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Clinical and Translational Science Institute

Keywords
Last Name

Chadwick David Miller, M.D.

TitleChair
InstitutionWake Forest School of Medicine
DepartmentEmergency Medicine
Address
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentCTSI

    TitleChair
    InstitutionWake Forest School of Medicine
    DepartmentEmergency Medicine


    Collapse Research 
    Collapse research activities and funding
    R21HL097131     (MILLER, CHADWICK DAVID)Jan 15, 2010 - Dec 31, 2012
    NIH/NHLBI
    Randomized Investigation of Chest Pain Diagnostic Strategies
    Role: Principal Investigator

    R01HL118263     (MILLER, CHADWICK DAVID)Jun 5, 2013 - Jan 31, 2019
    NIH/NHLBI
    CMR-IMPACT
    Role: Principal Investigator

    U01HL123027     (MILLER, CHADWICK DAVID)Jun 17, 2014 - Apr 30, 2021
    NIH/NHLBI
    Wake Forest Clinical Center for the NHLBI PETAL Network
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Stopyra JP, Riley RF, Hiestand BC, Russell GB, Hoekstra JW, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Elliott SB, Herrington DM, Burke GL, Miller CD, Mahler SA. The HEART Pathway Randomized Controlled Trial One-year Outcomes. Acad Emerg Med. 2019 Jan; 26(1):41-50. PMID: 29920834.
      View in: PubMed
    2. Mahler SA, Register TC, Riley RF, D'Agostino RB, Stopyra JP, Miller CD. Monocyte Chemoattractant Protein-1 as a Predictor of Coronary Atherosclerosis in Patients Receiving Coronary Angiography. Crit Pathw Cardiol. 2018 06; 17(2):105-110. PMID: 29768320.
      View in: PubMed
    3. Stopyra JP, Harper WS, Higgins TJ, Prokesova JV, Winslow JE, Nelson RD, Alson RL, Davis CA, Russell GB, Miller CD, Mahler SA. Prehospital Modified HEART Score Predictive of 30-Day Adverse Cardiac Events. Prehosp Disaster Med. 2018 Feb; 33(1):58-62. PMID: 29316995.
      View in: PubMed
    4. Stopyra JP, Miller CD, Hiestand BC, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Riley RF, Russell GB, Hoekstra JW, Mahler SA. Validation of the No Objective Testing Rule and Comparison to the HEART Pathway. Acad Emerg Med. 2017 09; 24(9):1165-1168. PMID: 28493646.
      View in: PubMed
    5. Stopyra JP, Miller CD, Mahler SA. In Reply. Acad Emerg Med. 2017 09; 24(9):1171-1172. PMID: 28608431.
      View in: PubMed
    6. Bittner DO, Mayrhofer T, Bamberg F, Hallett TR, Janjua S, Addison D, Nagurney JT, Udelson JE, Lu MT, Truong QA, Woodard PK, Hollander JE, Miller C, Chang AM, Singh H, Litt H, Hoffmann U, Ferencik M. Impact of Coronary Calcification on Clinical Management in Patients With Acute Chest Pain. Circ Cardiovasc Imaging. 2017 May; 10(5). PMID: 28487318.
      View in: PubMed
    7. Mahler SA, Stopyra JP, Apple FS, Riley RF, Russell GB, Hiestand BC, Hoekstra JW, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Herrington DM, Burke GL, Miller CD. Use of the HEART Pathway with high sensitivity cardiac troponins: A secondary analysis. Clin Biochem. 2017 May; 50(7-8):401-407. PMID: 28087371.
      View in: PubMed
    8. Stopyra JP, Miller CD, Hiestand BC, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Riley RF, Russell GB, Burke GL, Herrington D, Hoekstra JW, Mahler SA. Chest Pain Risk Stratification: A Comparison of the 2-Hour Accelerated Diagnostic Protocol (ADAPT) and the HEART Pathway. Crit Pathw Cardiol. 2016 06; 15(2):46-9. PMID: 27183253.
      View in: PubMed
    9. Mahler SA, Burke GL, Duncan PW, Case LD, Herrington DM, Riley RF, Wells BJ, Hiestand BC, Miller CD. HEART Pathway Accelerated Diagnostic Protocol Implementation: Prospective Pre-Post Interrupted Time Series Design and Methods. JMIR Res Protoc. 2016 Jan 22; 5(1):e10. PMID: 26800789.
      View in: PubMed
    10. Mahler SA, Riley RF, Russell GB, Hiestand BC, Hoekstra JW, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Bringolf J, Elliott SB, Herrington DM, Burke GL, Miller CD. Adherence to an Accelerated Diagnostic Protocol for Chest Pain: Secondary Analysis of the HEART Pathway Randomized Trial. Acad Emerg Med. 2016 Jan; 23(1):70-7. PMID: 26720295.
