Loading...
Explore More at wakehealth.edu

Clinical and Translational Science Institute

Keywords
Last Name

Jeffrey L. Weiner, Ph.D.

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentPhysiology and Pharmacology
Address
vCardDownload vCard
    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentInstitute for Regenerative Medicine


    Collapse Research 
    Collapse research activities and funding
    F32AA005425     (WEINER, JEFFREY L.)Dec 1, 1995
    NIH/NIAAA
    ETHANOL MODULATION OF GABAA RECEPTOR FUNCTION
    Role: Principal Investigator

    R29AA012251     (WEINER, JEFFREY L.)Sep 18, 1998 - Aug 31, 2003
    NIH/NIAAA
    ETHANOL AND SYNAPTIC GABAA RECEPTORS
    Role: Principal Investigator

    R01AA012251     (WEINER, JEFFREY L.)Sep 18, 1998 - Aug 31, 2004
    NIH/NIAAA
    ETHANOL AND SYNAPTIC GABAA RECEPTORS
    Role: Principal Investigator

    R01AA013960     (WEINER, JEFFREY L.)Jul 1, 2003 - Jun 30, 2009
    NIH/NIAAA
    Ethanol and Presynaptic GABA beta Receptor Function
    Role: Principal Investigator

    R21AA016643     (WEINER, JEFFREY L.)Jul 15, 2007 - Jun 30, 2010
    NIH/NIAAA
    Synaptic Correlates of Ethanol-Related Behaviors
    Role: Principal Investigator

    R37AA017531     (WEINER, JEFFREY L)Apr 1, 2008 - Apr 30, 2019
    NIH/NIAAA
    Synaptic Correlates of Vulnerability and Resilience to Alcohol Use Disorders
    Role: Principal Investigator

    P01AA017056     (WEINER, JEFFREY L)Jul 1, 2008 - Oct 31, 2012
    NIH/NIAAA
    Translational Centerfor the Neurobehaviral Study of Alcohol
    Role: Principal Investigator

    R01AA017531     (WEINER, JEFFREY L)May 1, 2009 - Apr 30, 2014
    NIH/NIAAA
    Synaptic Correlates of Ethanol-Mediated Anxiolysis
    Role: Principal Investigator

    P01AA021099     (WEINER, JEFFREY L)Sep 20, 2012 - Aug 31, 2017
    NIH/NIAAA
    Translational Studies on Early-life Stress and Vulnerability to Alcohol Addiction
    Role: Principal Investigator

    R13AA024639     (WEINER, JEFFREY L)Nov 1, 2015 - Oct 31, 2017
    NIH/NIAAA
    2016 and 2018 Alcohol and the Nervous System GRC
    Role: Principal Investigator

    R01AA026551     (WEINER, JEFFREY L)Sep 15, 2017 - Jun 30, 2022
    NIH/NIAAA
    Neural Substrates of Comorbid Alcohol Use Disorder and Post-Traumatic Stress Disorder
    Role: Principal Investigator

