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Clinical and Translational Science Institute

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Last Name

Hariom Yadav

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentInternal Medicine - Molecular Medicine
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    Other Positions
    TitleAssistant Professor
    InstitutionWake Forest School of Medicine
    DepartmentMicrobiology and Immunology


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    Collapse Biography 
    Collapse education and training
    National Dairy Research Institute, Karnal, IndiaPhD12/2006Biochemistry
    Jiwaji University, Gwalior, IndiaM.Sc.06/2001Applied Biochemistry
    Jiwaji University, Gwalior, IndiaB.Sc.06/1999Biology

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Nagpal R, Wang S, Ahmadi S, Hayes J, Gagliano J, Subashchandrabose S, Kitzman DW, Becton T, Read R, Yadav H. Human-origin probiotic cocktail increases short-chain fatty acid production via modulation of mice and human gut microbiome. Sci Rep. 2018 Aug 23; 8(1):12649. PMID: 30139941.
      View in: PubMed
    2. Wankhade UD, Lee JH, Dagur PK, Yadav H, Shen M, Chen W, Kulkarni AB, McCoy JP, Finkel T, Cypess AM, Rane SG. TGF-ß receptor 1 regulates progenitors that promote browning of white fat. Mol Metab. 2018 Oct; 16:160-171. PMID: 30100246.
      View in: PubMed
    3. Nagpal R, Mainali R, Ahmadi S, Wang S, Singh R, Kavanagh K, Kitzman DW, Kushugulova A, Marotta F, Yadav H. Gut microbiome and aging: Physiological and mechanistic insights. Nutr Healthy Aging. 2018 Jun 15; 4(4):267-285. PMID: 29951588.
      View in: PubMed
    4. Nagpal R, Shively CA, Appt SA, Register TC, Michalson KT, Vitolins MZ, Yadav H. Gut Microbiome Composition in Non-human Primates Consuming a Western or Mediterranean Diet. Front Nutr. 2018; 5:28. PMID: 29922651.
      View in: PubMed
    5. Nagpal R, Yadav H. Bacterial Translocation from the Gut to the Distant Organs: An Overview. Ann Nutr Metab. 2017; 71 Suppl 1:11-16. PMID: 28950279.
      View in: PubMed
    6. Khan Z, Khan AA, Yadav H, Prasad GBKS, Bisen PS. Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma. Cell Mol Biol Lett. 2017; 22:8. PMID: 28536639.
      View in: PubMed
    7. Kelley EE, Paes AM, Yadav H, Quijano C, Cassina A, Trostchansky A. Interplay between Oxidative Stress and Metabolism in Signalling and Disease 2016. Oxid Med Cell Longev. 2017; 2017:7013972. PMID: 28203320.
      View in: PubMed
    8. Yadav H, Devalaraja S, Chung ST, Rane SG. TGF-ß1/Smad3 Pathway Targets PP2A-AMPK-FoxO1 Signaling to Regulate Hepatic Gluconeogenesis. J Biol Chem. 2017 02 24; 292(8):3420-3432. PMID: 28069811.
      View in: PubMed
    9. Angmo S, Tripathi N, Abbat S, Sharma S, Singh SS, Halder A, Yadav K, Shukla G, Sandhir R, Rishi V, Bharatam PV, Yadav H, Singhal NK. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 01 05; 7:40097. PMID: 28054602.
      View in: PubMed
    10. Wankhade UD, Shen M, Yadav H, Thakali KM. Novel Browning Agents, Mechanisms, and Therapeutic Potentials of Brown Adipose Tissue. Biomed Res Int. 2016; 2016:2365609. PMID: 28105413.
      View in: PubMed
    11. Develaraja S, Reddy A, Yadav M, Jain S, Yadav H. Whole Grains in Amelioration of Metabolic Derangements. J Nutrit Health Food Sci. 2016; 4(4):1-11. PMID: 28944285.