      View in: PubMed
    11. Stopyra JP, Miller CD, Hiestand BC, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Riley RF, Russell GB, Hoekstra JW, Mahler SA. Performance of the EDACS-accelerated Diagnostic Pathway in a Cohort of US Patients with Acute Chest Pain. Crit Pathw Cardiol. 2015 Dec; 14(4):134-8. PMID: 26569652.
      View in: PubMed
    12. Gardner AR, Diz DI, Tooze JA, Miller CD, Petty J. Injury patterns associated with hypotension in pediatric trauma patients: A national trauma database review. J Trauma Acute Care Surg. 2015 Jun; 78(6):1143-8. PMID: 26151515.
      View in: PubMed
    13. Mahler SA, Miller CD, Litt HI, Gatsonis CA, Snyder BS, Hollander JE. Performance of the 2-hour accelerated diagnostic protocol within the American College of Radiology Imaging Network PA 4005 cohort. Acad Emerg Med. 2015 Apr; 22(4):452-60. PMID: 25810343.
      View in: PubMed
    14. Mahler SA, Riley RF, Hiestand BC, Russell GB, Hoekstra JW, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Elliott SB, Herrington DM, Burke GL, Miller CD. The HEART Pathway randomized trial: identifying emergency department patients with acute chest pain for early discharge. Circ Cardiovasc Qual Outcomes. 2015 Mar; 8(2):195-203. PMID: 25737484.
      View in: PubMed
    15. Gardner A, Poehling KA, Miller CD, Tooze JA, Petty J. Isolated head injury is a cause of shock in pediatric trauma patients. Pediatr Emerg Care. 2013 Aug; 29(8):879-83. PMID: 23903673.
      View in: PubMed
    16. Mahler SA, Burke GL, Goff DC, Hiestand BC, Nicks BA, Hoekstra JW, Case LD, Miller CD. Avoidable utilization of the chest pain observation unit: evaluation of very-low-risk patients. Crit Pathw Cardiol. 2013 Jun; 12(2):59-64. PMID: 23680810.
      View in: PubMed
    17. Miller CD, Case LD, Little WC, Mahler SA, Burke GL, Harper EN, Lefebvre C, Hiestand B, Hoekstra JW, Hamilton CA, Hundley WG. Stress CMR reduces revascularization, hospital readmission, and recurrent cardiac testing in intermediate-risk patients with acute chest pain. JACC Cardiovasc Imaging. 2013 Jul; 6(7):785-94. PMID: 23664718.
      View in: PubMed
    18. Mahler SA, Hiestand BC, Nwanaji-Enwerem J, Goff DC, Burke GL, Douglas Case L, Nicks B, Miller CD. Reduction in observation unit length of stay with coronary computed tomography angiography depends on time of emergency department presentation. Acad Emerg Med. 2013 Mar; 20(3):231-9. PMID: 23517254.
      View in: PubMed
    19. Mahler SA, Miller CD, Hollander JE, Nagurney JT, Birkhahn R, Singer AJ, Shapiro NI, Glynn T, Nowak R, Safdar B, Peberdy M, Counselman FL, Chandra A, Kosowsky J, Neuenschwander J, Schrock JW, Plantholt S, Diercks DB, Peacock WF. Identifying patients for early discharge: performance of decision rules among patients with acute chest pain. Int J Cardiol. 2013 Sep 30; 168(2):795-802. PMID: 23117012.
      View in: PubMed
    20. Miller CD, Thomas MJ, Hiestand B, Samuel MP, Wilson MD, Sawyer J, Rudel LL. Cholesteryl esters associated with acyl-CoA:cholesterol acyltransferase predict coronary artery disease in patients with symptoms of acute coronary syndrome. Acad Emerg Med. 2012 Jun; 19(6):673-82. PMID: 22687182.
      View in: PubMed
    21. Hall ME, Miller CD, Hundley WG. Adenosine stress cardiovascular magnetic resonance-observation unit management of patients at intermediate risk for acute coronary syndrome: a possible strategy for reducing healthcare-related costs. Curr Treat Options Cardiovasc Med. 2012 Feb; 14(1):117-25. PMID: 22127744.
      View in: PubMed
    22. Miller CD, Hoekstra JW, Lefebvre C, Blumstein H, Hamilton CA, Harper EN, Mahler S, Diercks DB, Neiberg R, Hundley WG. Provider-directed imaging stress testing reduces health care expenditures in lower-risk chest pain patients presenting to the emergency department. Circ Cardiovasc Imaging. 2012 Jan; 5(1):111-8. PMID: 22128195.