    P50AA026117     (WEINER, JEFFREY L)Dec 10, 2017 - Nov 30, 2022
    NIH/NIAAA
    Wake Forest Translational Alcohol Research Center (WF-TARC)
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Deal AL, Konstantopoulos JK, Weiner JL, Budygin EA. Exploring the consequences of social defeat stress and intermittent ethanol drinking on dopamine dynamics in the rat nucleus accumbens. Sci Rep. 2018 01 10; 8(1):332. PMID: 29321525.
      View in: PubMed
    2. Almonte AG, Ewin SE, Mauterer MI, Morgan JW, Carter ES, Weiner JL. Enhanced ventral hippocampal synaptic transmission and impaired synaptic plasticity in a rodent model of alcohol addiction vulnerability. Sci Rep. 2017 Sep 26; 7(1):12300. PMID: 28951619.
      View in: PubMed
    3. Mikhailova MA, Bass CE, Grinevich VP, Chappell AM, Deal AL, Bonin KD, Weiner JL, Gainetdinov RR, Budygin EA. Optogenetically-induced tonic dopamine release from VTA-nucleus accumbens projections inhibits reward consummatory behaviors. Neuroscience. 2016 10 01; 333:54-64. PMID: 27421228.
      View in: PubMed
    4. Butler TR, Karkhanis AN, Jones SR, Weiner JL. Adolescent Social Isolation as a Model of Heightened Vulnerability to Comorbid Alcoholism and Anxiety Disorders. Alcohol Clin Exp Res. 2016 06; 40(6):1202-14. PMID: 27154240.
      View in: PubMed
    5. Karkhanis AN, Rose JH, Weiner JL, Jones SR. Early-Life Social Isolation Stress Increases Kappa Opioid Receptor Responsiveness and Downregulates the Dopamine System. Neuropsychopharmacology. 2016 08; 41(9):2263-74. PMID: 26860203.
      View in: PubMed
    6. Yorgason JT, Calipari ES, Ferris MJ, Karkhanis AN, Fordahl SC, Weiner JL, Jones SR. Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum. Neuropharmacology. 2016 Feb; 101:471-9. PMID: 26525189.
      View in: PubMed
    7. Adamah-Biassi EB, Almonte AG, Blagovechtchenski E, Grinevich VP, Weiner JL, Bonin KD, Budygin EA. Real time adenosine fluctuations detected with fast-scan cyclic voltammetry in the rat striatum and motor cortex. J Neurosci Methods. 2015 Dec 30; 256:56-62. PMID: 26310181.
      View in: PubMed
    8. Rau AR, Chappell AM, Butler TR, Ariwodola OJ, Weiner JL. Increased Basolateral Amygdala Pyramidal Cell Excitability May Contribute to the Anxiogenic Phenotype Induced by Chronic Early-Life Stress. J Neurosci. 2015 Jul 01; 35(26):9730-40. PMID: 26134655; PMCID: PMC4571506.
    9. Karkhanis AN, Alexander NJ, McCool BA, Weiner JL, Jones SR. Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala. Synapse. 2015 Aug; 69(8):385-95. PMID: 25963724; PMCID: PMC4578716.
    10. Helms CM, Bell RL, Bennett AJ, Davies DL, Chester JA, Kosten TA, Leeman RF, Panicker S, Platt DM, Weiner JL, Edwards S. The importance of animals in advancing research on alcohol use disorders. Alcohol Clin Exp Res. 2015 Apr; 39(4):575-8. PMID: 25833015.
      View in: PubMed
    11. Rau AR, Ariwodola OJ, Weiner JL. Postsynaptic adenosine A2A receptors modulate intrinsic excitability of pyramidal cells in the rat basolateral amygdala. Int J Neuropsychopharmacol. 2015 Feb 25; 18(6). PMID: 25716780; PMCID: PMC4438553.
    12. Karkhanis AN, Locke JL, McCool BA, Weiner JL, Jones SR. Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood. Alcohol Clin Exp Res. 2014 Nov; 38(11):2770-9. PMID: 25421514; PMCID: PMC4519347.
    13. Butler TR, Carter E, Weiner JL. Adolescent social isolation does not lead to persistent increases in anxiety- like behavior or ethanol intake in female long-evans rats. Alcohol Clin Exp Res. 2014 Aug; 38(8):2199-207. PMID: 25092210; PMCID: PMC4146661.
    14. Gill KE, Chappell AM, Beveridge TJ, Porrino LJ, Weiner JL. Chronic methylphenidate treatment during early life is associated with greater ethanol intake in socially isolated rats. Alcohol Clin Exp Res. 2014 Aug; 38(8):2260-8. PMID: 25156616; PMCID: PMC4145615.
    15. Skelly MJ, Weiner JL. Chronic treatment with prazosin or duloxetine lessens concurrent anxiety-like behavior and alcohol intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use. Brain Behav. 2014 Jul; 4(4):468-83. PMID: 25161814; PMCID: PMC4128029.
    16. Butler TR, Ariwodola OJ, Weiner JL. The impact of social isolation on HPA axis function, anxiety-like behaviors, and ethanol drinking. Front Integr Neurosci. 2014; 7:102. PMID: 24427122; PMCID: PMC3877772.
    17. Bass CE, Grinevich VP, Gioia D, Day-Brown JD, Bonin KD, Stuber GD, Weiner JL, Budygin EA. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Front Behav Neurosci. 2013; 7:173. PMID: 24324415; PMCID: PMC3840465.
    18. Rau AR, Ariwodola OJ, Weiner JL. Presynaptic adenosine A1 receptors modulate excitatory transmission in the rat basolateral amygdala. Neuropharmacology. 2014 Feb; 77:465-74. PMID: 24212058; PMCID: PMC3872110.