      View in: PubMed
    12. Yadav H, Jain S, Nagpal R, Marotta F. Increased fecal viral content associated with obesity in mice. World J Diabetes. 2016 Aug 10; 7(15):316-20. PMID: 27555892; PMCID: PMC4980638.
    13. Trostchansky A, Quijano C, Yadav H, Kelley EE, Cassina AM. Interplay between Oxidative Stress and Metabolism in Signalling and Disease. Oxid Med Cell Longev. 2016; 2016:3274296. PMID: 26949446; PMCID: PMC4753690.
    14. Mukhija K, Singhal K, Angmo S, Yadav K, Yadav H, Sandhir R, Singhal NK. Potential of Alginate Encapsulated Ferric Saccharate Microemulsions to Ameliorate Iron Deficiency in Mice. Biol Trace Elem Res. 2016 Jul; 172(1):179-92. PMID: 26637994.
      View in: PubMed
    15. Yadav H, Rane SG. Dietary fatty acids: Friends or foes? Obesity (Silver Spring). 2015 Jul; 23(7):1329. PMID: 26110889.
      View in: PubMed
    16. Mishra V, Shah C, Mokashe N, Chavan R, Yadav H, Prajapati J. Probiotics as potential antioxidants: a systematic review. J Agric Food Chem. 2015 Apr 15; 63(14):3615-26. PMID: 25808285.
      View in: PubMed
    17. Nagpal R, Yadav H, Marotta F. Gut microbiota: the next-gen frontier in preventive and therapeutic medicine? Front Med (Lausanne). 2014; 1:15. PMID: 25767799; PMCID: PMC4341269.
    18. Yadav H, Lee JH, Lloyd J, Walter P, Rane SG. Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. J Biol Chem. 2013 Aug 30; 288(35):25088-97. PMID: 23836895; PMCID: PMC3757173.
    19. Marotta F, Lorenzetti A, Catanzaro R, Zerbinati N, Jain S, Solimene U, Yaduvanshi SK, Yadav H, Sapienza C, Srivastava N, Milazzo M, Italia A. A sturgeon-derived bioactive compound beneficially modulates nuclear receptors controlling metabolic functions in patients with metabolic syndrome. Acta Biomed. 2013 Jun 19; 84(1):53-60. PMID: 24189763.
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    20. Yadav J, Kumar A, Mahor P, Goel AK, Chaudhary HS, Yadava PK, Yadav H, Kumar P. Distribution of airborne microbes and antibiotic susceptibility pattern of bacteria during Gwalior trade fair, Central India. J Formos Med Assoc. 2015 Jul; 114(7):639-46. PMID: 23742901.
      View in: PubMed
    21. Yadav H, Jain S. Herbo-probiotic therapy in cardioprotection: a new way of nature to nurture. Nutrition. 2013 Jul-Aug; 29(7-8):1070-1. PMID: 23352466.
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    22. Pandey R, Kumar N, Yadav M, Nagpal R, Jain S, Yadav H. Anti-diabetic compounds and their patent information: an update. Recent Pat Inflamm Allergy Drug Discov. 2013 Jan 01; 7(1):35-48. PMID: 23016523.
      View in: PubMed
    23. Kumar M, Nagpal R, Hemalatha R, Verma V, Kumar A, Singh S, Marotta F, Jain S, Yadav H. Targeted cancer therapies: the future of cancer treatment. Acta Biomed. 2012 Dec; 83(3):220-33. PMID: 23762999.
      View in: PubMed
    24. Jain S, Marotta F, Catanzaro R, Yadav H. Immune system and gut flora interactions are important episodes in metabolic diseases. J Gastrointestin Liver Dis. 2012 Dec; 21(4):347-8. PMID: 23256115.