      View in: PubMed
    23. Mahler SA, Hiestand BC, Goff DC, Hoekstra JW, Miller CD. Can the HEART score safely reduce stress testing and cardiac imaging in patients at low risk for major adverse cardiac events? Crit Pathw Cardiol. 2011 Sep; 10(3):128-33. PMID: 21989033.
      View in: PubMed
    24. Miller CD, Hwang W, Case D, Hoekstra JW, Lefebvre C, Blumstein H, Hamilton CA, Harper EN, Hundley WG. Stress CMR imaging observation unit in the emergency department reduces 1-year medical care costs in patients with acute chest pain: a randomized study for comparison with inpatient care. JACC Cardiovasc Imaging. 2011 Aug; 4(8):862-70. PMID: 21835378.
      View in: PubMed
    25. Miller CD, Litt HI, Askew K, Entrikin D, Carr JJ, Chang AM, Kilkenny J, Weisenthal B, Hollander JE. Implications of 25% to 50% coronary stenosis with cardiac computed tomographic angiography in ED patients. Am J Emerg Med. 2012 May; 30(4):597-605. PMID: 21524881.
      View in: PubMed
    26. Pollack CV, Schreiber D, Goldhaber SZ, Slattery D, Fanikos J, O'Neil BJ, Thompson JR, Hiestand B, Briese BA, Pendleton RC, Miller CD, Kline JA. Clinical characteristics, management, and outcomes of patients diagnosed with acute pulmonary embolism in the emergency department: initial report of EMPEROR (Multicenter Emergency Medicine Pulmonary Embolism in the Real World Registry). J Am Coll Cardiol. 2011 Feb 08; 57(6):700-6. PMID: 21292129.
      View in: PubMed
    27. Collins SP, Pang PS, Lindsell CJ, Kyriacou DN, Storrow AB, Hollander JE, Kirk JD, Miller CD, Nowak R, Peacock WF, Tavares M, Mebazaa A, Gheorghiade M. International variations in the clinical, diagnostic, and treatment characteristics of emergency department patients with acute heart failure syndromes. Eur J Heart Fail. 2010 Nov; 12(11):1253-60. PMID: 20797987.
      View in: PubMed
    28. Miller CD, Hwang W, Hoekstra JW, Case D, Lefebvre C, Blumstein H, Hiestand B, Diercks DB, Hamilton CA, Harper EN, Hundley WG. Stress cardiac magnetic resonance imaging with observation unit care reduces cost for patients with emergent chest pain: a randomized trial. Ann Emerg Med. 2010 Sep; 56(3):209-219.e2. PMID: 20554078.
      View in: PubMed
    29. Kline JA, Hogg MM, Courtney DM, Miller CD, Jones AE, Smithline HA, Klekowski N, Lanier R. D-dimer and exhaled CO2/O2 to detect segmental pulmonary embolism in moderate-risk patients. Am J Respir Crit Care Med. 2010 Sep 01; 182(5):669-75. PMID: 20448094.
      View in: PubMed
    30. Kline JA, Courtney DM, Than MP, Hogg K, Miller CD, Johnson CL, Smithline HA. Accuracy of very low pretest probability estimates for pulmonary embolism using the method of attribute matching compared with the Wells score. Acad Emerg Med. 2010 Feb; 17(2):133-41. PMID: 20370742.
      View in: PubMed
    31. Heitz CR, Gaillard JP, Blumstein H, Case D, Messick C, Miller CD. Performance of the maximum modified early warning score to predict the need for higher care utilization among admitted emergency department patients. J Hosp Med. 2010 Jan; 5(1):E46-52. PMID: 20063289.
      View in: PubMed
    32. Courtney DM, Miller C, Smithline H, Klekowski N, Hogg M, Kline JA. Prospective multicenter assessment of interobserver agreement for radiologist interpretation of multidetector computerized tomographic angiography for pulmonary embolism. J Thromb Haemost. 2010 Mar; 8(3):533-9. PMID: 20015156.
      View in: PubMed
    33. Miller CD, Blomkalns AL, Gersh BJ, Pollack CV, Brogan GX, Diercks DB, Peacock WF, Stone GW, Hollander JE, Manoukian SV, Hoekstra JW. Safety and efficacy of bivalirudin in high-risk patients admitted through the emergency department. Acad Emerg Med. 2009 Aug; 16(8):717-25. PMID: 19673711.
      View in: PubMed
