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Clinical and Translational Science Institute

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Transient Receptor Potential Channels

"Transient Receptor Potential Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN repeats are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.

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This graph shows the total number of publications written about "Transient Receptor Potential Channels" by people in this website by year, and whether "Transient Receptor Potential Channels" was a major or minor topic of these publications.
Bar chart showing 3 publications over 2 distinct years, with a maximum of 2 publications in 2010
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