      View in: PubMed
    25. Takadanohara H, Catanzaro R, Chui de H, He F, Yadav H, Ganguli A, Sakata Y, Solimene U, Minelli E, Kobayashi R, Nagamachi Y, Marotta F. Beneficial effect of a symbiotic preparation with S. boulardii lysate in mild stress-induced gut hyper-permeability. Acta Biomed. 2012 Dec; 83(3):208-16. PMID: 23762997.
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    26. Yaduvanshi SK, Srivastava N, Prasad GB, Yadav M, Jain S, Yadav H. Genotoxic Potential of Reactive Oxygen Species (Ros), Lipid Peroxidation and DNA Repair Enzymes (Fpg and Endo III) in Alloxan Injected Diabetic Rats. Endocr Metab Immune Disord Drug Targets. 2012 Nov 28. PMID: 23210730.
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    27. Yaduvanshi SK, Srivastava N, Marotta F, Jain S, Yadav H. Evaluation of micronuclei induction capacity and mutagenicity of organochlorine and organophosphate pesticides. Drug Metab Lett. 2012 Sep 01; 6(3):187-97. PMID: 23092307.
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    28. Lorenzetti A, Marotta F, Yadav H, Celep G, Minelli E, Carrera-Bastos P, Jain S, Polimeni A, Solimene U. Improving sperm quality and spermatogenesis through a bioactive marine compound: an experimental study. Acta Biomed. 2012 Aug; 83(2):108-13. PMID: 23393918.
      View in: PubMed
    29. Catanzaro R, Lorenzetti A, Allegri F, Yadav H, Solimene U, Kumaraju AK, Minelli E, Tomella C, Polimeni A, Marotta F. Inhibiting insulin resistance mechanisms by DTS phytocompound: an experimental study on metabolic syndrome-prone adipocytes. Acta Biomed. 2012 Aug; 83(2):95-102. PMID: 23393916.
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    30. Nagpal R, Kumar A, Kumar M, Behare PV, Jain S, Yadav H. Probiotics, their health benefits and applications for developing healthier foods: a review. FEMS Microbiol Lett. 2012 Sep; 334(1):1-15. PMID: 22568660.
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    31. Kumar M, Nagpal R, Kumar R, Hemalatha R, Verma V, Kumar A, Chakraborty C, Singh B, Marotta F, Jain S, Yadav H. Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. Exp Diabetes Res. 2012; 2012:902917. PMID: 22611376; PMCID: PMC3352670.
    32. Marotta F, Yadav H, Kumari A, Catanzaro R, Jain S, Polimeni A, Lorenzetti A, Soresi V. Cardioprotective effect of a biofermented nutraceutical on endothelial function in healthy middle-aged subjects. Rejuvenation Res. 2012 Apr; 15(2):178-81. PMID: 22533427.
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    33. Marotta F, Kumari A, Yadav H, Polimeni A, Soresi V, Lorenzetti A, Naito Y, Jain S. Biomarine extracts significantly protect from ultraviolet A-induced skin photoaging: an ex vivo study. Rejuvenation Res. 2012 Apr; 15(2):157-60. PMID: 22533422.
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    34. Marotta F, Catanzaro R, Yadav H, Jain S, Tomella C, Polimeni A, Mantello P. Functional foods in genomic medicine: a review of fermented papaya preparation research progress. Acta Biomed. 2012 Apr; 83(1):21-9. PMID: 22978054.
      View in: PubMed
    35. Yadav H, Rane SG. TGF-ß/Smad3 Signaling Regulates Brown Adipocyte Induction in White Adipose Tissue. Front Endocrinol (Lausanne). 2012; 3:35. PMID: 22654861; PMCID: PMC3356034.
    36. Devalaraja S, Jain S, Yadav H. Exotic Fruits as Therapeutic Complements for Diabetes, Obesity and Metabolic Syndrome. Food Res Int. 2011 Aug 01; 44(7):1856-1865. PMID: 21857774.