    34. Singer AJ, Birkhahn RH, Guss D, Chandra A, Miller CD, Tiffany B, Levy P, Dunne R, Bastani A, Thode HC, Hollander JE. Rapid Emergency Department Heart Failure Outpatients Trial (REDHOT II): a randomized controlled trial of the effect of serial B-type natriuretic peptide testing on patient management. Circ Heart Fail. 2009 Jul; 2(4):287-93. PMID: 19808351.
      View in: PubMed
    35. Collins SP, Levy PD, Lindsell CJ, Pang PS, Storrow AB, Miller CD, Naftilan AJ, Thohan V, Abraham WT, Hiestand B, Filippatos G, Diercks DB, Hollander J, Nowak R, Peacock WF, Gheorghiade M. The rationale for an acute heart failure syndromes clinical trials network. J Card Fail. 2009 Aug; 15(6):467-74. PMID: 19643356.
      View in: PubMed
    36. Miller CD, Kumar R, Storrow AB. Alignment of emergency medicine research efforts with Clinical and Translational Science Awards. Acad Emerg Med. 2008 Jul; 15(7):672-7. PMID: 19086215.
      View in: PubMed
    37. Roe MT, Kikano G, Miller CD, Hoekstra JW. Continuum of care in the treatment of ST-segment elevation myocardial infarction (STEMI): importance of platelet and coagulation inhibition. Postgrad Med. 2008 Jul; 120(2):67-78. PMID: 18654071.
      View in: PubMed
    38. Pang PS, Tavares M, Collins SP, Cleland JG, Hollander J, Nieminen M, Miller C, Courtney DM, Kirk JD, Masip J, Parkhomenko A, Macarie C, Peacock WF, Spinar J, Nowak R, Raev D, Storrow AB, Spisak V, Hamdy A, Mebazaa A, Gheorghiade M. Design and rationale of the URGENT Dyspnea study: an international, multicenter, prospective study. Am J Ther. 2008 Jul-Aug; 15(4):299-303. PMID: 18645329.
      View in: PubMed
    39. White HD, Chew DP, Hoekstra JW, Miller CD, Pollack CV, Feit F, Lincoff AM, Bertrand M, Pocock S, Ware J, Ohman EM, Mehran R, Stone GW. Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial. J Am Coll Cardiol. 2008 May 06; 51(18):1734-41. PMID: 18452778.
      View in: PubMed
    40. Boden WE, Hoekstra J, Miller CD. ST-elevation myocardial infarction: the role of adjunctive antiplatelet therapy. Am J Emerg Med. 2008 Feb; 26(2):212-20. PMID: 18272105.
      View in: PubMed
    41. Miller CD, Roe MT, Mulgund J, Hoekstra JW, Santos R, Pollack CV, Ohman EM, Gibler WB, Peterson ED. Impact of acute beta-blocker therapy for patients with non-ST-segment elevation myocardial infarction. Am J Med. 2007 Aug; 120(8):685-92. PMID: 17679127.
      View in: PubMed
    42. Han JH, Lindsell CJ, Hornung RW, Lewis T, Storrow AB, Hoekstra JW, Hollander JE, Miller CD, Peacock WF, Pollack CV, Gibler WB. The elder patient with suspected acute coronary syndromes in the emergency department. Acad Emerg Med. 2007 Aug; 14(8):732-9. PMID: 17567963.
      View in: PubMed
    43. Miller CD, Banerjee A, Mahaffey KW, Kontos MC, Fermann G, Pollack CV, Antman E, Aylward P, Goodman SG, Santos R, Ferguson JJ, Califf RM, Hoekstra JW. Treatment and outcomes of patients with evolving myocardial infarction: experiences from the SYNERGY trial. Eur Heart J. 2007 May; 28(9):1079-84. PMID: 17405770.
      View in: PubMed
    44. Miller CD, Lindsell CJ, Anantharaman V, Lim SH, Greenway J, Pollack CV, Tiffany BR, Hollander JE, Gibler WB, Hoekstra JW. Performance of a population-based cardiac risk stratification tool in Asian patients with chest pain. Acad Emerg Med. 2005 May; 12(5):423-30. PMID: 15863398.
      View in: PubMed
    45. Hoekstra JW, Roe MT, Peterson ED, Menon V, Mulgund J, Pollack CV, Miller C, Palabrica T, Harrington RA, Ohman EM, Gibler WB. Early glycoprotein IIb/IIIa inhibitor use for non-ST-segment elevation acute coronary syndrome: patient selection and associated treatment patterns. Acad Emerg Med. 2005 May; 12(5):431-8. PMID: 15863399.
      View in: PubMed
    46. Miller CD, Lindsell CJ, Khandelwal S, Chandra A, Pollack CV, Tiffany BR, Hollander JE, Gibler WB, Hoekstra JW. Is the initial diagnostic impression of "noncardiac chest pain" adequate to exclude cardiac disease? Ann Emerg Med. 2004 Dec; 44(6):565-74. PMID: 15573030.
      View in: PubMed
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