particle Enhanced Blood Brain/Tumor Barrier Permeabilization in Glioblastomas Using Integrin Alpha-v Beta-3-Targeted Liposomes. Mol Cancer Ther. 2017 10; 16(10):2191-2200. PMID: 28619756.
      View in: PubMed
    11. Prabhakaran J, Zanderigo F, Sai KKS, Rubin-Falcone H, Jorgensen MJ, Kaplan JR, Mintz A, Mann JJ, Kumar JSD. Radiosynthesis and in Vivo Evaluation of [11C]A1070722, a High Affinity GSK-3 PET Tracer in Primate Brain. ACS Chem Neurosci. 2017 08 16; 8(8):1697-1703. PMID: 28485573.
      View in: PubMed
    12. Sai KKS, Zachar Z, Bingham PM, Mintz A. Metabolic PET Imaging in Oncology. AJR Am J Roentgenol. 2017 Aug; 209(2):270-276. PMID: 28463521.
      View in: PubMed
    13. Solingapuram Sai KK, Prabhakaran J, Sattiraju A, Mann JJ, Mintz A, Kumar JSD. Radiosynthesis and evaluation of IGF1R PET ligand [11C]GSK1838705A. Bioorg Med Chem Lett. 2017 07 01; 27(13):2895-2897. PMID: 28479199.
      View in: PubMed
    14. Sai KKS, Sattiraju A, Almaguel FG, Xuan A, Rideout S, Krishnaswamy RS, Zhang J, Herpai DM, Debinski W, Mintz A. Peptide-based PET imaging of the tumor restricted IL13RA2 biomarker. Oncotarget. 2017 Aug 01; 8(31):50997-51007. PMID: 28881623.
      View in: PubMed
    15. Solingapuram Sai KK, Das BC, Sattiraju A, Almaguel FG, Craft S, Mintz A. Radiolabeling and initial biological evaluation of [18F]KBM-1 for imaging RAR-a receptors in neuroblastoma. Bioorg Med Chem Lett. 2017 03 15; 27(6):1425-1427. PMID: 28216044.
      View in: PubMed
    16. Sattiraju A, Sai KKS, Mintz A. Glioblastoma Stem Cells and Their Microenvironment. Adv Exp Med Biol. 2017; 1041:119-140. PMID: 29204831.
      View in: PubMed
    17. Prabhakaran J, Solingapuram Sai KK, Zanderigo F, Rubin-Falcone H, Jorgensen MJ, Kaplan JR, Tooke KI, Mintz A, Mann JJ, Kumar JSD. In vivo evaluation of [18F]FECIMBI-36, an agonist 5-HT2A/2C receptor PET radioligand in nonhuman primate. Bioorg Med Chem Lett. 2017 01 01; 27(1):21-23. PMID: 27889455.
      View in: PubMed
    18. Birbrair A, Sattiraju A, Zhu D, Zulato G, Batista I, Nguyen VT, Messi ML, Solingapuram Sai KK, Marini FC, Delbono O, Mintz A. Novel Peripherally Derived Neural-Like Stem Cells as Therapeutic Carriers for Treating Glioblastomas. Stem Cells Transl Med. 2017 02; 6(2):471-481. PMID: 28191774.
      View in: PubMed
    19. Kiran Kumar Solingapuram Sai *, Don Gage , Mike Nader, Robert H. Mach , Akiva Mintz . Improved Automated Radiosynthesis of [11C]PBR28. Sci. Pharm. 2015; (83):413-427.
    20. Solingapuram Sai KK, Gage D, Nader M, Mach RH, Mintz A. Improved Automated Radiosynthesis of [(11)C]PBR28. Sci Pharm. 2015 Jul-Sep; 83(3):413-27. PMID: 26839827.
      View in: PubMed
    21. Wadas TJ, Pandya DN, Solingapuram Sai KK, Mintz A. Molecular targeted a-particle therapy for oncologic applications. AJR Am J Roentgenol. 2014 Aug; 203(2):253-60. PMID: 25055256.
      View in: PubMed
    22. Sai KK, Fan J, Tu Z, Zerkel P, Mach RH, Kharasch ED. Automated radiochemical synthesis and biodistribution of [¹¹C]l-a-acetylmethadol ([¹¹C]LAAM). Appl Radiat Isot. 2014 Sep; 91:135-40. PMID: 24935116.
      View in: PubMed
    23. Sai KK, Huang C, Yuan L, Zhou D, Piwnica-Worms D, Garbow JR, Engelbach JA, Mach RH, Rich KM, McConathy J. 18F-AFETP, 18F-FET, and 18F-FDG imaging of mouse DBT gliomas. J Nucl Med. 2013 Jul; 54(7):1120-6. PMID: 23650628.
      View in: PubMed
    24. Sai KK, Jones LA, Mach RH. Development of (18)F-labeled PET probes for imaging cell proliferation. Curr Top Med Chem. 2013; 13(8):892-908. PMID: 23590172.
      View in: PubMed
    25. Solingapuram Sai KK, Kil KE, Tu Z, Chu W, Finck BN, Rothfuss JM, Shoghi KI, Welch MJ, Gropler RJ, Mach RH. Synthesis, radiolabeling and initial in vivo evaluation of [(11)C]KSM-01 for imaging PPAR-a receptors. Bioorg Med Chem Lett. 2012 Oct 01; 22(19):6233-6. PMID: 22939697.
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    26. Sai KK, O'Connor MJ, Klumpp DA. Aza-Nazarov cyclization cascades. Tetrahedron Lett. 2011 Apr 27; 52(17):2195-2198. PMID: 21660198.
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    27. Sai KK, Tokarz MJ, Malunchuk AP, Zheng C, Gilbert TM, Klumpp DA. N-heterocyclic superelectrophiles and evidence for single electron transfer chemistry. J Am Chem Soc. 2008 Nov 05; 130(44):14388-9. PMID: 18841889.
      View in: PubMed
    28. Sai KK, Esteves PM, da Penha ET, Klumpp DA. Superacid-promoted reactions of alpha-ketoamides and related systems. J Org Chem. 2008 Sep 05; 73(17):6506-12. PMID: 18665649.
      View in: PubMed
    29. Sai KK, Gilbert TM, Klumpp DA. Knorr cyclizations and distonic superelectrophiles. J Org Chem. 2007 Dec 07; 72(25):9761-4. PMID: 17999519.
      View in: PubMed
    30. Zhang Y, DeSchepper DJ, Gilbert TM, Sai KK, Klumpp DA. Superacid promoted reactions of N-acyliminium salts and evidence for the involvement of superelectrophiles. Chem Commun (Camb). 2007 Oct 21; (39):4032-4. PMID: 17912406.
      View in: PubMed
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