      View in: PubMed
    37. Yadav H, Quijano C, Kamaraju AK, Gavrilova O, Malek R, Chen W, Zerfas P, Zhigang D, Wright EC, Stuelten C, Sun P, Lonning S, Skarulis M, Sumner AE, Finkel T, Rane SG. Protection from obesity and diabetes by blockade of TGF-ß/Smad3 signaling. Cell Metab. 2011 Jul 06; 14(1):67-79. PMID: 21723505.
      View in: PubMed
    38. Kim YC, Kim SY, Mellado-Gil JM, Yadav H, Neidermyer W, Kamaraju AK, Rane SG. RB regulates pancreas development by stabilizing Pdx1. EMBO J. 2011 Apr 20; 30(8):1563-76. PMID: 21399612; PMCID: PMC3102287.
    39. Nagpal R, Behare P, Rana R, Kumar A, Kumar M, Arora S, Morotta F, Jain S, Yadav H. Bioactive peptides derived from milk proteins and their health beneficial potentials: an update. Food Funct. 2011 Jan; 2(1):18-27. PMID: 21773582.
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    40. Yadav M, Jain S, Tomar R, Prasad GB, Yadav H. Medicinal and biological potential of pumpkin: an updated review. Nutr Res Rev. 2010 Dec; 23(2):184-90. PMID: 21110905.
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    41. Jain S, Yadav H, Sinha PR, Kapila S, Naito Y, Marotta F. Anti-allergic effects of probiotic Dahi through modulation of the gut immune system. Turk J Gastroenterol. 2010 Sep; 21(3):244-50. PMID: 20931427.
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    42. Shrivastava A, Khan AA, Jain SK, Singhal PK, Jain S, Marotta F, Yadav H. Biotechnological advancement in isolation of anti-neoplastic compounds from natural origin: a novel source of L-asparaginase. Acta Biomed. 2010 Sep; 81(2):104-8. PMID: 21305874.
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    43. Kumar M, Kumar A, Nagpal R, Mohania D, Behare P, Verma V, Kumar P, Poddar D, Aggarwal PK, Henry CJ, Jain S, Yadav H. Cancer-preventing attributes of probiotics: an update. Int J Food Sci Nutr. 2010 Aug; 61(5):473-96. PMID: 20187714.
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    44. Marotta F, Harada M, Minelli E, Yadav H, Polimeni A, Lorenzetti A, Locorotondo N. Progression of atherosclerotic lesions in the arteries and related gene expression: protective effect of phytonutrients. Rejuvenation Res. 2010 Apr-Jun; 13(2-3):242-5. PMID: 20370493.
      View in: PubMed
    45. Yadav M, Lavania A, Tomar R, Prasad GB, Jain S, Yadav H. Complementary and comparative study on hypoglycemic and antihyperglycemic activity of various extracts of Eugenia jambolana seed, Momordica charantia fruits, Gymnema sylvestre, and Trigonella foenum graecum seeds in rats. Appl Biochem Biotechnol. 2010 Apr; 160(8):2388-400. PMID: 19904502.
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    46. Jain S, Yadav H, Sinha PR. Antioxidant and cholesterol assimilation activities of selected lactobacilli and lactococci cultures. J Dairy Res. 2009 Nov; 76(4):385-91. PMID: 19638266.
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    47. Jain S, Yadav H, Sinha PR. Probiotic dahi containing Lactobacillus casei protects against Salmonella enteritidis infection and modulates immune response in mice. J Med Food. 2009 Jun; 12(3):576-83. PMID: 19627206.
      View in: PubMed
    48. Yadav M, Jain S, Bhardwaj A, Nagpal R, Puniya M, Tomar R, Singh V, Parkash O, Prasad GB, Marotta F, Yadav H. Biological and medicinal properties of grapes and their bioactive constituents: an update. J Med Food. 2009 Jun; 12(3):473-84. PMID: 19627194.
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    49. Lin HM, Lee JH, Yadav H, Kamaraju AK, Liu E, Zhigang D, Vieira A, Kim SJ, Collins H, Matschinsky F, Harlan DM, Roberts AB, Rane SG. Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function. J Biol Chem. 2009 May 01; 284(18):12246-57. PMID: 19265200; PMCID: PMC2673293.
    50. Jain S, Yadav H, Sinha PR, Marotta F. Modulation of cytokine gene expression in spleen and Peyer's patches by feeding dahi containing probiotic Lactobacillus casei in mice. J Dig Dis. 2009 Feb; 10(1):49-54. PMID: 19236547.
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    51. Marotta F, Yadav H, Gumaste U, Helmy A, Jain S, Minelli E. Protective effect of a phytocompound on oxidative stress and DNA fragmentation against paracetamol-induced liver damage. Ann Hepatol. 2009 Jan-Mar; 8(1):50-6. PMID: 19221534.
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    52. Singh V, Singh K, Amdekar S, Singh DD, Tripathi P, Sharma GL, Yadav H. Innate and specific gut-associated immunity and microbial interference. FEMS Immunol Med Microbiol. 2009 Jan; 55(1):6-12. PMID: 19077031.
      View in: PubMed
    53. Jain S, Yadav H, Sinha PR. Stimulation of innate immunity by oral administration of dahi containing probiotic Lactobacillus casei in mice. J Med Food. 2008 Dec; 11(4):652-6. PMID: 19053856.
      View in: PubMed
    54. Mohania D, Nagpal R, Kumar M, Bhardwaj A, Yadav M, Jain S, Marotta F, Singh V, Parkash O, Yadav H. Molecular approaches for identification and characterization of lactic acid bacteria. J Dig Dis. 2008 Nov; 9(4):190-8. PMID: 18959589.
      View in: PubMed
    55. Yadav H, Jain S, Sinha PR. Oral administration of dahi containing probiotic Lactobacillus acidophilus and Lactobacillus casei delayed the progression of streptozotocin-induced diabetes in rats. J Dairy Res. 2008 May; 75(2):189-95. PMID: 18474136.
      View in: PubMed
    56. Yadav H, Jain S, Sinha PR. The effect of probiotic dahi containing Lactobacillus acidophilus and Lactobacillus casei on gastropathic consequences in diabetic rats. J Med Food. 2008 Mar; 11(1):62-8. PMID: 18361739.
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    57. Yadav H, Jain S, Prasad GB, Yadav M. Preventive effect of diabegon, a polyherbal preparation, during progression of diabetes induced by high-fructose feeding in rats. J Pharmacol Sci. 2007 Sep; 105(1):12-21. PMID: 17878707.
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    58. Yadav H, Jain S, Sinha PR. Formation of oligosaccharides in skim milk fermented with mixed dahi cultures, Lactococcus lactis ssp diacetylactis and probiotic strains of lactobacilli. J Dairy Res. 2007 May; 74(2):154-9. PMID: 17291388.
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    59. Yadav H, Jain S, Sinha PR. Antidiabetic effect of probiotic dahi containing Lactobacillus acidophilus and Lactobacillus casei in high fructose fed rats. Nutrition. 2007 Jan; 23(1):62-8. PMID: 17084593.
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    60. Yadav H, Jain S, Sinha PR. Effect of Dahi containing Lactococcus lactis on the progression of diabetes induced by a high-fructose diet in rats. Biosci Biotechnol Biochem. 2006 May; 70(5):1255-8. PMID: 16717431.
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    61. Yadav H, Jain S, Sinha PR. Effect of skim milk and dahi (yogurt) on blood glucose, insulin, and lipid profile in rats fed with high fructose diet. J Med Food. 2006; 9(3):328-35. PMID: 17004894.
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    62. Yadav H, Jain S, Kapila S, Prasad G. Internet resources for diabetes. Indian J Med Sci. 2005 Jan; 59(1):32-42. PMID: 15681892.
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