    19. Abrahao KP, Ariwodola OJ, Butler TR, Rau AR, Skelly MJ, Carter E, Alexander NP, McCool BA, Souza-Formigoni ML, Weiner JL. Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration. J Neurosci. 2013 Mar 13; 33(11):4834-42. PMID: 23486954; PMCID: PMC3658831.
    20. Yorgason JT, España RA, Konstantopoulos JK, Weiner JL, Jones SR. Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats. Eur J Neurosci. 2013 Mar; 37(6):1022-31. PMID: 23294165; PMCID: PMC3746484.
    21. Chappell AM, Carter E, McCool BA, Weiner JL. Adolescent rearing conditions influence the relationship between initial anxiety-like behavior and ethanol drinking in male Long Evans rats. Alcohol Clin Exp Res. 2013 Jan; 37 Suppl 1:E394-403. PMID: 22924742; PMCID: PMC3529208.
    22. Silberman Y, Ariwodola OJ, Weiner JL. ß1-adrenoceptor activation is required for ethanol enhancement of lateral paracapsular GABAergic synapses in the rat basolateral amygdala. J Pharmacol Exp Ther. 2012 Nov; 343(2):451-9. PMID: 22904357; PMCID: PMC3477216.
    23. Molina DP, Ariwodola OJ, Weiner JL, Brunso-Bechtold JK, Adams MM. Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats. Age (Dordr). 2013 Oct; 35(5):1575-87. PMID: 22851280; PMCID: PMC3776110.
    24. Molina DP, Ariwodola OJ, Linville C, Sonntag WE, Weiner JL, Brunso-Bechtold JK, Adams MM. Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats. Neurobiol Aging. 2012 Sep; 33(9):1938-49. PMID: 22015312; PMCID: PMC3266474.
    25. Silberman Y, Ariwodola OJ, Chappell AM, Yorgason JT, Weiner JL. Lateral paracapsular GABAergic synapses in the basolateral amygdala contribute to the anxiolytic effects of beta 3 adrenoceptor activation. Neuropsychopharmacology. 2010 Aug; 35(9):1886-96. PMID: 20410872; PMCID: PMC3055643.
    26. Silberman Y, Bajo M, Chappell AM, Christian DT, Cruz M, Diaz MR, Kash T, Lack AK, Messing RO, Siggins GR, Winder D, Roberto M, McCool BA, Weiner JL. Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions. Alcohol. 2009 Nov; 43(7):509-19. PMID: 19913194; PMCID: PMC2814297.
    27. Silberman Y, Ariwodola OJ, Weiner JL. Differential effects of GABAB autoreceptor activation on ethanol potentiation of local and lateral paracapsular GABAergic synapses in the rat basolateral amygdala. Neuropharmacology. 2009 Apr; 56(5):886-95. PMID: 19371578; PMCID: PMC3449063.
    28. Chappell AM, Weiner JL. Relationship between ethanol's acute locomotor effects and ethanol self-administration in male Long-Evans rats. Alcohol Clin Exp Res. 2008 Dec; 32(12):2088-99. PMID: 18828804; PMCID: PMC2814303.
    29. Läck AK, Ariwodola OJ, Chappell AM, Weiner JL, McCool BA. Ethanol inhibition of kainate receptor-mediated excitatory neurotransmission in the rat basolateral nucleus of the amygdala. Neuropharmacology. 2008 Oct; 55(5):661-8. PMID: 18617194; PMCID: PMC2615485.
    30. Silberman Y, Shi L, Brunso-Bechtold JK, Weiner JL. Distinct mechanisms of ethanol potentiation of local and paracapsular GABAergic synapses in the rat basolateral amygdala. J Pharmacol Exp Ther. 2008 Jan; 324(1):251-60. PMID: 17921186.
      View in: PubMed
    31. Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. J Pharmacol Exp Ther. 2006 Oct; 319(1):219-27. PMID: 16785315.
      View in: PubMed
    32. DuBois DW, Perlegas A, Floyd DW, Weiner JL, McCool BA. Distinct functional characteristics of the lateral/basolateral amygdala GABAergic system in C57BL/6J and DBA/2J mice. J Pharmacol Exp Ther. 2006 Aug; 318(2):629-40. PMID: 16651400.
      View in: PubMed
    33. Crowder TL, Ariwodola OJ, Weiner JL. Kainate receptor activation potentiates GABAergic synaptic transmission in the nucleus accumbens core. Brain Res. 2006 May 09; 1088(1):73-82. PMID: 16626659.
      View in: PubMed
    34. Ramsey MM, Adams MM, Ariwodola OJ, Sonntag WE, Weiner JL. Functional characterization of des-IGF-1 action at excitatory synapses in the CA1 region of rat hippocampus. J Neurophysiol. 2005 Jul; 94(1):247-54. PMID: 15985695.
      View in: PubMed
    35. Ariwodola OJ, Weiner JL. Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors. J Neurosci. 2004 Nov 24; 24(47):10679-86. PMID: 15564584.
      View in: PubMed
    36. Carta M, Ariwodola OJ, Weiner JL, Valenzuela CF. Alcohol potently inhibits the kainate receptor-dependent excitatory drive of hippocampal interneurons. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6813-8. PMID: 12732711; PMCID: PMC164529.
    37. Hampson RE, Zhuang SY, Weiner JL, Deadwyler SA. Functional significance of cannabinoid-mediated, depolarization-induced suppression of inhibition (DSI) in the hippocampus. J Neurophysiol. 2003 Jul; 90(1):55-64. PMID: 12649318.
      View in: PubMed
    38. Crowder TL, Weiner JL. Functional characterization of kainate receptors in the rat nucleus accumbens core region. J Neurophysiol. 2002 Jul; 88(1):41-8. PMID: 12091531.
      View in: PubMed
    Weiner's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _